Macrophage News and Research

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A macrophage is a type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.

Novel imaging method reveals in vivo localization of antibiotics in infected lung tissues

Researchers at the Francis Crick Institute and the University of Western Australia have developed a new imaging method to see where antibiotics have reached bacteria within tissues.

5 Jan 2021

Gut cells alert the body to danger during parasite invasion

To effectively combat an infection, the body first has to sense it's been invaded, then the affected tissue must send out signals to corral resources to fight the intruder.

28 Dec 2020

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Researchers at the Kobe University Graduate School of Medicine have revealed that alterations in fetal microglia resulting from maternal inflammation could contribute towards the onset of developmental and psychiatric disorders.

23 Dec 2020

Study provides new insights into the molecular underpinnings of Duchenne muscular dystrophy

A UT Southwestern research team has catalogued gene activity in the skeletal muscle of mice, comparing healthy animals to those carrying a genetic mutation that causes Duchene muscular dystrophy (DMD) in humans.

21 Dec 2020

COVID-19: Meta-analysis unveils adversely affected biological processes in infected lung cells

The researchers Wasco Wruck and Prof. James Adjaye from the Institute of Stem Cell Research and Regenerative Medicine, Medical Faculty of Heinrich-Heine-University Duesseldorf, Germany, employed a bioinformatic approach on transcriptome data pertaining to human lung epithelial cells infected with SARS-CoV-2.

21 Dec 2020

Study finds how macrophages may contribute to a therapeutic weak spot in breast cancer

Breast cancer, the second most common cancer in the United States, can result from a number of cellular misregulations, such as deficiencies in the DNA-repairing breast cancer gene, BRCA.

18 Dec 2020

MFCR awards new grants to support an emerging approach to cancer therapeutics

The Mark Foundation for Cancer Research has awarded five new grants in support of an important, emerging approach to cancer therapeutics.

17 Dec 2020

A protein may be responsible for triggering lung scarring in scleroderma patients

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

17 Dec 2020

Lipid mediators can enhance regeneration of inflamed periodontal tissue

Maresin and resolvin, produced by the body from omega-3 fatty acids, can help repair tissue damaged by periodontal disease.

16 Dec 2020

Researchers identify new immune cell that acts as major driver of breast cancer growth

Breast cancer is the most common cancer in women worldwide, but many immunotherapies have had limited success in treating aggressive forms of the disease.

16 Dec 2020

Genomic and immune indicators can help identify prostate cancer patients at high risk of lethal outcomes

Prostate cancer is one of the most common cancers among men in the United States. One in nine men will be diagnosed during his lifetime.

15 Dec 2020

Study: Flavoring chemicals of e-cigarette vapor alone can measurably damage the lungs

Known for their appetizing flavors, such as bubblegum, banana and strawberry, e-cigarettes continue to grow in popularity around the world. Promoted by makers as a "healthy" alternative to regular tobacco cigarettes, researchers are finding e-cigarettes, or vaping, still result in injury to the lungs.

15 Dec 2020

Research reveals insights into potential drivers of 'wet' age-related macular degeneration

"Wet" age-related macular degeneration (AMD) is one of the most common causes of irreversible vision loss in the elderly, and it occurs when abnormal and leaky blood vessels form in the retina, in part due to inflammation.

11 Dec 2020

SARS-CoV-2 spike protein mediates acute lung pathology in mice

A study shows that the viral spike protein is adequate by itself to induce macrophage activation in pulmonary tissue and induce acute inflammation.

10 Dec 2020

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

A new study published on the preprint server bioRxiv in December 2020 reveals the role played by certain genetic factors in this group, in particular the FASLG gene belonging to the tumor necrosis factor (TNF) family.

8 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

Macrophage News and Research

Further Reading

Novel imaging method reveals in vivo localization of antibiotics in infected lung tissues

Gut cells alert the body to danger during parasite invasion

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Study provides new insights into the molecular underpinnings of Duchenne muscular dystrophy

COVID-19: Meta-analysis unveils adversely affected biological processes in infected lung cells

Study finds how macrophages may contribute to a therapeutic weak spot in breast cancer

MFCR awards new grants to support an emerging approach to cancer therapeutics

A protein may be responsible for triggering lung scarring in scleroderma patients

Lipid mediators can enhance regeneration of inflamed periodontal tissue

Researchers identify new immune cell that acts as major driver of breast cancer growth

Genomic and immune indicators can help identify prostate cancer patients at high risk of lethal outcomes

Study: Flavoring chemicals of e-cigarette vapor alone can measurably damage the lungs

Research reveals insights into potential drivers of 'wet' age-related macular degeneration

SARS-CoV-2 spike protein mediates acute lung pathology in mice

FASLG gene may drive cytokine-linked adverse COVID-19 outcomes with age

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Lung tissue analysis reveals promising molecular target to ameliorate pulmonary fibrosis

Study provides mechanistic insights about the role of neutrophils in psoriasis pathogenesis

Vaccination against tuberculosis has influence on the epidemiology of COVID-19

Can melatonin help prevent severe COVID-19?

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