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UAB study points to protein pathway that could lead to new treatments for diabetes

The same protein tells beta cells in the pancreas to stop making insulin and then to self-destruct as diabetes worsens, according to a University of Alabama at Birmingham study published online today in the journal Nature Medicine.

27 Aug 2013

New bioinformatics software tool to identify genetic mutations responsible for cancers

Researchers at the Medical College of Wisconsin (MCW) have developed a new bioinformatics software tool designed to more easily identify genetic mutations responsible for cancers. The tool, called DrGaP, is the subject of a new paper published in the American Journal of Human Genetics.

27 Aug 2013

Study: Structural defect in skin cells can contribute to allergy development

In a new study published in Nature Genetics, Northwestern Medicine and Tel Aviv University scientists have found that a structural defect in skin cells can contribute to allergy development, including skin and food allergies, traditionally thought primarily to be a dysfunction of the immune system.

27 Aug 2013

Two Genomic Pathways Tagged For Roles In Schizophrenia

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26 Aug 2013

Compatibility gene may influence finding life partner as well as our health, individuality

A University of Manchester professor and his wife have had their own DNA analysed for compatibility as part of the research for a new book out on 1 October in the US and next week in the UK.

From The University of Manchester 26 Aug 2013

Scientists identify specific type of receptor that may aid in treatment of AD, Parkinson’s disease

Scientists at Washington University School of Medicine in St. Louis have found a way that corrupted, disease-causing proteins spread in the brain, potentially contributing to Alzheimer's disease, Parkinson's disease and other brain-damaging disorders.

26 Aug 2013

Study identifies 22 locations in the human genome that cause schizophrenia

A new genome-wide association study estimates the number of different places in the human genome that are involved in schizophrenia.

26 Aug 2013

Scientists discover crucial role of nitric oxide in cellular signaling and health

Scientists at the University of Illinois at Chicago College of Pharmacy have discovered a new role for nitric oxide, a gas molecule crucial for cellular signaling and health.

26 Aug 2013

Study compares spectrum of cancer-related gene mutations in two common types of cervical cancer

A new study has revealed marked differences in the genomic terrain of the two most common types of cervical cancer, suggesting that patients might benefit from therapies geared to each type's molecular idiosyncrasies.

26 Aug 2013

Model including dozens of mutations helps clarify genetic factors involved in Crohn's disease

A statistical model accounting for dozens of different genes in combination-and the interactions between them-is an important step forward in understanding the genetic factors affecting the risk of Crohn's disease (CD), reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

26 Aug 2013

Glutathione peroxidase activity protects against symptoms of Huntington's disease

Leicester geneticists have discovered a potential defence against Huntington's disease - a fatal neurodegenerative disorder which currently has no cure.

26 Aug 2013

Researchers identify compound that eases symptoms of Parkinson's disease

Researchers at Johns Hopkins and elsewhere have brought new clarity to the picture of what goes awry in the brain during Parkinson's disease and identified a compound that eases the disease's symptoms in mice.

26 Aug 2013

Scientists Shed New Light On Malignant Pancreatic Cancer

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23 Aug 2013

Scientists discover that chromosomal rearrangements can be advantageous

In a pioneer study published in the latest issue of the scientific journal Nature Communications, a research team at the Instituto Gulbenkian de Ci-ncia (IGC; Portugal), led by Miguel Godinho Ferreira in collaboration with Isabel Gordo, show for the first time that chromosomes rearrangements (such as inversions or translocations) can provide advantages to the cells that harbor them depending on the environment they are exposed.

23 Aug 2013

Research findings lay foundation for regenerating damaged heart muscle

In the aftermath of a heart attack, cells within the region most affected shut down. They stop beating. And they become entombed in scar tissue. But now, scientists at the Gladstone Institutes have demonstrated that this damage need not be permanent-by finding a way to transform the class of cells that form human scar tissue into those that closely resemble beating heart cells.

23 Aug 2013

New technique may convert cells from heart disease patients into heart muscle cells

Researchers have developed a new technique that might one day be used to convert cells from heart disease patients into heart muscle cells that could act as a personalized treatment for their condition.

23 Aug 2013

Understanding genetic factors that affect Crohn's disease risk

A statistical model accounting for dozens of different genes in combination—and the interactions between them—is an important step forward in understanding the genetic factors affecting the risk of Crohn's disease, reports a study in Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America.

23 Aug 2013

ATF3 gene may be the crucial link between stress and breast cancer: Study

In an unexpected finding, scientists have linked the activation of a stress gene in immune-system cells to the spread of breast cancer to other parts of the body.

23 Aug 2013

Drug to treat blood cancers may also stop spread of invasive breast cancer

A drug used to treat blood cancers may also stop the spread of invasive breast cancer, researchers at Mayo Clinic in Florida have discovered. Their study, published online in Breast Cancer Research, found that in the lab and in animals, the drug decitabine turns on a gene coding for protein kinase D1 (PRKD1) that halts the ability of cancer cells to separate from a tumor and spread to distant organs.

23 Aug 2013

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

Variants in a particular gene are linked with an increased risk for kidney complications in patients with lupus, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology. The findings could lead to better treatments to protect the kidney health of patients with the disease.

23 Aug 2013

Genes News and Research

UAB study points to protein pathway that could lead to new treatments for diabetes

New bioinformatics software tool to identify genetic mutations responsible for cancers

Study: Structural defect in skin cells can contribute to allergy development

Two Genomic Pathways Tagged For Roles In Schizophrenia

Compatibility gene may influence finding life partner as well as our health, individuality

Scientists identify specific type of receptor that may aid in treatment of AD, Parkinson’s disease

Study identifies 22 locations in the human genome that cause schizophrenia

Scientists discover crucial role of nitric oxide in cellular signaling and health

Study compares spectrum of cancer-related gene mutations in two common types of cervical cancer

Model including dozens of mutations helps clarify genetic factors involved in Crohn's disease

Glutathione peroxidase activity protects against symptoms of Huntington's disease

Researchers identify compound that eases symptoms of Parkinson's disease

Scientists Shed New Light On Malignant Pancreatic Cancer

Scientists discover that chromosomal rearrangements can be advantageous

Research findings lay foundation for regenerating damaged heart muscle

New technique may convert cells from heart disease patients into heart muscle cells

Understanding genetic factors that affect Crohn's disease risk

ATF3 gene may be the crucial link between stress and breast cancer: Study

Drug to treat blood cancers may also stop spread of invasive breast cancer

Study: Gene variants linked with increased risk for kidney complications in patients with lupus

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