Organelle News and Research

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McGill researchers discover bacterial organelles involved in gene expression

Researchers at McGill University have discovered bacterial organelles involved in gene expression, suggesting that bacteria may not be as simple as once thought.

20 Jul 2020

Novel mechanism regulates planar cell polarity crucial for organ function

Planar cell polarity (PCP), a process in which the epithelial tissues are polarized within the plane of the epithelium, plays an important role in development and organ function.

8 Jul 2020

SARS-CoV-2 infection modeling in iPSC-derived type 2 cells

The most fatal form of COVID-19 disease is acute respiratory distress syndrome (ARDS), caused by direct viral injury as well as indirect noxious effects caused by cytotoxic chemicals and inflammatory processes. A new study published on the preprint server bioRxiv* in June 2020 shows that this is partly due to the rapid onset of inflammation caused by the infection of type 2 alveolar cells with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Jul 2020

UCD spin-out awarded €4.5 million funding to help combat coronavirus pandemic

SiriusXT (https://siriusxt.com/), a University College Dublin (UCD) spin-out company, has been awarded just over €4.5 million in blended (grant and equity) funding from the European Innovation Council Accelerator Pilot programme which is part of Horizon 2020, the EU's research and innovation programme.

11 Jun 2020

Study provides new evidence that liver dysfunction may lead to heart disease

A new study that looks closely at the cardiac health of flies provides new evidence that liver dysfunction may lead to deterioration of the heart.

10 Jun 2020

Study reveals new strategy to tackle cancer

A study led by the Institut de Neurociències describes a new strategy to tackle cancer, based on inducing a potent stress in tumor causing cell destruction by autophagy.

9 Jun 2020

Virginia Tech researcher develops new ‘fat burning’ molecule with potential to treat obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

8 Jun 2020

Improving IVF Treatments by Imaging Sperm Cells

News-Medical spoke to Professor Natan Shaked about his new sperm cell imaging technique that could be used to help improve the outcomes of IVF treatments.

22 May 2020

Scientists discover new metabolism regulation system for the brown adipose tissue

Scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes.

8 May 2020

Phase separation enables organelles to respond to changing cellular conditions

New findings about critical cellular structures have upended common assumptions about their formation and composition and provided new insight how molecular machines are built in living cells.

7 May 2020

Study provides evidence for safety and efficacy of chloroquine in COVID-19

After a pilot study (Huang et al.Journal of Molecular Cell Biology, in press), having proved the safety and effectiveness of the drug to reduce the viral RNA to undetectable levels in 10 COVID-19 patients, the researchers began this current study, published on the preprint server medRxiv.

5 May 2020

Study describes unconventional mechanism of ionic channel traffic in cardiac cells

Ionic channels -integral proteins in the cell membrane- are essential in several processes such as cardiac activity, nervous transmission, cell proliferation and the regulation of blood pressure.

18 Apr 2020

Study sheds light on how a group of novel organelle-based disorders affects cells

A pioneering study has shed new light on how a group of novel organelle-based disorders affect cells.

10 Apr 2020

Study reveals new mechanism underlying organelle communication in brown fat cells

In recent years, brown fat has garnered increasing attention as the so-called good fat that can protect against obesity and associated health risks, like cardiovascular disease and diabetes.

30 Mar 2020

How do cells protect themselves from viruses?

Amid the coronavirus outbreak that is wreaking havoc across the globe, it is essential to know how the cells of the body evade infection from viruses. A team of scientists has explained the mechanism that takes place in case a virus penetrates the body.

4 Mar 2020

Clemson researchers discover protein function in parasites which afflict millions with diseases

In the quest to develop more effective treatments for parasitic diseases like African sleeping sickness, Chagas disease and Leishmaniasis, scientists look for weaknesses in the organisms' molecular machinery. These weaknesses can then be targeted with drug therapies designed to kill the parasites.

24 Feb 2020

Newly discovered large phages blur the life/non-life boundary

A new study published in the journal Nature shows that there are literally hundreds of viruses large enough to consume bacteria, and with properties that are typical of a living organism rather than the non-living self-replicating packages of DNA/RNA that viruses are often assumed to be.

12 Feb 2020

Study reveals presence of functional extracellular mitochondria in the bloodstream

Mitochondria are organelles that are found in the eukaryotic cells. A place of cellular respiration, they are the cells' "batteries" and play a major role in energy metabolism and intercellular communication.

23 Jan 2020

Biophysicists shed light on the structure, functioning mechanism of CysLT receptors

Biophysicists from the MIPT Center for Molecular Mechanisms of Aging and Age-Related Diseases have teamed up with colleagues from Canada, the U.S., Japan, France, and Germany to shed light on the structure and functioning mechanism of the CysLT receptors, which regulate inflammatory responses associated with allergic disorders.

21 Jan 2020

Enzymes that cannibalize each other and promote cancer

A new study to be published this week in the journal The Proceedings of the National Academy of Sciences in the week of January 20, 2020. shows that certain human enzymes play dual roles in health and disease. Not only do they promote the occurrence of cancer and some other illnesses, they also eliminate one another rather like cannibals. The researchers hope this behaviour can be exploited to prevent these enzymes from causing human disease.

20 Jan 2020