Hepatology News and Research

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Hepatology is the branch of medicine that incorporates study of liver, gallbladder, biliary tree and pancreas as well as management of their disorders.

Study shows that high-fat diets correlate to a chronic inflammatory state in the liver,

Mice that were fed diets high in fat and sugar developed immune system abnormalities in their livers, including reduced numbers of natural killer T (NKT) cells. These diet-related changes may contribute to obesity-related liver disease, according to a new study.

3 Oct 2005

Physical activity may reduce gastrointestinal symptoms in people who are obese

In a study published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, researchers found that a high body mass index (BMI) and lack of physical activity were associated with an increase in GI symptoms such as stomach pain, diarrhea, constipation and irritable bowel syndrome (IBS).

3 Oct 2005

Study suggests cirrhosis and liver disease nearly inevitable for people with hep C

Nearly 80 percent of chronic hepatitis C sufferers who have the disease for several decades will develop cirrhosis or end-stage liver disease later in life, according to a study published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology.

1 Sep 2005

Elevated blood lactate levels may indicate poor prognosis in liver failure

A new study on fulminant hepatic failure (FHF), a sudden and severe shutdown of the liver, examined ways of determining early on whether patients would benefit from a transplant as opposed to responding to other medical treatment. The results showed that elevated blood lactate levels indicate a poor prognosis and thus the need for a transplant.

28 Aug 2005

Susceptibility to Hepatitis A in patients with chronic liver disease due to Hepatitis C virus infection: missed opportunities for vaccination

A new study examining whether patients with chronic Hepatitis C virus (HCV) were routinely vaccinated against Hepatitis A virus (HAV) found that vaccination rates were low, even though HAV vaccination is recommended for patients with chronic liver disease.

23 Aug 2005

Study examines the incidence and risk factors associated with Hepatitis C infection in rural Egypt

The prevalence of antibodies to Hepatitis C Virus (HCV) in Egypt is among the highest in the world. From the 1950s until 1982 hundreds of thousands were infected during mass campaigns to control schistosomiasis (a parasitic disease) using mass therapy with intravenous antimony compounds, but little is known about current risk factors and rates of transmission.

23 Aug 2005

Alendronate combined with calcium and vitamin D almost completely prevented further bone loss in the first 4 months afte liver transplant

A new study found that the drug used to treat osteoporosis, when used in combination with calcium and vitamin D, can prevent the additional bone loss that commonly occurs after liver transplants. The treatment also helped stabilize bone loss in patients who already had osteoporosis, and helped improve their bone mineral density (BMD).

20 Jul 2005

A study analyzes the most important factors leading to death or liver transplant in drug-induced liver disease

Drug-induced liver disease (DILD), a potential complication seen with some medications, is usually not life-threatening, but may occasionally be more severe with a high mortality, requiring a liver transplant in selected cases.

18 Jul 2005

Pillcam enables Jefferson Physicians to diagnose diseases of esophagus without using endoscope

Most digestive disease specialists will tell you that patients would rather suffer from heartburn and other diseases of the upper GI system than undergo a very effective but also potentially uncomfortable and relatively invasive procedure to diagnose their problem.

9 Jun 2005

First study to examine liver injury in patients with obstructive sleep apnea (OSA)

Many patients with obstructive sleep apnea (OSA) are obese and therefore at risk of having fatty liver, a condition in which fat accumulates in the liver cells. But the link between OSA and liver injury independent of weight has yet to be examined.

25 May 2005

Smoking may have a devastating effect on gastrointestinal health

Smoking may have a devastating effect on gastrointestinal health and increase a person's risk of developing pancreatic and liver cancer, according to new research presented today at Digestive Disease Week 2005 (DDW). Furthermore, data from the Nurses' Health Study shows that meat intake and smoking play a part in significantly increasing a woman's risk of colorectal cancer.

