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Measuring bone marrow fat can better predict weakening of bones

BMD measurement with DEXA is presently the most commonly used parameter for determining bone weakening. Researchers have long questioned whether there may be other measurable bone components that influence mechanical stability of bone.

7 Dec 2004

Human parathyroid gland most likely evolved from the gills of fish

The human parathyroid gland, which regulates the level of calcium in the blood, probably evolved from the gills of fish, according to researchers from King's College London.

6 Dec 2004

Thalidomide shows promise in fighting myeloma

Thalidomide, a drug often used to treat symptoms of leprosy and in testing to fight HIV, is now demonstrating activity in fighting a common cancer that occurs in bone marrow, myeloma.

6 Dec 2004

New advances in sickle cell disease

Excruciating pain episodes, recurrent pneumonias, strokes, severe infections, chronic hemolytic anemia, and secondary pulmonary hypertension are common complications of sickle cell disease, a life-threatening inherited defect in blood that causes normally disc-shaped red blood cells to take on a sickle shape.

6 Dec 2004

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Modern research is delving deep into the human genome to find the answers to medical mysteries and, hopefully, cures for the most deadly diseases. According to four new studies presented during the 46th Annual Meeting of the American Society of Hematology

5 Dec 2004

Researchers step closer to cure for common childhood cancer

Acute lymphoblastic leukemia (ALL) is a malignant disease caused by the abnormal growth and development of white blood cells (WBC) in the bone marrow and blood. ALL is the most common cancer occurring in children with an annual rate of approximately 30 to 40 new cases per million.

5 Dec 2004

Hydroxyurea plus aspirin best therapy in patients with essential thrombocythemia who are at high risk for vascular events

A new treatment for an incurable blood disorder proves a worse option for patients' health than an older treatment, according to a study to be presented today during the 46th Annual Meeting of the American Society of Hematology (ASH).

5 Dec 2004

Genetic target found for pediatric leukemia

A molecular target newly discovered by scientists at two prestigious research institutes may pave the way for new treatments that could combat an aggressive form of leukemia, according to a study to be presented today during the 46th Annual Meeting of the American Society of Hematology (ASH).

5 Dec 2004

Positive results from phase 2 trial of Telintra, drug candidate in myelodysplastic syndrome

Telik, Inc. reported positive interim data from a Phase 2 trial of its Telintra (TLK199) drug candidate in myelodysplastic syndrome (MDS). The data were reported in two presentations at the annual meeting of the American Society of Hematology in San Diego.

5 Dec 2004

Data from phase II study of Trisenox (arsenic trioxide) injection in myelodysplasia

At the 46th Annual Meeting of the American Society of Hematology (ASH) preliminary data were presented from a phase II study of Trisenox (arsenic trioxide) injection in myelodysplasia (MDS).

5 Dec 2004

Single dose phase I data on CG53135 for the prevention of oral mucositis

CuraGen Corporation has announced results presented from a Phase I clinical trial with CG53135 for the prevention of oral mucositis (OM) in patients receiving high dose chemotherapy (HDCT) followed by autologous hematopoietic stem cell transplantation (AHSCT) at the ASH 46th Annual Meeting in San Diego, CA.

5 Dec 2004

Low level exposure to Benzene causes lower blood cell counts

A new study found that white blood cell counts were lowered in workers exposed to less than 1 ppm of the chemical benzene (part benzene per million parts air).

3 Dec 2004

Method for healing spinal injuries in dogs offers hope for preventing human paralysis

Lab tests have shown that an injection of a liquid polymer known as polyethylene glycol (PEG), if administered within 72 hours of serious spinal injury, can prevent most dogs from suffering permanent spinal damage.

3 Dec 2004

Guidelines needed for the use of androgens for women with sexual dysfunction

The Endocrine Society, which represents more than 12,000 endocrinologists who are specially trained to diagnose, treat and conduct basic and clinical research on complex hormonal disorders, has called for new clinical guidelines on the use of androgens in women/female sexual dysfunction.

3 Dec 2004

Tofu-based biomaterial that can help mend broken bones

A new Tofu-based biomaterial that can help mend broken bones and damaged tissues is being developed thanks to an investment of £149,000 from NESTA (the National Endowment for Science, Technology and the Arts), the organization that champions UK creativity and innovation.

2 Dec 2004

Thyroid treatments can set off radiation detectors

Medical procedures such as iodine therapy, a popular thyroid treatment, can result in patients triggering radiation detectors for up to three months after treatment, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

30 Nov 2004

Imatinib mesylate (Gleevec) inhibits important pathways that spur cancer growth

A new clinical study has shown that imatinib mesylate (Gleevec) has activity in AIDS-related Kaposi's sarcoma (KS). Imatinib inhibits important pathways that spur cancer growth, resulting in the regression of KS tumors within 4 weeks in some patients. The study will be published November 30 in the Journal of Clinical Oncology (JCO).

30 Nov 2004

Low testosterone production appears to be a common complication of type 2 diabetes in men

Moreover, results of the investigation show that this condition, known clinically as hypogonadism, is caused not by a defect in the testes, where testosterone is produced, but by improper functioning of the pituitary gland, which controls production of testosterone, or of the hypothalamus, the region of the brain that controls the pituitary.

29 Nov 2004

Study finds that stomach cancer originates from bone marrow derived stem cells, rather than from stomach stem cells

A common assumption among cancer specialists is that most cancers originate from tissue stem cells – for example, the gastric stem cells contained in the lining of the stomach.

29 Nov 2004

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

A new study published in the New England Journal of Medicine confirms that stem cells derived from the umbilical cords of newborn babies are a viable and effective transplant source for thousands of leukemia patients who have no other treatment option.

24 Nov 2004

Bone News and Research

Measuring bone marrow fat can better predict weakening of bones

Human parathyroid gland most likely evolved from the gills of fish

Thalidomide shows promise in fighting myeloma

New advances in sickle cell disease

Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Researchers step closer to cure for common childhood cancer

Hydroxyurea plus aspirin best therapy in patients with essential thrombocythemia who are at high risk for vascular events

Genetic target found for pediatric leukemia

Positive results from phase 2 trial of Telintra, drug candidate in myelodysplastic syndrome

Data from phase II study of Trisenox (arsenic trioxide) injection in myelodysplasia

Single dose phase I data on CG53135 for the prevention of oral mucositis

Low level exposure to Benzene causes lower blood cell counts

Method for healing spinal injuries in dogs offers hope for preventing human paralysis

Guidelines needed for the use of androgens for women with sexual dysfunction

Tofu-based biomaterial that can help mend broken bones

Thyroid treatments can set off radiation detectors

Imatinib mesylate (Gleevec) inhibits important pathways that spur cancer growth

Low testosterone production appears to be a common complication of type 2 diabetes in men

Study finds that stomach cancer originates from bone marrow derived stem cells, rather than from stomach stem cells

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

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