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EPHA3 mutations may be important drivers of lung cancers

Vanderbilt-Ingram Cancer Center researchers have identified how one of the genes most commonly mutated in lung cancer may promote such tumors.

31 Jul 2012

Gluconeogenesis severely compromised in HCC by IL6-Stat3-mediated activation of miR-23a

As liver cancer develops, tumor cells lose the ability to produce and release glucose into the bloodstream, a key function of healthy liver cells for maintaining needed blood-sugar levels.

31 Jul 2012

Researchers identify new genetic target for diuretic therapy

Researchers at the University of Cincinnati (UC) have identified a new genetic target for diuretic therapy in patients with fluid overload-like those with congestive heart failure, liver cirrhosis or kidney failure.

31 Jul 2012

National Marfan Foundation’s annual conference to be held in Chicago

The National Marfan Foundation is gearing up for its 28th Annual conference, held at Northwestern Memorial Hospital in Chicago, August 2-5. Hosted by Northwestern Medicine- and the Ann and Robert H. Lurie Children's Hospital of Chicago, the four-day conference has something for everyone with Marfan syndrome (MFS) and related disorders, including access to many of the top MFS experts in the world.

31 Jul 2012

ATP1A3 gene mutations responsible for alternating hemiplegia of childhood

Alternating hemiplegia of childhood (AHC) is a rare disorder that usually begins in infancy, with intermittent episodes of paralysis and stiffness, first affecting one side of the body, then the other. Symptoms mysteriously appear and disappear, again and again, and affected children often experience dozens of episodes per week. As they get older, children fall progressively behind their peers in both intellectual abilities and motor skills, and more than half develop epilepsy.

31 Jul 2012

Roundup: N.J. public may decide if judges should pay more for health care; Ore. Medicaid experiment to launch; Uncertainty around Va. abortion clinic rules

The New Jersey State Assembly is set to consider a measure that would allow voters to decide whether New Jersey judges should pay more for their pensions and health benefits. The state Supreme Court ruled last week that judges don't have to contribute more toward pensions and health care despite a new law requiring them to do so. The court said the law diminishes judges' salaries, which are protected by state law.

31 Jul 2012

A touch may go a long way for preterm babies

Therapeutic touch may have a protective effect on the autoregulation of cerebral blood flow in preterm neonates in response to pain, report researchers.

30 Jul 2012

Walking speed could explain high BP and mortality link in elderly

Elderly individuals with high systolic blood pressure who walk quickly have a higher mortality rate than their counterparts who walk more slowly, show US study results.

30 Jul 2012

Bathroom scale performs electrocardiograms

The Instrumentation, Sensors and Interfaces (ISI) Group has developed an intuitive and cost-effective scale, which, as well as measuring weight, also records the electrical activity of the heart from foot and hand contact. The device demonstrates the usefulness of telemedicine, which is particularly appropriate for people who need frequent heart checkups.

30 Jul 2012

Encouraging results from Tonix TNX-102 SL clinical trial for fibromyalgia syndrome

Tonix Pharmaceuticals Holding Corp., a specialty pharmaceutical company developing therapies for challenging disorders of the central nervous system, including fibromyalgia syndrome and post-traumatic stress disorder, announces that the clinical portion of a human study of a solution version of TNX-102 2.4 mg sublingual tablets has completed.

30 Jul 2012

Promising implications for improving cellular immunotherapy for treatment of cancer

New research from the Trudeau Institute laboratory of Dr. Edward L. Pearce (Washington University) has promising implications for improving a treatment for cancer known as cellular immunotherapy. The findings were just published in the The Journal of Immunology.

30 Jul 2012

Positive results from Vermillion OVA500 multi-center study for ovarian cancer

Vermillion, Inc., a leading molecular diagnostics company, today announced positive results from a new prospective, multi-center clinical study of its ovarian cancer diagnostic OVA1.

30 Jul 2012

EASL calls on the UN to take action to fight against viral hepatitis infection

Marking World Hepatitis Day, the European Association for the Study of the Liver (EASL) calls on the different organizations which make up the United Nations systems to take action to fight against Viral Hepatitis (Hepatitis B and C), a potentially fatal infection of the liver which affects 500 million people.

30 Jul 2012

Lack of physical activity and life expectancy: an interview with Dr I-Min Lee

With the approach of the Olympic Games, a group of researchers throughout the world thought that it would be a good time to draw the attention of the world to the health dangers of being physically inactive.

30 Jul 2012

Researchers describe new human tissue dendritic cell with cross-presenting function

Researchers in Newcastle and Singapore have identified a new type of white blood cell which activates a killing immune response to an external source - providing a new potential target for vaccines for conditions such as cancer or Hepatitis B.

30 Jul 2012

New assay method finds evidence of clonal evolution in chronic lymphocytic leukemia

Using a new assay method to study tumor cells, researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center have found evidence of clonal evolution in chronic lymphocytic leukemia (CLL).

30 Jul 2012

New compound effective at blocking damage to the retina in diabetic retinopathy

Researchers at the University of Michigan Kellogg Eye Center have identified a compound that could interrupt the chain of events that cause damage to the retina in diabetic retinopathy. The finding is significant because it could lead to a novel therapy that targets two mechanisms at the root of the disease: inflammation and the weakening of the blood barrier that protects the retina.

30 Jul 2012

Pre-hospital electrocardiography offers more timely diagnosis of heart attack

A study conducted by researchers from the University of California, San Diego School of Medicine along with colleagues from Rural/Metro Ambulance San Diego and the San Diego Fire-Rescue Department, shows that emergency medical personnel can obtain an electrocardiogram (ECG) in the field for chest pain patients without an increase in scene time or transport time to the hospital.

30 Jul 2012

Cedars-Sinai to develop stem cell treatments for patients with ALS

Cedars-Sinai Regenerative Medicine Institute today was awarded a $17.8 million grant from the California Institute for Regenerative Medicine to develop stem cell treatments for patients with ALS, also known as Lou Gehrig's Disease, a progressive, fatal and currently incurable neurodegenerative disease.

30 Jul 2012

Roofers have higher PAH blood-levels after 6-hour shift

Roofers and road construction workers who use hot asphalt are exposed to high levels of polycyclic aromatic hydrocarbons (PAHs). A University of Colorado Cancer Center study published this week in the British Medical Journal Open shows that roofers have higher PAH blood-levels after a shift than before and that these high levels of PAHs are linked with increased rates of DNA damage, and potentially with higher cancer risk.

28 Jul 2012