17 May 2005

Grapefruit have strong antioxidant properties that can have healing effects on stomach ulcers

Extracts of the popular diet item grapefruit have strong antioxidant properties that can have healing effects on stomach ulcers, according to a new study presented today at Digestive Disease Week 2005 (DDW).

17 May 2005

Use of a common type of antidepressant may increase gastrointestinal (GI) bleeding

In fact, the study suggests that the increase is similar to that associated with the use of non-steroidal anti-inflammatory drugs (NSAIDs, known as pain relievers). DDW is the largest international gathering of physicians, academics and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

17 May 2005

Statin chemoprevention with minimal surveillance could prevent 96 percent of colon cancers

Ulcerative colitis affects about one out of every 2,000 Americans, and after living with the disease for 30 years, nearly 22 percent of those people will develop colon cancer.

16 May 2005

Abnormal liver tests in a Mediterranean population

recent population-based study in a small town in Southern Italy found that one in eight residents had abnormal liver tests.

26 Apr 2005

Fish oil, soluble fiber and antioxidants reduces need for traditional ulcerative colitis treatment

According to a study published in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, a nutritionally complete oral supplement enriched with fish oil, soluble fiber and antioxidants reduces reliance on traditional therapies for people with ulcerative colitis.

6 Apr 2005

Patients with Hepatitis C have a significant decrease in their health-related quality-of-life

Patients with Hepatitis C virus (HCV) have a significant decrease in their health-related quality-of-life (HRQOL), although treatment success can mitigate this negative effect.

28 Mar 2005

Statins appear to be safe for people with fatty liver disease

Statins appear to be safe for people with fatty liver disease who could benefit from their cholesterol-lowering capabilities, concludes a review paper published in the April 2005 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD).

28 Mar 2005

Alcohol relapse adversely affects liver transplant survival

A new study on how alcohol relapse affects survival rates after liver transplants found that it adversely affected survival rates only after 10 years. The decrease in survival rates may, however, be due to other alcohol-related diseases.

22 Mar 2005

Important advance in our understanding of colorectal cancer

An international team of medical scientists has made an important advance in our understanding of the second most fatal form of cancer in the industrialized world. Professor Jeremy R. Jass, who holds a Canada Research Chair in Gastrointestinal Pathology at McGill University in Montreal

3 Mar 2005

Hepatology News and Research

Further Reading

Study shows that high-fat diets correlate to a chronic inflammatory state in the liver,

Physical activity may reduce gastrointestinal symptoms in people who are obese

Study suggests cirrhosis and liver disease nearly inevitable for people with hep C

Elevated blood lactate levels may indicate poor prognosis in liver failure

Susceptibility to Hepatitis A in patients with chronic liver disease due to Hepatitis C virus infection: missed opportunities for vaccination

Study examines the incidence and risk factors associated with Hepatitis C infection in rural Egypt

Alendronate combined with calcium and vitamin D almost completely prevented further bone loss in the first 4 months afte liver transplant

A study analyzes the most important factors leading to death or liver transplant in drug-induced liver disease

Pillcam enables Jefferson Physicians to diagnose diseases of esophagus without using endoscope

First study to examine liver injury in patients with obstructive sleep apnea (OSA)

Smoking may have a devastating effect on gastrointestinal health

Grapefruit have strong antioxidant properties that can have healing effects on stomach ulcers

Use of a common type of antidepressant may increase gastrointestinal (GI) bleeding

Statin chemoprevention with minimal surveillance could prevent 96 percent of colon cancers

Abnormal liver tests in a Mediterranean population

Fish oil, soluble fiber and antioxidants reduces need for traditional ulcerative colitis treatment

Patients with Hepatitis C have a significant decrease in their health-related quality-of-life

Statins appear to be safe for people with fatty liver disease

Alcohol relapse adversely affects liver transplant survival

Important advance in our understanding of colorectal cancer

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Why use light scattering to analyze proteins and viral vectors?

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