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HIF-1 activity directly responsible for spread of breast cancer to lymph vessels

The invasion of cancer cells into the lymph vessels that connect the breast to surrounding lymph nodes is the first step leading to the metastasis, or spread, of cancer throughout the body. Metastasis is the primary cause of breast cancer deaths. Surprisingly little is known about the control of this process and how it might be interrupted to prolong the lives of women with breast cancer.

11 Sep 2012

Combining two drugs may offer new and potent punch against cancer and other diseases

A new study by researchers at Weill Cornell Medical College shows combining two already-FDA approved drugs may offer a new and potent punch against diseases in which blood vessel growth is abnormal -- such as cancer, diabetic retinopathy, macular degeneration and rheumatoid arthritis.

11 Sep 2012

Aortic stiffness linked to high blood pressure

Higher aortic stiffness is linked with an increased risk for hypertension, a study in JAMA suggests.

10 Sep 2012

Florida Hospital Tampa adopts FDA approved Trevo Pro Clot Retriever

Florida Hospital Tampa and Dr. James E. Lefler are the first in the Tampa Bay area to adopt the new FDA approved device called the Trevo Pro Clot Retriever manufactured by Stryker. The Trevo Pro is the next generation in clot removal technology.

10 Sep 2012

CPF to kick off 'Pulmonary Fibrosis Awareness Month'

Each year around the world, as many as 48,000 people are diagnosed with pulmonary fibrosis and 40,000 people die – the same number of people who are lost to breast cancer annually. Pulmonary fibrosis is a devastating disease that robs people of their ability to breathe. To help raise awareness about this unknown deadly disease, the Coalition for Pulmonary Fibrosis (CPF) is kicking off "Pulmonary Fibrosis Awareness Month" this September.

10 Sep 2012

New molecular pathway that leads to preeclampsia identified

Preeclampsia is one of the most dangerous conditions for the expectant mother and the unborn child and is characterized by elevated blood pressure and protein in the urine in the last trimester of pregnancy.

10 Sep 2012

Women at increased risk of adverse outcomes after surgery for moyamoya disease

Women and girls are at increased risk of adverse outcomes after surgical treatment for moyamoya disease, an uncommon but serious disease of the brain blood vessels, reports a study in the September issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

10 Sep 2012

NIH awards Immunetics $3.7M SBIR contract for Babesia infection blood screening test

Immunetics, Inc., has received a $3.7 million, two year SBIR contract from the National Heart, Lung and Blood Institute, an agency of the National Institutes of Health (NIH), to support clinical trials of a new blood screening test for Babesia infection.

10 Sep 2012

Enzymatic sculpting process used to isolate and concentrate cells from whole blood

In living systems, complex nano- and microscale structures perform a host of physical and biological functions. While two-dimensional patterns can be recreated fairly well with techniques like microlithography, three-dimensional structures represent a big challenge.

10 Sep 2012

Surprising new roles for angiotensin converting enzyme

At the 1st ECRC "Franz-Volhard" Symposium on September 7, 2012 at the Max Delbr-ck Center for Molecular Medicine (MDC) in Berlin-Buch, Professor Ken Bernstein reported that in mice an excess of ACE led to a much stronger immune response than usual.

10 Sep 2012

Skin, immune system play an important role in regulating sodium balance and hypertension

High blood pressure is responsible for many cardiovascular diseases that are the leading cause of death in industrialized countries. High salt intake has long been considered a risk factor, but not every type of high blood pressure is associated with high salt intake. This has puzzled scientists for a long time. However, new findings by Professor Jens Titze (Vanderbilt University, Nashville, Tennessee, USA and the University of Erlangen) now point to previously unknown mechanisms.

10 Sep 2012

Novel surgical technique removes invasive facial tumor, recreates functional lower jaw and mouth

Using a novel surgical approach, it's possible to rebuild a functional lower jaw and mouth, and preserve a patient's ability to eat and speak after removing an invasive facial tumor, according to a new report from Henry Ford Hospital in Detroit.

10 Sep 2012

Insight into how tissue stiffness drives cancer

The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering studies have found that breast cancer cells grown on a 3-D gel have enhanced cell replication and decreased organization as rigidity increases.

