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Porvair and Suzhou Tianlong Bio to develop epigenetic analysis technologies

Porvair Sciences are teaming up with Suzhou Tianlong Bio Technology Co Ltd (China), together with Swansea University and Xi'an Jiaotong University in a collaborative project entitled, "Automating & Stratification of Epigenetics in Healthcare" that is part of the Innovate UK / Jiangsu Industrial Challenge Programme.

From Chromatrap® - Porvair Sciences Ltd 15 Dec 2017

Genentech researchers uncover epigenetic regulator of pancreatic cancer cells

Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin.

11 Dec 2017

Research suggests genome's spatial organization as important switch for defining cell types

During differentiation of pluripotent stem cells to cardiomyocytes, the three-dimensional folding of the DNA reorganizes itself. This reorganization of the DNA architecture precedes and defines important epigenetic patterns.

22 Nov 2017

$10 million gift creates new center at Northwestern University to study effects of environment on genes

A new $10 million gift from University trustees and supporters Louis A. Simpson '58 and Kimberly K. Querrey will create a center at Northwestern University Feinberg School of Medicine to study the effects of environment on the activation and expression of genes.

21 Nov 2017

Study shows promise and potential risk in reversing hearing loss using inner ear stem cells

Want to restore hearing by injecting stem cells into the inner ear? Well, that can be a double-edged sword.

7 Nov 2017

Research provides path to possible treatment for Fragile X Syndrome and other types of autism

In Fragile X Syndrome--the leading genetic form of intellectual disability and autism--the effects of a single defective gene ripple through a series of chemical pathways, altering signals between brain cells.

3 Nov 2017

Researchers analyze molecular processes that influence aging

Understanding the factors that control aging has been one of humanity's endless pursuits, from the mystical fountain of youth to practical healthful regimens to prolong life expectancy.

2 Nov 2017

Study: New histone modifications link cellular metabolism to chromatin architecture

Scientists of Helmholtz Zentrum München and Ludwig-Maximilians-Universität Munich (LMU) have discovered that two new classes of histone modifications couple cellular metabolism to gene activity. The study was published in 'Nature Structural and Molecular Biology'.

26 Oct 2017

New study describes how gene-environment interaction leads to congenital heart defects

Infants of mothers with diabetes have a three- to five-fold increased risk of congenital heart defects. Such developmental defects are likely caused by a combination of genetic and environmental factors.

19 Oct 2017

Study finds link between sleep duration and measure of chromosomal health in sperm

A new study found a link between sleep duration and a measure of chromosomal health in sperm. The findings are published in the Journal of Sleep Research.

16 Oct 2017

Study sheds new light on underlying genetic causes of congenital heart disease

Approximately one in every 100 babies is born with congenital heart disease (CHD), and CHD remains the leading cause of mortality from birth defects.

9 Oct 2017

Study on cell stress response may hold promise for treating inflammation-related disorders

Stress – defined broadly – can have a profoundly deleterious effect on the human body. Even individual cells have their own way of dealing with environmental strains such as ultraviolet radiation from the sun or germs.

4 Oct 2017

Biochemists discover genes that determine animal complexity

Genes which determine animal complexity – or what makes humans so much more complex than a fruit fly or a sea urchin – have been identified for the first time.

30 Sep 2017

Chromatrap ChIP-Seq kits can deliver streamlined protocol from nanograms of starting material

Chromatrap has demonstrated that its unique solid state patented technology allows for ChIP-seq assays to be routinely performed from as little as 500 ng of chromatin.

From Chromatrap® - Porvair Sciences Ltd 28 Sep 2017

Scientists use novel microscopy to illuminate chromosomal 'dark matter'

Using a microscope invented at the Marine Biological Laboratory (MBL), a collaborative team of biologists, instrument developers, and computational scientists has for the first time measured the density of a relatively inscrutable, highly condensed form of chromosomal material that appears in the cells of human beings and other eukaryotes.

13 Sep 2017

Molecular life scientists to gather in Jerusalem for 2017 FEBS Congress

Over 1,600 molecular life scientists from over 34 countries, will gather in Jerusalem from September 10-14 for the 2017 Federation of European Biochemical Societies Congress.

11 Sep 2017

Scientists directly convert skin cells from healthy adults into motor neurons

Scientists working to develop new treatments for neurodegenerative diseases have been stymied by the inability to grow human motor neurons in the lab. Motor neurons drive muscle contractions, and their damage underlies devastating diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy, both of which ultimately lead to paralysis and early death.

7 Sep 2017

UAB researchers reveal key role for RSF1 protein in silencing genes

A fertilized human egg develops into multiple tissues, organs and about 200 distinct cell types. Each cell type has the same genes, but they are expressed differently during development and in mature cells.

31 Aug 2017

Scientists identify novel role for retrotransposons in shaping embryonic chromatin landscape

Retrotransposons are repetitive elements that form almost half of the mammalian genome. Even though they are so common, they have previously been considered to be fairly insignificant.

30 Aug 2017

JAX wins NIGMS funding to decipher role of RNA structure in gene regulation

With new funding from the National Institute of General Medical Sciences totaling $2,059,618 over five years, JAX Assistant Professor Zhengqing Ouyang, Ph.D., will build a research program to reveal the roles of RNA structure in post-transcriptional regulation at the genome scale.

21 Aug 2017