Urea Cycle News and Research

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Urea cycle disorders are congenital diseases that are caused by a dysfunctional urea cycle. The genetics and biochemistry of these disorders have been extensively studied. They are the result of a deficiency of one of the six enzymes that catalyze the various biochemical reactions in the urea cycle which converts ammonia to urea for removal via urine.
Grant supports gene-editing research for rare metabolic diseases

Grant supports gene-editing research for rare metabolic diseases

Study reveals new insights into urea cycle's role in fatty liver disease

Study reveals new insights into urea cycle's role in fatty liver disease

Diet-derived molecules identified as main drivers of young-onset colorectal cancer risk

Diet-derived molecules identified as main drivers of young-onset colorectal cancer risk

IU research sheds light on urea cycle defects and fatty liver disease

IU research sheds light on urea cycle defects and fatty liver disease

Harnessing immune enhancement to combat drug-resistant tuberculosis

Harnessing immune enhancement to combat drug-resistant tuberculosis

Emerging trends in wearable breath sensors aim at personalized healthcare solutions

Emerging trends in wearable breath sensors aim at personalized healthcare solutions

A computational model identifies metabolites associated with Parkinson's disease

A computational model identifies metabolites associated with Parkinson's disease

New discovery can revolutionize the diagnosis and treatment of Alzheimer's disease

New discovery can revolutionize the diagnosis and treatment of Alzheimer's disease

Researchers develop point-of-care device to facilitate monitoring of hereditary and hepatic metabolic disorders

Researchers develop point-of-care device to facilitate monitoring of hereditary and hepatic metabolic disorders

Single-nucleus RNA sequencing and spatial transcriptome atlas of COVID-19 livers

Single-nucleus RNA sequencing and spatial transcriptome atlas of COVID-19 livers

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Study pinpoints a three-pronged approach that makes liver cancer cells stop growing

Researchers generate and characterize the hepatic organoid culture system

Researchers generate and characterize the hepatic organoid culture system

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

Untargeted metabolomics profiling can improve diagnosis of metabolic disorders in newborns

Researchers identify a common mechanism underlying diverse brain disorders

Researchers identify a common mechanism underlying diverse brain disorders

Researchers use base editing to sustainably lower high LDL cholesterol levels

Researchers use base editing to sustainably lower high LDL cholesterol levels

Minigenes produced by CRISPR combat liver disease in mice

Minigenes produced by CRISPR combat liver disease in mice

Arginine depletion could form the basis for potential rheumatoid arthritis therapies

Arginine depletion could form the basis for potential rheumatoid arthritis therapies

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Key mechanism identified for how antiviral immune responses reprogram liver metabolism

Ammonia levels do not guide clinical management of hepatic encephalopathy in cirrhotic patients

Ammonia levels do not guide clinical management of hepatic encephalopathy in cirrhotic patients

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