Proteome News and Research

RSS

The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Proteins found that could be used to improve diagnosis of hepatocellular carcinoma

Researchers report in the October 2007 issue of Molecular & Cellular Proteomics that they have identified proteins that could be used to improve the diagnosis of hepatocellular carcinoma, the most common type of liver cancer.

8 Oct 2007

Call for EU to launch major project to map out all our proteins

Biologists still have no clear idea how many active genes there are coding for proteins in humans and other organisms, even though for some species the genomes have been completely sequenced.

26 Jul 2007

Powerful proteomics research promises to revolutionize biomedical discovery

Human cells function through the concerted action of thousands of proteins that control their growth and differentiation.

20 Jul 2007

Simple bladder cancer test

University of Florida researchers have identified a set of proteins that appear to signal the presence of bladder cancer, a discovery they hope will lead to a simple, fast and noninvasive test that can detect the disease early.

9 Jul 2007

Role of environmental factors in the development of Parkinson's disease

Scientists at the Buck Institute for Age Research have shown that combining two environmental toxic substances accelerated age-related degeneration in neurons associated with Parkinson's disease (PD) in mice.

27 Jun 2007

Snake venom medication

A chemist at the Vienna University of Technology (TU Vienna) is looking for unusual structures in snake venom and plans to prove their medical effectiveness.

16 Jun 2007

Study finds large number of new proteins implicated in Huntington's disease

Researchers from four organizations have identified more than 200 new proteins that bind to normal and mutant forms of the protein that causes Huntington's disease (HD).

11 May 2007

New dynamic view of protein dynamics

Scientists from the Institute for Research in Biomedicine (IRB Barcelona), the Life Sciences Programme at the Barcelona Supercomputing Center (BSC) and the National Institute for Bioinformatics (INB) have published a provisional "atlas" of the dynamic behaviour of proteins in the prestigious scientific journal, Proceedings of the National Academy of Sciences.

9 Jan 2007

An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling

Using a combination of enzyme activity and metabolite profiling, we determined that this protein-whose function was previously unknown-serves as a key regulator of a lipid signaling network that contributes to cancer," said Benjamin F. Cravatt, a Scripps Research professor and a member of its Skaggs Institute for Chemical Biology who led the study.

20 Oct 2006

New blood test picks up early breast cancer

A new blood test has been developed by an international team of scientists which can detect the very early stage of breast cancer.

7 Aug 2006

Improving your diet may not help you beat stress

New research shows that some dietary interventions may not prove effective in helping tackle stress and poor health.

10 Jul 2006

Scientists map the entire active protein inventory in cells

Scientists have shown how cutting-edge methods can be used to catalogue the entire inventory of active proteins in cell organelles at a particular moment. Their work sheds considerable light on how cells use proteins.

29 May 2006

Proteomics yields new drug targets for treating cardiogenic shock

When it comes to cell signaling and bioregulation, it's tough to find a more important molecule than nitric oxide (NO). Dysfunction of NO-mediated signaling is thought to be a culprit in lethal cardiovascular conditions such as angina, and septic, cardiogenic and hemorrhagic shock; it may play a role in many other illnesses as well.

3 Apr 2006

University of Michigan Medical School to study the science of obesity and metabolism

As millions of Americans prepare their New Year’s resolutions to lose weight, eat better or exercise more, the University of Michigan Medical School is launching a new center that may help explain why so many resolutions fail, while others succeed.

29 Dec 2005

Robotic microbial protein analysis

Microorganisms have potential as living factories for manufacturing drugs and biochemical products. Rapid mass screening methods are needed to identify new species. A new robotic system also provides useful data for genetic engineering.

15 Dec 2005

The glow points the way: coupled enzyme test helps in the search for the right biocatalyst

The chemical industry is going biological: the use of biocatalysts, called enzymes, allows many products to be prepared very efficiently, economically, and in an environmentally safe manner.

From The University of Manchester 14 Dec 2005

Lupus discovery may improve treatment

Researchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic code" in lupus patients and thus improve treatment.

7 Nov 2005

Researchers characterize the proteome of the human cornea

In doing so, they have identified 141 distinct proteins, 99 of which had not been previously recognized in mammalian corneas. The details of their findings appear in the August/September issue of Molecular and Cellular Proteomics, an American Society for Biochemistry and Molecular Biology journal.

1 Aug 2005

Faster, more accurate diagnostic test for Sjogren's syndrome

Researchers in Japan are developing a faster, more accurate diagnostic test for Sjögren’s (SHOW-grins) syndrome, an incurable autoimmune disorder characterized by chronically dry eyes and dry mouth.

11 Apr 2005

Micro-organisms in clouds could play a crucial role in the spread of disease

The radical theories about nanobacteria – micro-organisms considerably smaller than ordinary bacteria - in clouds are published in two recent articles in the Journal of Proteome Research by Dr Andrei P. Sommer of the University of Ulm, Germany, and Professor Chandra Wickramasinghe of Cardiff University, UK.

6 Apr 2005