Pathophysiology News and Research

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Study reveals factors linked to the development of Crohn's disease

How cells talk to each other, and what they say, has long held fascination for Seema Khurana, professor of biology and biochemistry.

5 Oct 2018

Alnylam announces positive results from Phase 1/2 study of lumasiran for treating primary hyperoxaluria-1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today updated positive results from its Phase 1/2 clinical study of lumasiran, an investigational, subcutaneously administered RNAi therapeutic targeting glycolate oxidase for the treatment of primary hyperoxaluria type 1.

4 Oct 2018

Tomocube introduces new holotomography microscope for live cell imaging

A novel optical microscope utilizing diffraction tomography to generate 3D holographic images of unlabelled live cells is now available from Tomocube. Called HT-1, the new microscope delivers quantitative nanoscale, real-time, dynamic images of individual living cells quickly and simply without any sample preparation.

From Tomocube Inc. 25 Sep 2018

Human-oriented perspective needed to better understand Parkinson's disease

Analysis published in Drug Discovery Today reveals the gap between animal models of Parkinson's disease and our understanding of the neurodegenerative processes underlying the disease, and calls for the implementation of modern, human biology-based technologies to better understand pathological processes and improve treatment outcome.

25 Sep 2018

AGA partners with ESNM for 2019 Gut Microbiota for Health World Summit

The American Gastroenterological Association is proud to partner with the European Society of Neurogastroenterology and Motility for the 8th annual Gut Microbiota for Health World Summit.

24 Sep 2018

Medical cannabis provides relief across dozens of health symptoms, study shows

Utilizing new mobile application technology, researchers at The University of New Mexico found that medical cannabis provides immediate symptom relief across dozens of health symptoms with relatively minimal negative side effects.

11 Sep 2018

World Sepsis Day

A series of articles and thought leader interviews for World Sepsis Day on the 10th September 2018, aiming to raise awareness and improve understanding.

10 Sep 2018

Researchers study motor, cognitive effects of DBS in patients with Parkinson's disease

Researchers from Charité - Universitätsmedizin Berlin have studied motor and cognitive effects of deep brain stimulation in patients with Parkinson's disease.

28 Aug 2018

BrainsWay receives FDA clearance for Deep TMS system to treat adults with obsessive-compulsive disorder

BrainsWay Ltd., the parent company of BrainsWay USA, Inc., and a global leader in the advanced non-invasive treatment of brain disorders, today announces that it has received De Novo clearance from the U.S. Food and Drug Administration (FDA) for its deep transcranial magnetic stimulation (Deep TMS) system for the treatment of obsessive-compulsive disorder (OCD) in adults.

22 Aug 2018

Individuals with synovitis may have greater risk for cartilage damage, shows study

In an Arthritis & Rheumatology study of 221 patients with knee osteoarthritis and meniscal tears, increases in inflammation of the synovial membrane--whether persistently extensive or intermittent--were linked with cartilage damage over time.

22 Aug 2018

Researchers receive multi-million-dollar grant to expand kidney research

Researchers at University of California San Diego School of Medicine and the University of Alabama at Birmingham School of Medicine have received renewed grant funding from the National Institute of Diabetes and Digestive and Kidney Diseases to expand research into the areas of acute kidney failure and acute kidney injuries.

21 Aug 2018

Revolutionary HT microscopy opens new era for label-free 3D imaging of living cells

A spin-out company from the renowned Korea Advanced Institute of Science and Technology in Daejeon has been established to commercialize the revolutionary Holotomography microscopy developed there by Professor YongKeun (Paul) Park.

From Tomocube Inc. 21 Aug 2018

$New algorithm helps identify and manage diabetic patients at increased fracture risk$

New algorithm helps identify and manage diabetic patients at increased fracture risk

Fragility fractures are a serious yet neglected complication of both type 1 and type 2 diabetes, with increased risk of fragility fractures in people with diabetes extending across the life span.

17 Aug 2018

Distinct origin of ADHD identified In children with history of traumatic brain injury

According to a study in Biological Psychiatry, physical brain injury in children contributes to the development of attention-deficit/hyperactivity disorder (ADHD), distinct from genetic risk for the disorder.

14 Aug 2018

Scientists develop simple, innovative method to convert white fat to brown fat

Brown fat tissue in the body can burn enormous amounts of energy to generate heat, and studies in humans and animals have suggested that increasing the amount of healthy brown fat might help weight management and reduce symptoms of diabetes.

2 Aug 2018

New research reveals how gut bacteria and lipid metabolism may affect AD, other brain diseases

BIOCRATES Life Sciences AG, a global leader in targeted metabolomics, reported today the Alzheimer’s Disease Metabolomics Consortium’s new breakthrough in Alzheimer’s research, which connects the Gut-Liver-Brain axis in the development and progression of Alzheimer’s disease (AD). During the Alzheimer’s Association International Conference, Chicago, USA, researchers reported new data on how gut bacteria and lipid metabolism may influence AD.

26 Jul 2018

Initiation of early treatment in HIV-infected infants has undeniable benefits

The initial findings of the ANRS CLEAC study coordinated by Pierre Frange (Hôpital Necker - AP-HP), help define the immunological and virological benefits of early antiretroviral therapy in HIV-infected children living in France.

25 Jul 2018

SUSU scientists find alternative method to treat post-traumatic stress disorder syndrome

In spite of high level of modern medicine development many problems of this sphere are not solved till the present.

18 Jul 2018

Early childhood adversity increases sensitivity of the body's immune response to cocaine

Childhood adversity permanently alters the peripheral and central immune systems, increasing the sensitivity of the body's immune response to cocaine, reports a study by researchers at the IRCCS Santa Lucia Foundation and University of Rome "La Sapienza", Italy.

17 Jul 2018

Researchers detect presence of IgE antibodies after kidney transplantation

Many donor kidneys that are transplanted are rejected by the recipient within ten years after transplantation.