Neuroscience News and Research

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Scientists describe network map of genes involved in pain perception

Scientists in Australia and Austria have described a "network map" of genes involved in pain perception, with remarkable similarity from fruit flies to people. The work should help identify new analgesic drugs.

7 Dec 2012

Study reveals dual role for Norrin/Frizzled-4 protein pair

Working with mice, Johns Hopkins researchers have shed light on the activity of a protein pair found in cells that form the walls of blood vessels in the brain and retina, experiments that could lead to therapeutic control of the blood-brain barrier and of blood vessel growth in the eye.

7 Dec 2012

BDNF molecule appears to play a direct role in regulation of blood pressure

Researchers at Oregon Health & Science University's School of Dentistry have made an important connection between a molecule critical to nerve cells and high blood pressure. Production of the molecule Brain-Derived Neurotrophic Factor (BDNF) appears to increase dramatically in blood pressure-sensing nerve cells during hypertension.

7 Dec 2012

Kessler Foundation to study effects of intellectual enrichment on cognitive decline in people with MS

The National Multiple Sclerosis (MS) Society awarded Victoria Leavitt, Ph.D., a $44,000 grant to study the effects of intellectual enrichment on cognitive decline in individual with multiple sclerosis.

7 Dec 2012

Scientists identify key molecular pathway that leads to depression

Scientists have identified the key molecular pathway leading to depression, revealing potential new targets for drug discovery, according to research led by King's College London's Institute of Psychiatry. The study, published today in Neuropsychopharmacology, reveals for the first time that the 'Hedgehog pathway' regulates how stress hormones, usually elevated during depression, reduce the number of brain cells.

6 Dec 2012

Scientists develop MitoFish for in vivo studies of mitochondria transport in nerve cells

Scientists have demonstrated a new way to investigate mechanisms at work in Alzheimer's and other neurodegenerative diseases, which also could prove useful in the search for effective drugs. For new insights, they turned to the zebrafish, which is transparent in the early stages of its life. The researchers developed a transgenic variety, the "MitoFish," that enables them to see - within individual neurons of living animals - how brain diseases disturb the transport of mitochondria, the power plants of the cell.

6 Dec 2012

TSRI scientist to better define how brain organizes different types of memories among neurons

A scientist from the Florida campus of The Scripps Research Institute (TSRI) has been awarded approximately $2.5 million from the National Institute of Neurological Disorders and Stroke to better define how the brain organizes different types of memories among its neurons.

6 Dec 2012

New method can generate stable human mesenchymal stem cells for bone engineering

Human mesenchymal stem cells (hMSCs) can develop into bone cells and are useful for tissue engineering and regeneration. However, when grown in the laboratory they quickly lose their ability to continue dividing and they die.

5 Dec 2012

New method promises to boost stem cell production in laboratory

A new method for generating stem cells from mature cells promises to boost stem cell production in the laboratory, helping to remove a barrier to regenerative medicine therapies that would replace damaged or unhealthy body tissues.

5 Dec 2012

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

AstraZeneca today announced the presentation of important new data from studies of FASLODEX (fulvestrant) Injection at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium taking place from 4-8 December at the Henry B. Gonzalez Convention Center, San Antonio, Texas.

5 Dec 2012

Mainz University neuroscientist professor receives ERC Advanced Grant

The European Research Council (ERC) has earmarked some EUR 2.5 million to fund research being conducted by neuroscientist Professor Dr. Robert Nitsch at the Mainz University Medical Center.

5 Dec 2012

psi-GSH prevents neurodegeneration associated with Alzheimer's in mouse model

Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.

4 Dec 2012

Swedish Medical Center/First Hill named among Leapfrog Group's 2012 Top Hospitals

The Leapfrog Group's annual class of 'Top Hospitals' – just 89 from a field of nearly 1,200 – will be announced today in Baltimore, Md., and includes Swedish Medical Center/First Hill for the third year in a row. The announcement will take place at Leapfrog's Annual Meeting.

4 Dec 2012

Link between stress and brain activation in patients with seizure

A study reported here at the 66th American Epilepsy Society Annual Meeting has identified a significant difference in the brain response to stress in patients who believe stress is an important factor in their seizure control compared to patients who do not hold this belief.

4 Dec 2012

Merck commences MK-8931 Phase II/III trial in Alzheimer's

Merck, known as MSD outside the United States and Canada, announced it has started a Phase II/III clinical trial designed to evaluate the safety and efficacy of MK-8931 versus placebo in patients with mild-to-moderate Alzheimer's disease.

3 Dec 2012

Childhood trauma can leave permanent epigenetic marks on DNA

Abused children are at high risk of anxiety and mood disorders, as traumatic experience induces lasting changes to their gene regulation. Scientists from the Max Planck Institute of Psychiatry in Munich have now documented for the first time that genetic variants of the FKBP5 gene can influence epigenetic alterations in this gene induced by early trauma.

3 Dec 2012

Scientists discover how humans and mammals develop intelligence

Scientists have discovered for the first time how humans - and other mammals - have evolved to have intelligence.

3 Dec 2012

Researchers find association between neuroscience providers and stroke-related deaths in US

Researchers at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire, have found an association in the United States between a higher density of neurologists and neurosurgeons and a decreased risk of death from stroke.

1 Dec 2012

NCQA accredits Jefferson Medical Care - South Philadelphia as Patient-Centered Medical Home

Jefferson Medical Care - South Philadelphia, a primary care practice, has received accreditation from the National Committee for Quality Assurance (NCQA) as a Patient-Centered Medical Home, showing its commitment to evidence-based, patient-centered care that focuses on coordinated and long-term collaborative patient-physician partnerships.

1 Dec 2012

Brain study provides new insights into how recognition is connected with emotion and morality

People are able to detect, within a split second, if a hurtful action they are witnessing is intentional or accidental, new research on the brain at the University of Chicago shows.

1 Dec 2012

Neuroscience News and Research

Scientists describe network map of genes involved in pain perception

Study reveals dual role for Norrin/Frizzled-4 protein pair

BDNF molecule appears to play a direct role in regulation of blood pressure

Kessler Foundation to study effects of intellectual enrichment on cognitive decline in people with MS

Scientists identify key molecular pathway that leads to depression

Scientists develop MitoFish for in vivo studies of mitochondria transport in nerve cells

TSRI scientist to better define how brain organizes different types of memories among neurons

New method can generate stable human mesenchymal stem cells for bone engineering

New method promises to boost stem cell production in laboratory

New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC

Mainz University neuroscientist professor receives ERC Advanced Grant

psi-GSH prevents neurodegeneration associated with Alzheimer's in mouse model

Swedish Medical Center/First Hill named among Leapfrog Group's 2012 Top Hospitals

Link between stress and brain activation in patients with seizure

Merck commences MK-8931 Phase II/III trial in Alzheimer's

Childhood trauma can leave permanent epigenetic marks on DNA

Scientists discover how humans and mammals develop intelligence

Researchers find association between neuroscience providers and stroke-related deaths in US

NCQA accredits Jefferson Medical Care - South Philadelphia as Patient-Centered Medical Home

Brain study provides new insights into how recognition is connected with emotion and morality

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