Acute Coronary Syndrome News and Research

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Novel anti-oxidant and anti-inflammatory agent reduces coronary events

Heart attacks are caused by a build-up and instability of plaque in the coronary arteries, which is often a result of chronic inflammation of the blood vessel walls.

31 Mar 2007

Medications plus lifestyle changes work as well as angioplasty to reduce deaths in stable heart-disease patients

Coronary revascularization with stenting or balloon angioplasty combined with optimal medical therapy is no more effective in preventing a heart attack, other major cardiovascular events or death in patients with stable heart disease, than optimal medical therapy alone, results of a new study conducted in 50 hospitals in the U.S. and Canada has shown.

27 Mar 2007

Simple blood test for NT-proBNP level may help predict cardiovascular events

A blood test for patients with coronary heart disease could help predict their risk for subsequent cardiovascular events or death, according to a study in the January 10 issue of JAMA: The Journal of the American Medical Association.

9 Jan 2007

High levels of two proteins in the bloodstream indicate need for action to avoid heart attack

Researchers working to decode chemical SOS signals sent out by disease-damaged hearts believe they now know better when to aggressively clear clogged arteries and when medical procedures may be unnecessary and even harmful.

12 Sep 2006

Redefining myocardial infarction for the 21st century

World Congress of Cardiology Report - Progress in the identification and quantification of biochemical markers of myocardial injury have led to a redefinition of myocardial infarction (MI).

5 Sep 2006

The murine abdominal adipose stromal cell compartment supports the differentiation into endothelial, but not into hematopoietic progenitor cells

World Congress of Cardiology Report - Post-infarct regeneration of the damaged myocardium is critical for treatment of patients with acute coronary syndrome or myocardial infarction.

5 Sep 2006

Preventing bleeding is key to the treatment of acute coronary syndromes

On Monday, September 4 and Tuesday, September 5 at the World Congress of Cardiology, Dr. Christopher Granger presented data stressing the importance of prevention of bleeding as a key objective in treatment of acute coronary syndromes.

5 Sep 2006

Improvements needed in China heart care

Inequitable and cost-inefficient allocation of scarce resources has been found to be a key problem in the management of heart attack and severe angina patients in China, according to the results of a study announced today at the World Congress of Cardiology in Barcelona, Spain.

4 Sep 2006

FDA approves Plavix for STEMI heart attacks

The Food and Drug Administration (FDA) today approved the use of Plavix (clopidogrel bisulfate) for patients who have had a type of heart attack called acute ST-segment elevation myocardial infarction (STEMI), who are not going to have coronary artery repair (angioplasty).

17 Aug 2006

Growing old with a partner a healthier option

According to new research from Denmark older people who live alone are twice as likely to suffer serious heart disease than those who live with a partner.

13 Jul 2006

Study calls for more consistent use of anti-clotting medications in women

High-risk women with acute coronary syndrome benefit as much as men from a trip to the cardiac cath lab shortly after being hospitalized, according to a study reported recently at the Society for Cardiovascular Angiography and Interventions (SCAI) 29th Annual Scientific Sessions in Chicago.

17 May 2006

Sildenafil improves blood flow after heart attack in an animal model

Dogs treated with sildenafil, a drug most commonly used to treat erectile dysfunction, had better blood flow in coronary arteries than control animals, following an induced artery obstruction and treatment that modeled a heart attack and standard medical care given to people

13 Apr 2006

New brain chemical test to predict heart attack yet appropriately used

A new brain chemical test that predicts which patients with heart attack symptoms are at higher risk of dying is paradoxically not being used in younger, healthier patients who could benefit the most from the prognostic information provided by this test

21 Mar 2006

Fondaparinux significantly reduces risk of death for heart attack patients

Heart attack patients who have a certain pattern on an electrocardiogram significantly reduced their risk of death and having another heart attack at 30 days with the medication fondaparinux, without an increased risk of bleeding and strokes

15 Mar 2006

Researchers evaluate efficacy, safety of anti-clotting drugs

Patients admitted to the hospital with an acute coronary syndrome (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention, or PCI.

15 Mar 2006

The safety and effectiveness of fondaparinux for heart attacks

The results of a large international cardiovascular trial will shed light on whether the addition of a new drug that prevents blood clotting, or thrombosis, can improve the treatment of the most serious form of heart attacks.

15 Mar 2006

Clopidogrel reduces risk of adverse events for patients with acute coronary syndromes undergoing balloon angioplasty

Patients with acute coronary syndromes who were pre-treated with the anti-platelet agent clopidogrel before undergoing a procedure such as balloon angioplasty or stent placement had a reduced risk of adverse events if they received the anti-clotting drug abciximab

14 Mar 2006

Angina drug finally gets the ok

U.S. regulators have granted approval for the drug Ranexa in the treatment of chronic angina.

31 Jan 2006

Coffee may impair peak heart function

In healthy volunteers, the equivalent of two cups of coffee reduced the body's ability to boost blood flow to the heart muscle in response to exercise, and the effect was stronger when the participants were in a chamber simulating high altitude, according to a new study in the Jan. 17, 2006, issue of the Journal of the American College of Cardiology.

16 Jan 2006

Lowering of LDL level shows limited benefit for patients with previous heart attack

Patients who have had a heart attack and are treated with a high dose of a statin drug did not have significant reduction in the primary outcome of major cardiac events (coronary death, nonfatal acute heart attack, or cardiac arrest with resuscitation), but did appear to have reduced risk when certain secondary outcomes (composite end points of any coronary heart disease event) were examined, according to a study in the November 16 issue of JAMA.

26 Nov 2005