Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Diabetes is rapidly increasing globally, and Asian Indians have the highest prevalence

The incidence of type 2 diabetes is rising, especially in urbanized parts of the world where sedentary lifestyles and obesity abound.

1 Mar 2008

Copy number variation may stem from replication misstep

Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic "template," said researchers at Baylor College of Medicine in Houston in a report that appears today in the journal Cell.

28 Dec 2007

New research alters concept of how circadian clock functions

Scientists from the University of Cambridge have identified a molecule that may govern how the circadian clock in plants responds to environmental changes.

14 Dec 2007

Neurofibromatosis 1 gene drives pivotal decision in early brain development

A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers at Washington University School of Medicine in St. Louis have found.

14 Nov 2007

Lungs' pressure needn't threaten heart transplant survival

Heart surgeons at Johns Hopkins say people who need heart transplants can largely avoid transplant failure due to elevated blood pressure in their lungs with the help of proper drug treatment.

6 Nov 2007

Adenoscan patent lawsuits settled

Astellas Pharma Inc., King Pharmaceuticals, Inc. and Teva Pharmaceutical Industries Ltd. have announced that U.S. subsidiaries of Astellas, along with Item Development AB and King have executed settlement agreements with one of Teva's subsidiaries on lawsuits filed in the United States against Teva's subsidiaries regarding their submission of an abbreviated new drug application (ANDA) for a generic version of Adenoscan (adenosine injection), a pharmacologic stress agent.

22 Oct 2007

Existing drugs may be useful in treating brain tumors

Scientists have shown how developing brain tumors can turn an encounter with a signaling molecule from a fatal experience for the tumor cells into a cue for their own growth and multiplication.

17 Oct 2007

Picking the right stress test for heart disease risk analysis

Stress tests are good front-line tests indicators of heart disease, but just how good depends on ordering the right one, researchers say.

12 Oct 2007

Researchers track how a single molecule of RNA or DNA unwinds

The process by which genes are duplicated is mysterious and complex, involving a cast of characters with diverse talents and the ability to play well with others in extremely close quarters.

27 Jul 2007

Schering-Plough announces licensing of Acadesine

Schering-Plough Corporation has announced the worldwide licensing of acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA), from PeriCor Therapeutics, Inc., a privately held, specialty biopharmaceutical company.

20 Jul 2007

Coffee protects against involuntary eye spasm

People who drink coffee are less likely to develop an involuntary eye spasm called primary late onset blepharospasm, which makes them blink uncontrollably and can leave them effectively ‘blind', according to a study published online ahead of print in the Journal of Neurology Neurosurgery and Psychiatry .

20 Jun 2007

Theophylline offers relief for unexplained chest pain

The discomfort caused by esophageal (non-cardiac) chest pain is often severe, driving many patients to emergency rooms and physicians' offices despite the fact that the ailment has no definable pathology.

10 May 2007

Research paves the way for new therapies designed to manage heart disease in older population

Ischaemic heart disease, characterised by reduced blood flow to the heart, is Australia's and the world's leading cause of death.

4 May 2007

Submission of NDA for Istradefylline(KW-6002), an investigational anti-Parkinson's disease drug

Kyowa Hakko Kogyo Co. has announced that Kyowa Pharmaceutical, Inc., its wholly owned U.S subsidiary, submitted on April 25, 2007 a new drug application (NDA) to the U.S. Food and Drug Administration (FDA) for Istradefylline(KW-6002), its investigational drug for Parkinson's disease.

30 Apr 2007

Humans should try to increase melatonin consumption through food

The Spanish Ageing Research Network (Red Nacional de Investigaci'n del Envejecimiento), funded by Carlos III Health Institute and headed by professor Dario Acuna Castroviejo, from the University of Granada, is very near to achieving one of today's Science greatest goals: allowing humans to age in the best possible health conditions.

25 Apr 2007

Discovery of molecular mechanism that alters strength of higher brain network connections

Yale School of Medicine and University of Crete School of Medicine researchers report in Cell April 20 the first evidence of a molecular mechanism that dynamically alters the strength of higher brain network connections.

21 Apr 2007

Researchers finds meth receptor that could lead to therapy

A recently discovered signaling system in the brain has just been shown to be turned on by methamphetamine, an Oregon Health & Science University study found.

19 Apr 2007

Advances in clinical cardiology

Three studies being presented at the American College of Cardiology's Innovation in Intervention: i2 Summit 2007 in New Orleans, La., highlight the breadth of research propelling advances in clinical cardiology.

3 Apr 2007

What makes a simple biological clock tick?

An interdisciplinary team of researchers at Vanderbilt University has analyzed the simplest known biological clock and figured out what makes it tick.