Hepatology News and Research

RSS

Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

Study compares outcome of popular esophageal stents in patients with dysphagia

Less than 50% of patients with esophageal carcinoma are suitable for surgery at the time of diagnosis. Most of these patients present with locally advanced or metastatic disease and/or significant comorbidities. In such circumstances, the only therapeutic option is palliative care to treat dysphagia and prevent respiratory complications secondary to aspiration. Self-expanding metal stents have been proven effective for palliation of dysphagia in patients with esophageal carcinoma, tracheo-esophageal fistulas or anastomotic leaks.

13 May 2010

Report describes imaging features of superior mesenteric artery aneurysm

A recent case report published on May 14, 2010 in World Journal of Gastroenterology describes the imaging features of a ruptured superior mesenteric artery aneurysm,which created a giant hematoma and mimicked a pancreatic mass, with mild dilatation of main pancreatic duct.

13 May 2010

New case report addresses diagnostic significance of CT and MRI for DCF

Duodenocaval fistula is an uncommon but lethal clinical entity. The high mortality has been attributed to the difficulty of diagnosis before attempts at definitive therapy.

13 May 2010

Study evaluates cost-utility of MARS treatment in ALF patients

Numerous studies have documented the favorable effects of MARS albumin dialysis treatment on clinical and laboratory parameters and survival in liver failure patients. However, to ensure that limited resources are utilized in an ethical manner, the subjective feelings of the patient in terms of health-related quality of life and costs should also be taken into account.

13 May 2010

Risk of venous thromboembolism is low after hepatic resection in cirrhotic patients: Researchers

Hepatocellular carcinoma is the most common primary neoplasm of the liver and often arises in the context of a chronic liver disease that impairs coagulative function. Surgical resection is the best option to cure HCC, however, surgery on cirrhotic liver may increase the risk of bleeding.

12 May 2010

Sucampo presents phase 3 trial results of lubiprostone in non-cancer pain patients with OBD at DDW 2010

Sucampo Pharmaceuticals, Inc. today announced the presentation of results from a phase 3 clinical trial investigating the use of lubiprostone in non-cancer pain patients with Opioid-induced Bowel Dysfunction (OBD). These results were the subject of an oral presentation at the Digestive Disease Week (DDW) 2010 conference in New Orleans, Louisiana, on May 5, 2010.

11 May 2010

CE 3D US creates spatial view for hemodynamic and morphologic evaluation of focal liver tumors

Recently, contrast-enhanced (CE) ultrasound (US) appeared as an important modality to show the vascularity in the areas of interest, and has been used widely in clinical diagnosis of liver lesions. Three dimensional ultrasonography (3D US) allows three orthogonal planes to spatially demonstrate the features of subjects, which has been frequently used in fetal US.

10 May 2010

Double-balloon endoscopy reveals intestinal lipomas within jejunal duplication cysts

Lipoma of the small intestine is a benign tumor of mesenchymal origin which is mostly found by chance during gastrointestinal investigation. Invaginations account for 2/3 of small bowel occlusion caused by up to 80% of tumors and the lipoma is the most frequent benign tumor that causes invagination in its submucous polypoid and it is in more or less scissile form.

10 May 2010

H. pylori eradication therapy treatment for localized H. pylori-negative gastric MALT lymphoma

Eradication of Helicobacter pylori is a well-accepted initial therapy in cases of localized (stage ⅠE) low-grade gastric mucosa-associated lymphoid tissue lymphoma associated with H. pylori infection. However, there are no treatment guidelines for the management of H. pylori-negative low-grade gastric MALT lymphoma.

7 May 2010

Report: 34 C>G of PPAR-γ gene might be a potential therapeutic target for colon cancer

Colorectal cancer is one of the major causes of cancer death in the developed countries. Accumulated evidences indicate that lipid metabolism, especially the one in the arachidonic acid -pathway, appears to play a critical role in the development of CRC.

7 May 2010

Researchers investigate aberrant expression of nuclear matrix proteins in gastric cancer cells

Gastric cancer is the most common malignant gastrointestinal cancer and accounts for 25% of cancer deaths. Nuclear matrix, a filamentous protein framework for eukaryotic cellular chromatin, closely relates to DNA duplication and transcription. Research on nuclear matrix proteins will provide insight into how tumors developed.

7 May 2010

Minimally invasive scopes to detect cancer

Just as cameras and televisions have been reinvented in the last decade with improved optics, sharpness and brightness, so have the tiny imaging scopes that physicians use to peer into the body's nooks and crannies -- its organs and digestive system.

