Inflammatory Disease News and Research

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Higher dose of pneumococcal vaccine improves antibody response in patients receiving rituximab for ANCA-associated vasculitis

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that a higher dose of pneumococcal vaccine safely and effectively improved antibody response in patients receiving rituximab for ANCA-associated vasculitis.

8 Nov 2022

Microscopic IBD inflammation linked to women's elevated risk of giving birth preterm

Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a University of Gothenburg study shows.

7 Nov 2022

What are the implications of microbial ecosystems for female reproductive health?

Researchers reviewed the current understanding of the composition and temporal dynamics of microbial niches in the female reproductive tract.

31 Oct 2022

Researchers develop new method to calculate the delay of signal propagations in brains of MS patients

Researchers of the Human Brain Project have developed a new methodology to calculate the delay of signal propagations in brains of patients suffering from multiple sclerosis, a chronic inflammatory disease that affects more than 2 million people worldwide.

27 Oct 2022

Study shows a changed microbiome in the lower airways for sarcoidosis patients

Sarcoidosis is a systemic inflammatory disease that is difficult to diagnose and treat, partly because its cause and mechanism remain unclear.

21 Oct 2022

Multiple research platforms identify environmental chemical agents that promote intestinal inflammation

Inflammatory bowel disease (IBD), a condition characterized by chronic gastrointestinal inflammation, is becoming increasingly common in industrialized countries.

21 Oct 2022

Does skin inflammation exacerbate COVID-19?

In a new study, researchers discussed inflammation during infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Oct 2022

Pain-sensing neurons protect the gut from inflammation and associated tissue damage

Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a study from researchers at Weill Cornell Medicine.

14 Oct 2022

Clinical features and outcomes of fulminant myocarditis revealed by nationwide cohort study

Myocarditis is an inflammatory disease of the myocardium often caused by viral infections or autoimmune disorders. Fulminant myocarditis (FM) is a rare and severe presentation of myocarditis characterized by hemodynamically unstable conditions requiring inotropes and/or mechanical circulatory support.

30 Sep 2022

Generating a mutation in key molecules could offer new way to prevent and treat gonorrhea

Creating a mutation that inhibits how the bacterial pathogen Neisseria gonorrhoeae causes gonorrhea, a common sexually transmitted infection, could offer a new way to prevent and treat the disease, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

23 Sep 2022

Duke researchers identify chlamydia’s stealthy cloaking device

Chlamydia, the leading cause of sexually transmitted bacterial infections, evades detection and elimination inside human cells by use of a cloaking device. But Duke University researchers have grasped the hem of that invisibility cloak and now hope they can pull it apart.

9 Sep 2022

Experimental drug protects mice from sudden death due to blood vessel rupture

An experimental drug therapy protects mice from sudden death due to the rupture of a major blood vessel in the abdomen, according to a study from researchers at Washington University School of Medicine in St. Louis.

10 Aug 2022

Integrated community care approach can offer solution to struggling rheumatology services, experts say

As patients wait up to a decade for the diagnosis of life-impacting rheumatic conditions, experts argue that ingrained pressures facing NHS rheumatology services can, and should, be eased with an integrated community care/secondary care approach, rather than a reliance on secondary care alone.

3 Aug 2022

RINVOQ® (upadacitinib) Approved by European Commission as an Oral Treatment for Adults with Active Non-Radiographic Axial Spondyloarthritis

With this approval, RINVOQ® is the first and only Janus Kinase inhibitor approved to treat patients across the spectrum of axial spondyloarthritis (nr-axSpA and ankylosing spondylitis) in the EU.

From AbbVie 29 Jul 2022

Nanotherapeutic compound may help treat inflammation, brain injury in patients with severe COVID-19

An anti-inflammatory compound may have the potential to treat systemic inflammation and brain injury in patients with severe COVID-19 and significantly reduce their chances of death, according to a new study from UTHealth Houston and other institutions.

20 Jul 2022

The impact of glucocorticoid therapy on immune responses to COVID-19 vaccination or infection in rituximab-treated patients with autoimmune disorders

Researchers examined immune reactions to SARS-CoV-2)among B cell-depleted autoimmune patients who concomitantly administered glucocorticoids.

18 Jul 2022

Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

A new study showed that the newly designed oral nano-in-micro hydrogel delivery platform could be efficiently used to deliver curcumin for the treatment of Ulcerative Colitis.

5 Jul 2022

The influence of immunosuppressive therapy on the development of adaptive immunity after SARS-CoV-2 vaccination

Researchers evaluated the impact of immunosuppressive therapies on the induction of adaptive immunity after COVID-19 vaccination.

5 Jul 2022

Researchers identify an epigenetic signature associated to the development of MIS-C after COVID-19

Researchers from the Cancer Epigenetics group led by Dr. Manel Esteller at the Josep Carreras Leukaemia Research Institute and Dr. Aurora Pujol, from the Bellvitge Biomedical Research Institute, have identified an epigenetic signature associated to the development of the Multisystem Inflammatory Syndrome in Children (MIS-C) after a SARS-CoV-2 virus infection.

27 Jun 2022

Study finds higher risk of premature death among patients with pediatric onset immune-mediated inflammatory disease

Patients with a pediatric onset immune-mediated inflammatory disease have a significantly higher risk of premature death, according to new research being presented today at the 54th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition.

26 Jun 2022