Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality globally, exhibits a dismal five-year survival rate of only 18%.

2 Jul 2024

Pharmacogenomics: A pathway to personalized treatment in prostate cancer

Prostate cancer (PC) stands as the second leading cause of death among American men, with about 1 in 8 men diagnosed during their lifetime.

2 Jul 2024

Ethanolic extracts from olive leaves show promise in combating cancer and infections

A recent study in Antioxidants reveals that ethanolic extracts from Greek and Spanish olive leaves exhibit high antioxidant, antimicrobial, and anticancer properties, with Greek extracts showing greater efficacy. This suggests potential healthcare applications, particularly as antimicrobial agents and melanoma treatments.

30 Jun 2024

Moffitt scientists develop breakthrough method for scalable synthesis of withanolides

Withanolides, a class of naturally occurring compounds found in plants, have long been a focus of cancer research due to their ability to inhibit cancer cell growth, induce cell death and prevent metastasis.

28 Jun 2024

Microscopic changes in the liver can be used to predict pancreatic cancer spread

Microscopic changes in the liver can be used to predict if, and where, pancreatic cancer may spread in the body.

28 Jun 2024

Using liver biopsies to identify predictors of pancreatic cancer metastasis

Researchers at Weill Cornell Medicine with an international team have used liver biopsies to identify cellular and molecular markers that can potentially be used to predict whether and when pancreatic cancer will spread to an individual's liver or elsewhere, such as the lung.

28 Jun 2024

PFDN6 protein could be a new target for colorectal cancer treatment

Researchers have identified a protein called PFDN6 that may play a role in the development and spread of colorectal cancer (CRC).

27 Jun 2024

Melanoma messages: Social media a useful tool for skin cancer communication

Researchers assessed health communication messages that effectively educate the public and raise intentions to get skin exams.

26 Jun 2024

Weill Cornell Medicine receives $1.5M grant to predict prostate cancer bone metastasis

Weill Cornell Medicine received a $1.5 million grant from the U.S. Department of Defense Prostate Cancer Research Program to develop new approaches for predicting the spread of cancer cells to the bone in men with prostate cancer, using tumor samples taken at early stages of the disease.

25 Jun 2024

Open-source platform enables high-definition spatial transcriptomics

An open-source platform developed by researchers in Nikolaus Rajewsky's lab at the Max Delbrück Center creates molecular maps from patient tissue samples with subcellular precision, enabling detailed study and potentially enhancing routine clinical pathology. The study was published in "Cell."

25 Jun 2024

New insights into signaling pathways and resistance mechanisms in colorectal cancer

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. The complexity of its pathogenesis, involving genetic mutations, dysregulated signaling pathways, and compromised immune surveillance, presents significant challenges for effective treatment.

21 Jun 2024

New challenges in cancer care: cardiovascular disease and environmental factors

Preclinical and epidemiologic evidence linking air pollution to cardio-oncology.

21 Jun 2024

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system.

20 Jun 2024

Timing of melanoma metastasis: Critical implications for treatment

A new research perspective was published in Oncotarget's Volume 15 on June 13, 2024, entitled, "When does a melanoma metastasize? Implications for management."

18 Jun 2024

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors.

12 Jun 2024

Gut bacteria turn dietary phytate into health-boosting fatty acids, study shows

Study reveals that human gut bacteria, particularly Mitsuokella jalaludinii, efficiently degrade dietary phytate into short-chain fatty acids, enhancing health benefits through microbial synergy.

12 Jun 2024

SU2C-SARC032 trial: Immunotherapy reduces relapse risk in soft tissue sarcoma by 43%

For the last three decades, breakthroughs have been sparse for soft tissue sarcomas, which are rare cancers that affect muscles, fat and other connective tissues.

4 Jun 2024

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Tumor cells often hijack normal physiological processes to support their growth, exploiting proteins that are in charge of essential cell functions.

29 May 2024

Phase 1 trial for EBC-129 progresses into dose expansion

The Experimental Drug Development Centre (EDDC), Singapore's national platform for drug discovery and development, is pleased to announce that the Phase 1 trial for EBC-129 has progressed into dose expansion.

24 May 2024

In-vivo imaging to quantify collagen morphology in preclinical melanoma models during immunotherapy

Collagen, a major component of the extracellular matrix, plays a crucial role in tumor development.

23 May 2024

Metastasis News and Research

Further Reading

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Pharmacogenomics: A pathway to personalized treatment in prostate cancer

Ethanolic extracts from olive leaves show promise in combating cancer and infections

Moffitt scientists develop breakthrough method for scalable synthesis of withanolides

Microscopic changes in the liver can be used to predict pancreatic cancer spread

Using liver biopsies to identify predictors of pancreatic cancer metastasis

PFDN6 protein could be a new target for colorectal cancer treatment

Melanoma messages: Social media a useful tool for skin cancer communication

Weill Cornell Medicine receives $1.5M grant to predict prostate cancer bone metastasis

Open-source platform enables high-definition spatial transcriptomics

New insights into signaling pathways and resistance mechanisms in colorectal cancer

New challenges in cancer care: cardiovascular disease and environmental factors

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Timing of melanoma metastasis: Critical implications for treatment

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Gut bacteria turn dietary phytate into health-boosting fatty acids, study shows

SU2C-SARC032 trial: Immunotherapy reduces relapse risk in soft tissue sarcoma by 43%

Novel method creates antibody-peptide inhibitor conjugates with enhanced therapeutic efficacy

Phase 1 trial for EBC-129 progresses into dose expansion

In-vivo imaging to quantify collagen morphology in preclinical melanoma models during immunotherapy

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