CLARITY News and Research

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The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.

Understanding how patients and families describe major medical treatments

When patients and their families face important decisions about major medical treatments, understanding how they describe them in their own words may help clinicians provide clarity and support through the decision-making process.

1 Nov 2022

Hospitals said they lost money on Medicare patients. Some made millions, a state report finds.

Atrium Health, the largest hospital system in North Carolina, has declared publicly that in 2019 it provided $640 million in services to Medicare patients that were never paid for, by far the largest "community benefit" it provided that year.

25 Oct 2022

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.

20 Oct 2022

Beckman Coulter Life Sciences presenting at ASHG

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, will have a full team of dedicated professionals and informative programming at the American Society of Human Genetics (ASHG) Annual Meeting October 25-29, 2022 in Los Angeles, California at the Los Angeles Convention Center.

From Beckman Coulter Life Sciences 20 Oct 2022

Scientists investigate the antibody titers post-mRNA COVID-19 booster vaccine in the elderly

The coronavirus 2019 disease (COVID-19) pandemic has affected millions worldwide and claimed multiple lives.

6 Oct 2022

Eligibility criteria lack clarity, justification for excluding people with disabilities from clinical trials

Despite constituting the largest minority group in the U.S. and expressing interest in participating in clinical trials, people with disabilities remain excluded.

3 Oct 2022

Does high vaccine coverage among the adult population grant the unvaccinated younger population indirect protection against SARS-CoV-2?

Researchers investigated whether the mass vaccination of the adult population of Schwaz, Austria, against SARS-CoV-2 conferred an indirect protective effect on the proportion of unvaccinated children in the population.

3 Oct 2022

At this recovery center, police cope with the mental health costs of the job

Ken Beyer can't think of a day in the past few months when his phone didn't flutter with calls, text messages, and emails from a police department, a sheriff's office, or a fire station seeking help for an employee.

27 Sep 2022

Is there any impact of COVID-19 vaccines on the fertility of men and women of reproductive age?

Researchers assessed the impact of SARS-CoV-2 vaccines on human fertility.

19 Sep 2022

COVID-19 vaccine safety concerns result in lower vaccination rates among pregnant individuals in the United States

In a new study, researchers evaluated the factors associated with lower coronavirus disease 2019 (COVID-19) vaccination rates among pregnant individuals in the United States (U.S.).

15 Sep 2022

Targeting the Notch pathway with gamma secretase inhibitor improves outcomes in patients with rare cancers

Significant improvement in progression-free survival and response rate combined with reduced symptoms and better quality of life are reported as outcomes of a new treatment approach for patients with desmoid tumors, which are benign, but locally aggressive and invasive soft tissue tumors.

12 Sep 2022

Researchers explore whether non-monetary benefits can improve NHS nursing staff retention

The House of Commons Committee on Health and Social Care recently described the NHS as being in the grip of the "greatest workforce crisis in its history", which is likely to have serious consequences for patient care.

7 Sep 2022

New OCTARAY™ Mapping Catheter with TRUEref™ Technology from Biosense Webster

The OCTARAY™ Mapping Catheter with TRUEref™ Technology provides physicians with the precise information needed for catheter ablation procedures that treat cardiac arrhythmias.

From Johnson & Johnson 7 Sep 2022

New study estimates how long people with mild COVID-19 are infectious

A new study of 57 people with mild COVID-19 estimates how long people are infectious for and when they can safely leave isolation.

19 Aug 2022

Study highlights the lack of evidence-based clinical management guidelines for monkeypox

A dearth of high quality, up to date clinical guidance on monkeypox may be hampering effective and safe treatment of the infection around the world, concludes a review of what's available to guide patient care and published in the open access journal BMJ Global Health.

18 Aug 2022

New method can modify an entire substance class of medically relevant natural products

The use of the element fluorine to modify active substances is an important tool in modern drug development.

5 Aug 2022

Study explores experiences of speech and language therapists using voice-assisted technology

JMIR Publications recently published "Speech and Language Practitioners' Experiences of Commercially Available Voice-Assisted Technology: Web-Based Survey Study" in JMIR Rehabilitation and Assistive Technologies which reported the professional experiences of UK speech and language therapists using voice-assisted technology (VAT) (e.g. Alexa, Siri) with their clients to identify the potential applications and barriers to VAT adoption and thereby inform future directions of research.

2 Aug 2022

Insights into molecular folding of AAT protein will help develop new therapies for alpha-1 antitrypsin deficiency

In a major new development in the quest to develop better gene therapies with which to treat a host of diseases, researchers at the University of Massachusetts Amherst and UMass Chan Medical School recently announced that they have mapped the expression and maturation of the protein alpha-1 antitrypsin (AAT) with unprecedented clarity.

25 Jul 2022

FTC official: Antitrust push in health care must focus on a merger’s ‘human impact’

President Joe Biden has ordered the Federal Trade Commission to combat consolidation in the health care industry, saying that it is driving up prices for consumers and limiting their access to care.

18 Jul 2022

New insights on measuring and valuing children's health-related quality of life

Value in Health, the official journal of ISPOR-;the professional society for health economics and outcomes research, announced today the publication of a series of articles providing new insights on measuring and valuing children's health-related quality of life.

5 Jul 2022