10 Sep 2012

Baylor Health Care System raises awareness about atrial fibrillation

An estimated 2.5 million Americans suffer from irregular heartbeats-also known as atrial fibrillation. Baylor Health Care System is raising awareness about this often misunderstood, but potentially life changing cardiovascular condition whose incidence is on the rise and expected to more than double by 2050.

10 Sep 2012

Endocrine Society issues practice guideline for diagnosis and treatment of hypertriglyceridemia

The Endocrine Society today issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of hypertriglyceridemia. Triglycerides are a type of fat found in the blood and are associated with cardiovascular risk. The CPG, entitled "Evaluation and Treatment of Hypertriglyceridemia: An Endocrine Society Clinical Practice Guideline" appears in the September 2012 issue of the Journal of Clinical Endocrinology and Metabolism (JCEM), a publication of The Endocrine Society.

10 Sep 2012

Tight blood sugar control does not benefit pediatric patients undergoing heart surgery

Although some studies have portrayed tight blood sugar control as a potential means of lowering infection rates in critically ill adults, a new study-led by principal investigator Michael Agus, MD, director of the Medicine Critical Care Program at Boston Children's Hospital-found no indication that the approach benefits pediatric patients undergoing heart surgery.

10 Sep 2012

Soy-rich diet can mitigate effects of bisphenol A

New research led by researchers at North Carolina State University shows that exposure to the chemical bisphenol A (BPA) early in life results in high levels of anxiety by causing significant gene expression changes in a specific region of the brain called the amygdala. The researchers also found that a soy-rich diet can mitigate these effects.

10 Sep 2012

New strategy will have positive impact on people with brain disorders

New research offers a possible strategy for treating central nervous system diseases, such as brain and spinal cord injury, brain cancer, epilepsy, and neurological complications of HIV. The experimental treatment method allows small therapeutic agents to safely cross the blood-brain barrier in laboratory rats by turning off P-glycoprotein, one of the main gatekeepers preventing medicinal drugs from reaching their intended targets in the brain.

10 Sep 2012

Cedars-Sinai receives CIRM grant to continue study of stem cell therapy for heart disease

A team of Cedars-Sinai Heart Institute stem cell researchers today was awarded a $1.3 million grant from the California Institute of Regenerative Medicine to continue study of an experimental stem cell therapy that treats heart attack patients with heart-derived cells. Earlier this year, data from the first clinical trial of the stem cell treatment showed the therapy helped damaged hearts regrow healthy muscle.

10 Sep 2012

Increased risk of heart failure and cardiovascular death linked to thickening of heart's right ventricle

Researchers at the Perelman School of Medicine at the University of Pennsylvania report in a new study that thickening of the heart's right ventricle is associated with an increased risk of heart failure and cardiovascular death in patients without clinical cardiovascular disease at baseline. The study is published online ahead of print in the journal Circulation.

7 Sep 2012

Blood News and Research

HIF-1 activity directly responsible for spread of breast cancer to lymph vessels

Combining two drugs may offer new and potent punch against cancer and other diseases

Aortic stiffness linked to high blood pressure

Florida Hospital Tampa adopts FDA approved Trevo Pro Clot Retriever

CPF to kick off 'Pulmonary Fibrosis Awareness Month'

New molecular pathway that leads to preeclampsia identified

Women at increased risk of adverse outcomes after surgery for moyamoya disease

NIH awards Immunetics $3.7M SBIR contract for Babesia infection blood screening test

Enzymatic sculpting process used to isolate and concentrate cells from whole blood

Surprising new roles for angiotensin converting enzyme

Skin, immune system play an important role in regulating sodium balance and hypertension

Novel surgical technique removes invasive facial tumor, recreates functional lower jaw and mouth

Insight into how tissue stiffness drives cancer

Baylor Health Care System raises awareness about atrial fibrillation

Endocrine Society issues practice guideline for diagnosis and treatment of hypertriglyceridemia

Tight blood sugar control does not benefit pediatric patients undergoing heart surgery

Soy-rich diet can mitigate effects of bisphenol A

New strategy will have positive impact on people with brain disorders

Cedars-Sinai receives CIRM grant to continue study of stem cell therapy for heart disease

Increased risk of heart failure and cardiovascular death linked to thickening of heart's right ventricle

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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