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Epigenetic regulation linked with pathogenesis of Alzheimer's disease

New evidence presented at the 26th ECNP Congress linking epigenetic regulation with Alzheimer's disease may one day lead to new early diagnostic tests and even novel treatment options for the most common form of dementia.

7 Oct 2013

Scientists at Oklahoma Medical Research Foundation identify six new Sj-gren-related genes

With the completion of the first genome-wide association study for Sj-gren's syndrome, an international coalition of researchers led by scientists at the Oklahoma Medical Research Foundation has identified six new disease-related genes.

7 Oct 2013

ERK pathway discovery may provide therapeutic options for treating drug addictions

The extracellular-signal regulated kinase (ERK) pathway plays a role in multiple drug addictions and appears to modulate neuronal plasticity through epigenetic mechanisms, say French scientists.

7 Oct 2013

AbbVie announces HUMIRA phase II study results for treating hidradenitis suppurativa

AbbVie (NYSE: ABBV) today announced results from a post-hoc analysis of an investigational Phase II study, which evaluated HUMIRA® (adalimumab) in the treatment of patients with moderate-to-severe hidradenitis suppurativa (HS) after 16 weeks of therapy.

7 Oct 2013

Boreal Genomics announces completion of $18 million Series C financing round

Boreal Genomics, a privately held provider of technology for non-invasive genomic profiling of tumors from blood plasma of cancer patients, announced today the completion of an $18 million Series C financing round.

5 Oct 2013

Researchers reveals mechanism of sodium-potassium pump in cell

It's not visible to the naked eye and you can't feel it, but up to 40 per cent of your body's energy goes into supplying the microscopic sodium-potassium pump with the energy it needs. The pump is constantly doing its job in every cell of all animals and humans. It works much like a small battery which, among other things, maintains the sodium balance which is crucial to keep muscles and nerves working.

5 Oct 2013

New biomarker for pancreatic cancer effectively targets potential therapy for small survival rate

University of Cincinnati (UC) researchers have discovered a biomarker, known as phosphatidylserine (PS), for pancreatic cancer that could be effectively targeted, creating a potential therapy for a condition that has a small survival rate.

5 Oct 2013

Researchers discover way to use stem cells as drug delivery vehicles

A group of Brigham and Women's Hospital, and Harvard Stem Cell Institute researchers and collaborators at MIT and MGH have found a way to use stem cells as drug delivery vehicles.

5 Oct 2013

Amgen presents data from several romosozumab and Prolia at ASBMR 2013 Annual Meeting

Amgen today announced that it will present data from several romosozumab and Prolia® (denosumab) studies at the American Society for Bone and Mineral Research (ASBMR) 2013 Annual Meeting in Baltimore from Oct. 4-7, 2013.

5 Oct 2013

Modern strains of MRSA have become broadly resistant to antibiotics: Study

University of Notre Dame researchers Shahriar Mobashery and Mayland Chang and their collaborators in Spain have published research results this week that show how methicillin-resistant Staphylococcus aureus (MRSA) regulates the critical crosslinking of its cell wall in the face of beta-lactam antibiotics.

5 Oct 2013

Dying heart cells are kept alive with spikes of oxygen

In a study published in published in EMBO Molecular Medicine, a Dartmouth researcher found that dying heart cells are kept alive with spikes of oxygen.

5 Oct 2013

Researchers develop new method to identify genes involved in kidney diseases

Understanding how genes act in specific tissues is critical to our ability to combat many human diseases, from heart disease to kidney failure to cancer. Yet isolating individual cell types for study is impossible for most human tissues.

5 Oct 2013

Study identifies new potential genetic culprits in origins of congenital heart defects

Mitochondria are the power plants of cells, manufacturing chemical fuel so a cell can perform its many tasks. These cellular power plants also are well known for their role in ridding the body of old or damaged cells.

5 Oct 2013

New therapeutic targets and drugs may benefit people with leukemia

An Indiana University cancer researcher and his colleagues have discovered new therapeutic targets and drugs that may someday benefit people with certain types of leukemia or blood cancer.

5 Oct 2013

BioTek’s cell imaging multi-mode reader wins New Product Innovation Award

BioTek’s Cytation™3 Cell Imaging Multi-Mode Reader was recently honored with the first annual New Product Innovation Award, given by MipTec organizers at the 2013 MipTec Conference & Exhibition in Basel, Switzerland. Cytation3 was one of three winning products announced at the exhibition on September 25, 2013.

4 Oct 2013

Active ingredient of ipecac syrup inhibits growth of cancer cells

An old home remedy called ipecac syrup, once stocked in medicine cabinets in case of accidental poisoning, is showing promise as a new chemotherapy drug for bladder cancer.

4 Oct 2013

Scientists uncover new approach to develop induced pluripotent stem cells for in vivo disease modeling

In a paper in Cell Stem Cell, a team led by researchers in the Boston Children's Hospital's Stem Cell Transplantation Program reports a new approach for turning induced pluripotent stem cells (iPSCs) into hematopoietic stem and progenitor cells for in vivo disease modeling.

4 Oct 2013

Scientists identify chemical agents that block flu virus's ability to replicate itself in cell culture

A new way to attack flu viruses is taking shape in laboratories at Rutgers University, where scientists have identified chemical agents that block the virus's ability to replicate itself in cell culture.

4 Oct 2013

Researchers suggest new view of how stem cells may help repair brain following trauma

University of South Florida researchers have suggested a new view of how stem cells may help repair the brain following trauma. In a series of preclinical experiments, they report that transplanted cells appear to build a "biobridge" that links an uninjured brain site where new neural stem cells are born with the damaged region of the brain.

4 Oct 2013

New picture of interaction between nervous & immune systems could lead to novel therapies

A new picture of how the nervous system interacts with the immune system to cause the itch and inflammation associated with eczema, a chronic skin disease, could lead to new therapies for the condition, according to University of California, Berkeley, scientists.

4 Oct 2013

Cell News and Research

Epigenetic regulation linked with pathogenesis of Alzheimer's disease

Scientists at Oklahoma Medical Research Foundation identify six new Sj-gren-related genes

ERK pathway discovery may provide therapeutic options for treating drug addictions

AbbVie announces HUMIRA phase II study results for treating hidradenitis suppurativa

Boreal Genomics announces completion of $18 million Series C financing round

Researchers reveals mechanism of sodium-potassium pump in cell

New biomarker for pancreatic cancer effectively targets potential therapy for small survival rate

Researchers discover way to use stem cells as drug delivery vehicles

Amgen presents data from several romosozumab and Prolia at ASBMR 2013 Annual Meeting

Modern strains of MRSA have become broadly resistant to antibiotics: Study

Dying heart cells are kept alive with spikes of oxygen

Researchers develop new method to identify genes involved in kidney diseases

Study identifies new potential genetic culprits in origins of congenital heart defects

New therapeutic targets and drugs may benefit people with leukemia

BioTek’s cell imaging multi-mode reader wins New Product Innovation Award

Active ingredient of ipecac syrup inhibits growth of cancer cells

Scientists uncover new approach to develop induced pluripotent stem cells for in vivo disease modeling

Scientists identify chemical agents that block flu virus's ability to replicate itself in cell culture

Researchers suggest new view of how stem cells may help repair brain following trauma

New picture of interaction between nervous & immune systems could lead to novel therapies

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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