Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Positive results from levomilnacipran Phase III study for major depressive disorder

Forest Laboratories, Inc. and Pierre Fabre Medicament today announced preliminary top-line results from a Phase III study of levomilnacipran for the treatment of adults with major depressive disorder (MDD).

18 Jul 2011

New antidepressant prescription linked to increased risk of falls in nursing home residents

Nursing home residents taking certain antidepressant medications are at an increased risk of falling in the days following the start of a new prescription or a dose increase of their current drug, according to a new study by the Institute for Aging Research of Hebrew SeniorLife, an affiliate of Harvard Medical School.

16 Jul 2011

Regular exercise may help prevent panic and related disorders

Regular exercise may be a useful strategy for helping prevent the development of panic and related disorders, a new study suggests.

13 Jul 2011

Research roundup: Rural hospitals have poorer quality; Cost-effective migraine relief; Doctors still take Medicare

Quality Of Care And Patient Outcomes In Critical Access Rural Hospitals -- This study looks at the quality of care provided by patterns of care at "critical access hospitals," a federal designation for hospitals that serve rural populations and thus have been granted special incentives under Medicare.

8 Jul 2011

Antidepressants during first trimester linked to increased risk of autism

Prenatal exposure to selective serotonin reuptake inhibitors, especially during the first trimester, is associated with a modest increase the risk of developing an autism spectrum disorder, according to a report published Online First in the Archives of General Psychiatry, one of the JAMA/Archives journals.

5 Jul 2011

Some drug mixtures may be fatal for elderly: study

British scientists warn that well known brands of hay fever tablets, painkillers and sleeping pills pose a previously unknown threat to elderly people’s health when taken together. Many are available over the counter at pharmacies as well as being prescribed by GPs, nurses and chemists they said.

23 Jun 2011

Enrollment complete in Rexahn's Serdaxin Phase IIb clinical trial for major depressive disorder

Rexahn Pharmaceuticals, Inc., a clinical stage pharmaceutical company developing and commercializing potential best in class oncology and CNS therapeutics, today announced that it has completed enrollment in its Phase IIb clinical trial of Serdaxin to treat major depressive disorder (MDD).

22 Jun 2011

Naurex commences GLYX-13 Phase II trial in treatment-resistant depression

Naurex Inc., a clinical-stage company developing innovative treatments to address unmet needs in psychiatry and neurology, today announced that it has initiated a Phase II clinical trial of its lead compound GLYX-13.

22 Jun 2011

One in ten Europe's middle-aged citizens took antidepressants during 2010

New research from the University of Warwick and the IZA Institute in Bonn shows that 10% of middle-aged Europeans took antidepressants in 2010. The researchers looked in detail at the lives of a randomly selected sample of nearly 30,000 Europeans. The study covered 27 countries.

20 Jun 2011

Fast-acting antidepressant effect of ketamine

UT Southwestern Medical Center scientists are shedding new light on why the anesthetic drug ketamine produces a fast-acting antidepressant response in patients with treatment-resistant depression.

17 Jun 2011

Study finds no link between anxiety, depression and weight loss after bariatric surgery

Depression and anxiety do not seem to interfere with the amount of weight loss or the improvement of obesity-related conditions after bariatric surgery, according to a new study of more than 25,000 patients presented here at the 28th Annual Meeting of the American Society for Metabolic & Bariatric Surgery.

16 Jun 2011

Brain research funds crisis: Report

According to the European College of Neuropsychopharmacology there is a dramatic drop in private and public funding for research in brain diseases that has led to a “withdrawal of hope” for millions of sufferers and could delay the search for treatments and cures by 30 years.

16 Jun 2011

Alkermes commences ALKS 5461 phase 1/2 study for treatment-resistant depression

Alkermes, Inc. today announced the initiation of a phase 1/2 study of ALKS 5461 for treatment-resistant depression (TRD). ALKS 5461 is the combination of ALKS 33, a proprietary opioid modulator, and buprenorphine. TRD, which is also known as refractory depression, refers to depressive episodes that are not adequately controlled by standard antidepressant therapy.

15 Jun 2011

New findings from Deplin clinical trial on major depressive disorder presented at NCDEU

New findings from a multi-center, randomized, placebo-controlled clinical study of Deplin 15mg added to commonly prescribed antidepressants known as selective serotonin reuptake inhibitors showed that all patients who achieved remission at 30 days using Deplin 15mg adjuvant therapy, and who chose to enter a 12 month maintenance phase, maintained their remission after a year of treatment.

14 Jun 2011

Survey reveals increase in drinking, cannabis use and psychological distress

The latest survey of Ontario adults from the Centre for Addiction and Mental Health (CAMH) shows increasing rates of daily drinking and cannabis use and high levels of psychological distress. The results of the 2009 CAMH Monitor survey, the longest running survey tracking mental health and addiction indicators among adults in Ontario, were published today.

13 Jun 2011

New neurons may take over six months to mature

New neurons take more than six months to mature in adult monkeys and that time is likely even longer in humans, according to researchers at the University of Pittsburgh School of Medicine, the University of Illinois, and Pennsylvania State University.

8 Jun 2011

Women with higher leptin levels have fewer symptoms of depression

Women who have higher levels of the appetite-controlling hormone leptin have fewer symptoms of depression, and this apparent inverse relationship is not related to body mass index (BMI), a new study finds.

7 Jun 2011

Dr. Reddy’s launches generic ARICEPT, EFFEXOR XR and FEMARA in the US

Dr. Reddy's Laboratories today announced that it has launched three products in the US market.

6 Jun 2011

GP journal focuses on mental health

Australian Family Physician, the flagship journal of The Royal Australian College of General Practitioners (RACGP), features a range of clinical, viewpoint and research articles focusing on key issues in general practice today. The June 2011 edition focuses on mental illness and includes the following feature articles.

6 Jun 2011

Paxil and Pravachol in combination cause unexpected increase in blood glucose levels

A widely used combination of two common medications may cause unexpected increases in blood glucose levels, according to a study conducted at the Stanford University School of Medicine, Vanderbilt University and Harvard Medical School. Researchers were surprised at the finding because neither of the two drugs - one, an antidepressant marketed as Paxil, and the other, a cholesterol-lowering medication called Pravachol - has a similar effect alone.

26 May 2011