7 May 2010

Hepcidin is found in various biological fluids, says new research

Recent studies have highlighted the importance of hepcidin in iron metabolism, particularly anaemia of chronic disease and iron overload. There have also been reports of its expression in various proinflammatory disorders and various organs, linking it to innate immunity and iron metabolism.

7 May 2010

Colonoscopy preparation drugs administered same day as procedure equally effective: Researchers

Researchers at Thomas Jefferson University have found that colonoscopy preparation drugs administered the same day as the procedure are equally effective to those given the night before and the morning of the procedure, but result in less complaints of side effects such as abdominal pain, sleep loss and workday interference.

6 May 2010

Pay-for-performance may create unintended financial incentives for doctors to discriminate against obese patients

Pay-for-performance reimbursement models may create unintended financial incentives for doctors to discriminate against obese patients, measuring a patient's waist circumference may be more effective in predicting surgical outcomes than the more traditional body mass index measure, and childhood obesity doubles the risk of developing colon cancer, according to data being presented at Digestive Disease Week- 2010.

5 May 2010

Colorectal pre-cancer can be detected through stool DNA testing: Mayo Clinic study

Research teams led by Mayo Clinic have demonstrated for the first time that two types of colorectal pre-cancers can be detected through noninvasive stool DNA testing. The two studies being presented demonstrate that stool DNA testing may be useful for detection of premalignant dysplasia in patients with inflammatory bowel disease and of an important type of colorectal pre-cancer called serrated polyps.

5 May 2010

New pathology test may help doctors distinguish between two overlapping esophageal disorders: Study

A pathology test may help doctors distinguish between two separate but overlapping esophageal disorders that require different courses of treatment, according to a study by researchers at the University of North Carolina at Chapel Hill.

5 May 2010

Data shows rates of colorectal cancer screening vary by race, ethnicity and method

Rates of colorectal cancer screening vary by race and ethnicity as well as method, according to data being presented at Digestive Disease Week- 2010. Scientists examine data on minority and older populations as well as utilization rates of virtual and optical colonoscopies to better understand adherence to recommended screening guidelines.

5 May 2010

Results from STEALTH C-3 clinical trial of nitazoxanide presented at DDW 2010

Romark Laboratories announced results from its STEALTH C-3 clinical trial, a phase 2 clinical study of nitazoxanide in treatment-naive patients with genotype 1 chronic hepatitis C. Study results were presented this afternoon as an oral communication at a late breaking forum of the American Gastroenterological Association Institute during Digestive Disease Week 2010 in New Orleans, Louisiana.

5 May 2010

Idera Pharmaceuticals reports net loss of $1.9M for first-quarter 2010

Idera Pharmaceuticals, Inc., a biotechnology company engaged in the discovery and development of DNA- and RNA-based drug candidates targeted to Toll-like Receptors, today reported financial results for the first quarter ended March 31, 2010.

5 May 2010

Hepatology News and Research

Further Reading

Study compares outcome of popular esophageal stents in patients with dysphagia

Report describes imaging features of superior mesenteric artery aneurysm

New case report addresses diagnostic significance of CT and MRI for DCF

Study evaluates cost-utility of MARS treatment in ALF patients

Risk of venous thromboembolism is low after hepatic resection in cirrhotic patients: Researchers

Sucampo presents phase 3 trial results of lubiprostone in non-cancer pain patients with OBD at DDW 2010

CE 3D US creates spatial view for hemodynamic and morphologic evaluation of focal liver tumors

Double-balloon endoscopy reveals intestinal lipomas within jejunal duplication cysts

H. pylori eradication therapy treatment for localized H. pylori-negative gastric MALT lymphoma

Report: 34 C>G of PPAR-γ gene might be a potential therapeutic target for colon cancer

Researchers investigate aberrant expression of nuclear matrix proteins in gastric cancer cells

Minimally invasive scopes to detect cancer

Hepcidin is found in various biological fluids, says new research

Colonoscopy preparation drugs administered same day as procedure equally effective: Researchers

Pay-for-performance may create unintended financial incentives for doctors to discriminate against obese patients

Colorectal pre-cancer can be detected through stool DNA testing: Mayo Clinic study

New pathology test may help doctors distinguish between two overlapping esophageal disorders: Study

Data shows rates of colorectal cancer screening vary by race, ethnicity and method

Results from STEALTH C-3 clinical trial of nitazoxanide presented at DDW 2010

Idera Pharmaceuticals reports net loss of $1.9M for first-quarter 2010

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

Latest News