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Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain.

3 Apr 2024

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Researchers in Brazil have used an innovative technique in molecular biology to identify targets for candidate vaccines against Schistosoma mansoni, the parasite that causes schistosomiasis.

2 Apr 2024

Research suggests booster doses may be necessary for monkeypox immunity

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows that even in men who receives two doses of mpox vaccine intradermally, their level of antibodies to the virus falls to low or zero within the first few months if they have not received a previous smallpox vaccine.

1 Apr 2024

Study reveals waning antibody response to monkeypox vaccine over time

New research to be presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April) shows that the antibodies produced by Modified Vaccinia virus Ankara - Bavarian Nordic (MVA-BN) vaccination against mpox wane significantly within a year of receiving the vaccination – but in people with pre-existing immunity due to childhood smallpox vaccination in childhood, antibody levels remain high in almost all cases.

1 Apr 2024

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

Study demonstrated that selectively reducing myeloid-biased hematopoietic stem cells (my-HSCs) in aged mice rejuvenated the immune system, enhanced lymphopoiesis, reduced inflammation, and improved responses to viral infection, highlighting a potential strategy for countering age-related immune decline.

31 Mar 2024

DNA repair process key to memory formation, study finds

Study reveals that learning triggers a series of molecular events including DNA damage and repair in hippocampal neurons, mediated by TLR9, crucial for memory formation.

31 Mar 2024

An ActRIIA fusion protein got FDA approved for PAH treatment

On March 26th, the US FDA granted approval for Merck’s WINREVAIR™ (sotatercept-csrk), marking a significant milestone in pulmonary arterial hypertension (PAH) treatment. PAH, characterized by elevated blood pressure in the arteries connecting the heart and lungs, poses a grave risk of heart failure.

From Sino Biological Inc. 28 Mar 2024

Scientists develop an mRNA technology approach to target Alzheimer’s disease

Scientists at The Florey have developed an mRNA technology approach to target the toxic protein tau, which builds up in patients with Alzheimer's disease and other dementias.

28 Mar 2024

Antibody discovery could explain mysteries about COVID-19 and long COVID

UVA Health researchers have discovered a potential explanation for some of the most perplexing mysteries of COVID-19 and long COVID.

28 Mar 2024

Early understanding of diabetes risk could help in better disease management

With diabetes increasing at an alarming rate in the United States, Diabetes Alert Day is meant to be a one-day "wake-up call" to the seriousness of diabetes and the importance of understanding your risk.

28 Mar 2024

Clinical trial to test the feasibility of using at-home cancer immunotherapy

A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.

28 Mar 2024

Researchers discover key drivers behind follicular lymphoma's aggressive transformation

A team led by researchers at Weill Cornell Medicine has identified important drivers of the transformation of a type of blood cancer called follicular lymphoma from a slow-growing form to the aggressive form it takes in some patients.

28 Mar 2024

Longer durations of breastfeeding lowers the risk of childhood cancers

Whether duration of breastfeeding was associated with a lower risk of childhood cancers.

28 Mar 2024

Bio-Rad launches validated antibodies for rare cell and circulating tumor cell enumeration

Antibodies validated for use with Bio-Rad’s Celselect Slides™ enumeration stain kits to enable immunostaining of captured circulating tumor cells in liquid biopsy samples.

From Bio-Rad Laboratories 26 Mar 2024

Researchers identify viable vaccine targets for hepatitis C infections

By studying individuals who spontaneously clear hepatitis C infections, a team of researchers has identified viable vaccine targets for a disease that infects 70 million worldwide with case numbers increasing every year.

26 Mar 2024

Children with multiple sclerosis have better outcomes if treated early and with high-efficacy therapies

A ground-breaking study – the largest of its kind globally – has found children with multiple sclerosis (MS) have better outcomes if treated early and with the same high-efficacy therapies as adults.

25 Mar 2024

Immune responses in mesenteric lymph nodes improve understanding of Crohn's disease

Crohn's disease is a chronic inflammatory bowel disease that is sometimes insufficiently controlled by immunosuppressive therapies with a subsequent need for surgical removal of affected bowel segments.

25 Mar 2024

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Research highlights the inflammatory impacts of ARDS on the heart, underscoring the role of immune responses in cardiovascular complications from viral infections, including COVID-19, and emphasizes the potential of TNF-α neutralizing therapy to mitigate these effects.

24 Mar 2024

Boosting mRNA activity and longevity with multi-tailed structures

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines

22 Mar 2024

Groundbreaking atlas maps over 80 blood stem cell types

Thanks to an unusual application of game theory and machine learning technology, a large team of scientists led by experts at Cincinnati Children's has published the world's most detailed "atlas" of the many types of stem cells and early progenitors involved in producing human blood from diverse donors.

21 Mar 2024

Antibodies News and Research

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

Innovative molecular biology technique used to identify targets for Schistosoma mansoni vaccine candidates

Research suggests booster doses may be necessary for monkeypox immunity

Study reveals waning antibody response to monkeypox vaccine over time

Turning back the clock on aging immune systems: New treatment rejuvenates elderly defenses

DNA repair process key to memory formation, study finds

An ActRIIA fusion protein got FDA approved for PAH treatment

Scientists develop an mRNA technology approach to target Alzheimer’s disease

Antibody discovery could explain mysteries about COVID-19 and long COVID

Early understanding of diabetes risk could help in better disease management

Clinical trial to test the feasibility of using at-home cancer immunotherapy

Researchers discover key drivers behind follicular lymphoma's aggressive transformation

Longer durations of breastfeeding lowers the risk of childhood cancers

Bio-Rad launches validated antibodies for rare cell and circulating tumor cell enumeration

Researchers identify viable vaccine targets for hepatitis C infections

Children with multiple sclerosis have better outcomes if treated early and with high-efficacy therapies

Immune responses in mesenteric lymph nodes improve understanding of Crohn's disease

Heart at risk from ARDS: Inflammatory responses fuel cardiovascular complications

Boosting mRNA activity and longevity with multi-tailed structures

Groundbreaking atlas maps over 80 blood stem cell types

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