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New risk assessment tool developed for predicting outcomes in heart failure patients

UVA Health researchers have developed a powerful new risk assessment tool for predicting outcomes in heart failure patients. The researchers have made the tool publicly available for free to clinicians.

14 May 2024

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease development and treatments for the potentially fatal condition, a study suggests.

14 May 2024

Experts advocate for terminology change in brain injury research

A new editorial published this May in the British Journal of Sports Medicine by experts from Spaulding Rehabilitation, Boston University, Mayo Clinic, and the Concussion Legacy Foundation, argues that the term "subconcussion" is a dangerous misnomer that should be retired.

14 May 2024

Investigational drug shows promise in increasing oxygen uptake for patients with heart condition

People with a common heart condition were able to use significantly more oxygen while exercising after taking an investigational drug in an international clinical trial, according to a study published today in the New England Journal of Medicine.

14 May 2024

New joint guideline highlights importance of coordinated care for peripheral artery disease

Timely diagnosis and proper management of peripheral artery disease (PAD), including coordinated care from a multispecialty team, are essential to help prevent amputation and other cardiovascular complications and to allow patients with PAD to live longer lives with better physical function and improved quality of life, according to a new joint guideline published today in the American Heart Association's flagship, peer-reviewed journal Circulation and simultaneously in the Journal of the American College of Cardiology.

14 May 2024

New study sheds light on interferon combinations' role in lupus variability

In a new study, researchers from Johns Hopkins Medicine say they have uncovered insights as to why lupus symptoms and severity present differently in individuals with the autoimmune condition, which affects up to 1.5 million Americans.

14 May 2024

Zika virus-specific synthetic molecule can differentiate between prior infections with different flaviviruses

A newly discovered Zika virus-specific synthetic molecule is capable of differentiating Zika-immune patient samples from samples of patients previously infected with the related dengue virus.

14 May 2024

Exploring how intense ultrasound can release biological indicators of disease

Ultrasound imaging offers a valuable and noninvasive way to find and monitor cancerous tumors. However, much of the most crucial information about a cancer, such as specific cell types and mutations, cannot be learned from imaging and requires invasive and damaging biopsies.

14 May 2024

Metabolomic analysis sheds light on gut microbes' role in cardiovascular disease risk

The effect of gut bacteria on non-high-density lipoprotein cholesterol (non-HDL-c) variations.

14 May 2024

Ketogenic diet boosts mental health: Study reveals reduced stress and improved mood

A recent study in Nutrition by Northumbria University explored how adherence to a ketogenic diet affects mental health in the general population, finding improvements in calmness, contentedness, alertness, and overall emotional well-being.

14 May 2024

Personalized dietary programs outperform general advice for better heart health

Study found that personalized dietary programs (PDP) led to significant improvements in cardiometabolic health compared to standard dietary advice, with notable reductions in weight, triglyceride levels, and waist circumference.

13 May 2024

Experimental gene therapy shows promise for treating herpes infections

Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus.

13 May 2024

Obesity, metabolic syndrome impact breast cancer subtypes and mortality

In the Women's Health Initiative (WHI) randomized trial, a low-fat diet reduced breast cancer mortality, especially in women with more metabolic syndrome (MetS) components (obesity, high blood pressure, elevated blood sugar, and abnormal cholesterol).

13 May 2024

Aficamten shows promise in enhancing exercise capacity in patients with hypertrophic cardiomyopathy

Even though mortality and hospitalization rates have improved, the quality of life for those living with hypertrophic cardiomyopathy (HCM) can be compromised with limiting symptoms such as exertional dyspnoea and decreased exercise capacity.

13 May 2024

Semaglutide improves heart failure symptoms and reduces loop diuretic dose

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction (HFpEF) regardless of diuretic use, according to late breaking research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology.

13 May 2024

SHINE trial reveals risks of high blood sugar in post-thrombolysis stroke care

An ambitious, nationwide clinical trial led by UVA Health's Karen Johnston, MD, has provided doctors with long-needed insights into the importance of managing stroke patients' blood sugar after treatment with clot-busting therapy.

13 May 2024

Measles vaccine more likely to be completely ineffective in children born by C-section

A study by the University of Cambridge, UK, and Fudan University, China, has found that a single dose of the measles jab is up to 2.6 times more likely to be completely ineffective in children born by C-section, compared to those born naturally.

13 May 2024

Wearable biosensors with skin interfaces for newborn and neonatal health monitoring

Recent improvements in newborn wearable systems, concentrating on skin-interfaced wearables for physiological monitoring across many branches.

13 May 2024

First responders, veterans hail benefits of psychedelic drugs as California debates legalization

Wade Trammell recalls the time he and his fellow firefighters responded to a highway crash in which a beer truck rammed into a pole, propelling the truck's engine through the cab and into the driver's abdomen.

13 May 2024

Aerobic exercise proves most effective for combating obesity-related inflammation

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May), reveals the anti-inflammatory power of moderate-to-vigorous aerobic exercise in adults living with the low-grade inflammation of obesity, shedding light on its potential to help prevent multiple metabolic diseases including type 2 diabetes and atherosclerosis (clogged arteries).

13 May 2024

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Blood News and Research

New risk assessment tool developed for predicting outcomes in heart failure patients

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

Experts advocate for terminology change in brain injury research

Investigational drug shows promise in increasing oxygen uptake for patients with heart condition

New joint guideline highlights importance of coordinated care for peripheral artery disease

New study sheds light on interferon combinations' role in lupus variability

Zika virus-specific synthetic molecule can differentiate between prior infections with different flaviviruses

Exploring how intense ultrasound can release biological indicators of disease

Metabolomic analysis sheds light on gut microbes' role in cardiovascular disease risk

Ketogenic diet boosts mental health: Study reveals reduced stress and improved mood

Personalized dietary programs outperform general advice for better heart health

Experimental gene therapy shows promise for treating herpes infections

Obesity, metabolic syndrome impact breast cancer subtypes and mortality

Aficamten shows promise in enhancing exercise capacity in patients with hypertrophic cardiomyopathy

Semaglutide improves heart failure symptoms and reduces loop diuretic dose

SHINE trial reveals risks of high blood sugar in post-thrombolysis stroke care

Measles vaccine more likely to be completely ineffective in children born by C-section

Wearable biosensors with skin interfaces for newborn and neonatal health monitoring

First responders, veterans hail benefits of psychedelic drugs as California debates legalization

Aerobic exercise proves most effective for combating obesity-related inflammation

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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