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Ohio State University researchers awarded NCI grant to further study thyroid cancer

The National Cancer Institute has awarded a five-year, $11.3 million grant to a team of researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute to further their studies on thyroid cancer.

5 Sep 2013

Sirt1 Protein, Not Calorie Restriction, Extends Life Span

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4 Sep 2013

Boosting Your Brain Power With Sleep

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4 Sep 2013

New mechanism operates specific protein in brain to bring delay in aging

Among scientists, the role of proteins called sirtuins in enhancing longevity has been hotly debated, driven by contradictory results from many different scientists. But new research at Washington University School of Medicine in St. Louis may settle the dispute.

4 Sep 2013

Research on long-lived proteins may lead to better understanding of molecular basis of aging

Proteins are the chief actors in cells, carrying out the duties specified by information encoded in our genes. Most proteins live only two days or less, ensuring that those damaged by inevitable chemical modifications are replaced with new functional copies.

4 Sep 2013

New method to detect genetic variations that initiate colon cancer

A new, highly sensitive method to detect genetic variations that initiate colon cancer could be readily used for noninvasive colon cancer screening, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

4 Sep 2013

Research: Females can maximise genetic quality of their offspring by being promiscuous

New research from the University of East Anglia has shown that females can maximise the genetic quality of their offspring by being promiscuous.

4 Sep 2013

Researchers identify role played by protein in controlling brain activity during seizure

People with epilepsy could be helped by new research into the way a key molecule controls brain activity during a seizure. Researchers have identified the role played by of a protein - called BDNF - and say the discovery could lead to new drugs that calm the symptoms of epileptic seizures.

4 Sep 2013

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Like naked mole-rats (Heterocephalus gaber), blind mole-rats (of the genus Spalax) live underground in low-oxygen environments, are long-lived and resistant to cancer. A new study demonstrates just how cancer-resistant Spalax are, and suggests that the adaptations that help these rodents survive in low-oxygen environments also play a role in their longevity and cancer resistance.

4 Sep 2013

Study: Changes in expression of various isoforms might play role in cancer development

Spool-like proteins called histones play a crucial role in packaging the nearly seven feet of DNA found in most human cells. A new study shows that a group of histones that are thought to behave the same way actually are functionally distinct proteins.

4 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Research: Male sexual development less stable than other genetic programs

The idea that men and women are fundamentally different from each other is widely accepted. And throughout the world, this has created distinct ideas about which social and physical characteristics are necessary in each gender to maintain healthy human development.

3 Sep 2013

New quick test promises to reduce economic, health burden of syphilis cases in Latin America

Demystifying the chemical processes that create a wine's aroma, and the invaluable potential application of that understanding in winemaking, is the new objective of scientists in Uruguay who, with European partners, also recently sequenced the genome of the high-value Tannat grape, from which "the most healthy of red wines" are fermented.

2 Sep 2013

ddPCR technology can be used to reproducibly quantify microRNA in plasma

A study published online in Nature Methods today demonstrated that Droplet Digital PCR (ddPCR-) technology can be used to precisely and reproducibly quantify microRNA (miRNA) in plasma and serum across different days, paving the way for further development of miRNA and other nucleic acids as circulating biomarkers.

2 Sep 2013

Debiopharm starts Debio 1347 phase I study in patients with advanced solid tumors

Debiopharm Group, the Swiss-based global biopharmaceutical company that focuses on the development of prescription drugs that target unmet medical needs including oncology, today announced the start of a phase I, open label multicenter study of a selective FGFR 1, 2, 3 inhibitor, Debio 1347 (CH5183284) in patients with advanced solid tumors.

2 Sep 2013

Holistic approach to understand and treat TB

For years, physicians around the world have watched as strain after strain of the deadly bacteria Mycobacterium tuberculosis evolves resistance to drugs.

2 Sep 2013

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Nanoscale "cages" made from strands of DNA can encapsulate small-molecule drugs and release them in response to a specific stimulus, McGill University researchers report in a new study.

2 Sep 2013

Researchers discover role played by epigenetic factors in senescence and age-related diseases

One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication.

31 Aug 2013

Researchers identify potential drug target to recover from jet lag, disruptions in circadian system

University of Notre Dame researchers, as part of a collaborative effort, have identified a protein that potentially could be a target for drugs that would help people recover faster from jet lag and better adjust their circadian rhythms during rotational shift work.

31 Aug 2013

Study: Mosquitoes able to smell major human host odorants better at night

In work published this week in Nature: Scientific Reports, a team of researchers from the University of Notre Dame's Eck Institute for Global Health, led by Associate Professor Giles Duffield and Assistant Professor Zain Syed of the Department of Biological Sciences, revealed that the major malaria vector in Africa, the Anopheles gambiae mosquito, is able to smell major human host odorants better at night.

31 Aug 2013

Genes News and Research

Ohio State University researchers awarded NCI grant to further study thyroid cancer

Sirt1 Protein, Not Calorie Restriction, Extends Life Span

Boosting Your Brain Power With Sleep

New mechanism operates specific protein in brain to bring delay in aging

Research on long-lived proteins may lead to better understanding of molecular basis of aging

New method to detect genetic variations that initiate colon cancer

Research: Females can maximise genetic quality of their offspring by being promiscuous

Researchers identify role played by protein in controlling brain activity during seizure

Blind mole-rats live underground in low-oxygen environments, are long-lived and resistant to cancer

Study: Changes in expression of various isoforms might play role in cancer development

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Research: Male sexual development less stable than other genetic programs

New quick test promises to reduce economic, health burden of syphilis cases in Latin America

ddPCR technology can be used to reproducibly quantify microRNA in plasma

Debiopharm starts Debio 1347 phase I study in patients with advanced solid tumors

Holistic approach to understand and treat TB

Nanostructures made of DNA strands can encapsulate, release small-molecule drugs

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Researchers identify potential drug target to recover from jet lag, disruptions in circadian system

Study: Mosquitoes able to smell major human host odorants better at night

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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