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Nicotine is an alkaloid found in the nightshade family of plants (''Solanaceae'') which constitutes approximately 0.6–3.0% of dry weight of tobacco, with biosynthesis taking place in the roots, and accumulating in the leaves.

ERK pathway discovery may provide therapeutic options for treating drug addictions

The extracellular-signal regulated kinase (ERK) pathway plays a role in multiple drug addictions and appears to modulate neuronal plasticity through epigenetic mechanisms, say French scientists.

7 Oct 2013

Time to first cigarette independently predicts lung cancer

The time to first cigarette after waking is an independent risk factor for lung cancer, a Japanese case-control study has found.

27 Sep 2013

Mother who smoke during her pregnancy may transmit asthma to future generation

Asthma is a serious public health problem. An estimated 300 million people worldwide suffer from this sometimes deadly lung disease, a number expected to increase to 400 million by 2025. One well-established risk factor for asthma is having a mother who smoked during her pregnancy.

21 Sep 2013

Depressed smokers may benefit from mood management interventions

Studies have shown that people with depression are about twice as likely to smoke cigarettes as people without depression and they are less likely to successfully quit than smokers without depression.

20 Sep 2013

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Results of a Pfizer-commissioned study published this month in Annals of Internal Medicine reveal that smokers with a past or present diagnosis of major depressive disorder (MDD)* taking varenicline had a significantly higher likelihood of quitting smoking (after 12 weeks and at 52 weeks) than those who were given a placebo.

18 Sep 2013

Researchers identify three risk factors that predict smoking initiation among young adults

The risk of becoming a smoker among young adults who have never smoked is high: 14% will become smokers between the ages of 18 and 24, and three factors predict this behaviour.

18 Sep 2013

Smoking-cessation in HIV-positive individuals: an interview with Dr Ellen R. Gritz, University of Texas MD Anderson Cancer Center

In the general population, current smoking prevalence is 18%. Persons living with HIV/AIDS smoke at a rate 2 to 3 times higher, up to almost 70% in some studies.

16 Sep 2013

Trial to compare e-cigarettes with nicotine patches shows success in helping smokers to quit

First trial to compare e-cigarettes with nicotine patches shows comparable success in helping smokers to quit.

10 Sep 2013

Researchers find key mechanism behind Alzheimer's disease

Alzheimer's disease affects more than 26 million people worldwide. It is predicted to skyrocket as boomers age-nearly 106 million people are projected to have the disease by 2050.

7 Sep 2013

Negative symptom clue to smoking in schizophrenia patients

Patients with schizophrenia may have a preponderance to cigarette smoking because it reduces negative symptom severity, researchers report.

5 Sep 2013

Increased risk caused by smoking is completely reversed after smoking cessation

Dr Dohi said: "Smokers are twice as likely to have a heart attack as people who have never smoked. Quitting smoking is the most important thing people can do to reduce their risk of cardiovascular disease. But until now, studies have not examined whether the increased risk caused by smoking is completely reversed after smoking cessation."

4 Sep 2013

Mayo Clinic’s programs offer hope and treatment to tobacco-dependent patients

Mayo Clinic's Nicotine Dependence Center (NDC) in Rochester is celebrating its 25th anniversary this year. As one of the first centers in the country to focus exclusively on treatments for tobacco dependence when it opened in 1988, the NDC has been at the forefront of the battle of nicotine addiction nationally as well as globally, offering the latest education and training programs, advancing research aimed at tobacco dependence interventions and offering treatment approaches to tobacco users.

30 Aug 2013

Four simple steps increase chances of preoperative smoking cessation

A simple four-part program-including referral to a quit-smoking hotline and a free supply of nicotine patches-can increase the percentage of patients who quit smoking before undergoing surgery, reports a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

23 Aug 2013

Experts research on potential role of e-cigarettes in smoking cessation

With the third and largest of the U.S. tobacco companies planning an e-cigarette product launch this fall, this next frontier for "Big Tobacco" provides renewed presence in a declining marketplace. It's also a potential gateway to new smokers, particularly among teens and in emerging/foreign markets, according to behavioral scientists at The University of Texas MD Anderson Cancer Center.

17 Aug 2013

More research needed to understand potential role of e-cigarettes in smoking cessation, say experts

With the third and largest of the U.S. tobacco companies planning an e-cigarette product launch this fall, this next frontier for “Big Tobacco” provides renewed presence in a declining marketplace. It’s also a potential gateway to new smokers, particularly among teens and in emerging/foreign markets, according to behavioral scientists at The University of Texas MD Anderson Cancer Center.

16 Aug 2013

Intervention delivered through mobile phones to HIV/AIDS-positive smokers increased cessation rates

A smoking-cessation intervention delivered through mobile phones to HIV/AIDS-positive smokers increased cessation rates compared to standard care, according to research published online in Clinical Infectious Diseases.

16 Aug 2013

Harmful toxins found in food may put developing babies at risk

Pregnant women regularly consume food and beverages containing toxins believed to pose potential risks to developing fetuses, according to researchers at the University of California in Riverside and San Diego, suggesting that health care providers must do more to counsel their patients about the dangers of hidden toxins in the food supply.

8 Aug 2013

Virginia Tech addiction expert receives $3.2 million grant to help smokers quit cigarettes

Warren Bickel, an internationally recognized addiction expert at the Virginia Tech Carilion Research Institute, recently received a $3.2-million grant from the National Institute on Drug Abuse for research on improving self-control in smokers seeking to quit cigarettes. The grant will provide Bickel's team with $573,000 to $716,000 a year over five years to develop innovative new ways to enhance the smokers' ability to abstain from acting on their nicotine cravings.

6 Aug 2013

Women who feel less attached to their fetus are going to smoke more

A small new study suggests that pregnant smokers with low scores on a scale that rates emotional attachment to their fetuses may be inclined to smoke more than pregnant smokers who feel more attached to their future babies.

6 Aug 2013

Great-grandmother's cigarette habit could be cause of child's asthma

With some 300 million people around the world living with asthma, a study by Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) researchers that was released ahead-of- print found for the first time that maternal smoking can cause the third generation of offspring to suffer from the chronic lung disease.

6 Aug 2013

Nicotine News and Research

Further Reading

ERK pathway discovery may provide therapeutic options for treating drug addictions

Time to first cigarette independently predicts lung cancer

Mother who smoke during her pregnancy may transmit asthma to future generation

Depressed smokers may benefit from mood management interventions

Smokers with a history of major depressive disorder (MDD) taking varenicline have significantly higher likelihood of quitting smoking than placebo

Researchers identify three risk factors that predict smoking initiation among young adults

Smoking-cessation in HIV-positive individuals: an interview with Dr Ellen R. Gritz, University of Texas MD Anderson Cancer Center

Trial to compare e-cigarettes with nicotine patches shows success in helping smokers to quit

Researchers find key mechanism behind Alzheimer's disease

Negative symptom clue to smoking in schizophrenia patients

Increased risk caused by smoking is completely reversed after smoking cessation

Mayo Clinic’s programs offer hope and treatment to tobacco-dependent patients

Four simple steps increase chances of preoperative smoking cessation

Experts research on potential role of e-cigarettes in smoking cessation

More research needed to understand potential role of e-cigarettes in smoking cessation, say experts

Intervention delivered through mobile phones to HIV/AIDS-positive smokers increased cessation rates

Harmful toxins found in food may put developing babies at risk

Virginia Tech addiction expert receives $3.2 million grant to help smokers quit cigarettes

Women who feel less attached to their fetus are going to smoke more

Great-grandmother's cigarette habit could be cause of child's asthma

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