Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Actor-patients' requests for medications boost prescribing for depression

Researchers funded by the National Institute of Mental Health (NIMH), have found that requests from patients for medications have a "profound effect" on physicians prescribing for major depression and adjustment disorder. These findings indicate that direct-to-consumer (DTC) marketing of prescription medications for depression may exert significant influence on treatment decisions.

27 Apr 2005

The power of advertising means you may get medications you don't need

A study published this month confirms what has often been suspected, that prescription drug advertising not only persuades patients to ask for certain medications but also has a profound influence on what doctors prescribe.

26 Apr 2005

Direct-to-consumer advertising may influence physicians' prescribing decisions

Patients requesting specific medications can have a profound effect on physicians prescribing medications for major depression, according to a new study in the April 27 issue of JAMA.

26 Apr 2005

Study may lead to a better understanding of how antidepressants like Prozac work

According to results published in today's issue of the journal Neuron, a study in mice proposes that dopamine and serotonin neurotransmitter systems in the brain occasionally get their signals crossed, causing delays in stabilizing mood.

7 Apr 2005

SSRI antidepressants "hijack" dopamine signaling as well launching serotonin signals

Researchers have discovered that antidepressant drugs such as Prozac not only affect levels of the neurotransmitter serotonin in the brain, but also "hijack" dopamine signaling as well--causing it to launch serotonin signals. Their findings offer new insight into how Prozac and other "selective serotonin uptake inhibitors" (SSRIs) work and how they might cause problems in patients taking them.

6 Apr 2005

Cognitive therapy to treat moderate to severe depression works just as well as antidepressants

The study, conducted by researchers at the University of Pennsylvania and Vanderbilt University, challenges the American Psychiatric Association guidelines that antidepressant medications are the only effective treatment for moderately to severely depressed patients.

5 Apr 2005

Light therapy effectively treats mood disorders

A study commissioned by the American Psychiatric Association and led by a psychiatrist at the University of North Carolina at Chapel Hill School of Medicine has found that light therapy effectively treats mood disorders, including seasonal affective disorder (SAD) and other depressive disorders.

4 Apr 2005

Cognitive therapy may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression

Cognitive therapy, when provided by an experienced therapist, may be as effective as antidepressant medications in the initial treatment of moderate to severe major depression, according to an article in the April issue of Archives of General Psychiatry.

4 Apr 2005

Finding opens new doors to determining susceptibility to antidepressant side effects

In a finding that opens new doors to determining susceptibility to antidepressant side effects, researchers at the UCLA Neuropsychiatric Institute report that changes in brain activity prior to treatment with antidepressants can flag patient vulnerability.

30 Mar 2005

Does depression predict mortality in heart attacks?

A group of Danish investigators, headed by Per Bech (Hillerod) surveyed the the literature on depression in patients with myocardial infarction to assess the methodological quality and to test whether depression leads to an increased postmyocardial infarction mortality.

21 Mar 2005

Costs of antidepressants could have funded effective alternatives

Some of the costs of prescribing antidepressant drugs over the last decade could have been used to deliver psychological treatments of proven effectiveness, finds a study published online by the BMJ.

21 Mar 2005

Antidepressants not the culprit in depression linked to heart attacks

The increased risk of heart attack associated with taking antidepressants may be caused by the depression itself rather than the drugs themselves, suggests new research reported in the current issue in the British Medical Journal. At least one in 10 older people are prescribed antidepressants.

15 Mar 2005

U.S Marshals action affects Glaxo share price

Early this month, U.S. marshals seized batches of Paxil CR and Avandamet at manufacturing and distribution sites in Puerto Rico and Knoxville, Tennessee.

8 Mar 2005

St. John's wort increases effectiveness of Plavix

The widely used herbal remedy St. John's wort appears to amplify the action of the popular blood-thinning drug clopidogrel, sold as Plavix, a small new clinical study finds.

6 Mar 2005

New method of organising care for adults in the UK who suffer from clinical depression

Researchers at the University of York are investigating a new method of organising care for some of the three million adults in the UK who suffer from clinical depression.

6 Mar 2005

Batches of the drugs Paxil and Avandamet seized by federal officials

Batches of the drugs Paxil CR and Avandamet United States, were seized by marshals at manufacturing and distribution plants in Tennessee and Puerto Rico after federal officials said the manufacturer failed to correct violations of production safety standards.

5 Mar 2005

Deep brain stimulation alleviates severe depression

Canadian researchers have found that severe depression, which is often unresponsive to standard treatments, may be alleviated with an experimental treatment called deep brain stimulation.

3 Mar 2005

Antidepressants prescribed to children will have Black Box labels warnings

Antidepressants prescribed to children should have "Black box" labels warnings, which are reserved for the most dangerous drugs, of the increased risk of suicide that they pose. This will happen mid-March, five months after the Food and Drug Administration ordered it.

3 Mar 2005

Unique study of the use of deep brain stimulation

Canadian researchers have seen promising results from a unique study of the use of deep brain stimulation (DBS), in severely depressed patients resistant to standard treatments.

28 Feb 2005

Electrical deep brain stimulation can dramatically alleviate depression

Electrical deep brain stimulation can dramatically alleviate depression that is resistant to other treatments, researchers have found in an initial study on six patients.

28 Feb 2005