Adenine News and Research

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Adenine is one of the four bases in DNA that make up the letters ATGC, adenine is the "A". The others are guanine, cytosine, and thymine. Adenine always pairs with thymine.

The link between androgens and COVID-19

A new paper examines the association between androgens and COVID-19, as revealed by the research carried out on this topic throughout the pandemic.

20 May 2022

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the mutations in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) non-structural protein 15 (Nsp-15).

16 May 2022

Researchers find gene that shapes mutation rate in mice

Every organism is born with a few mutations in their genome that differ genetically from both of their parents.

11 May 2022

Study identifies a protein in Mycobacterium tuberculosis that contributes to drug tolerance

Weill Cornell Medicine researchers have identified a protein in Mycobacterium tuberculosis (Mtb) that contributes to drug tolerance, a phenomenon that allows bacteria to survive treatment with drugs that would normally kill them.

4 May 2022

Researchers develop new platform capable of mitochondrial DNA editing

Researchers from the Center for Genome Engineering within the Institute for Basic Science developed a new gene-editing platform called transcription activator-like effector-linked deaminases, or TALED.

25 Apr 2022

MOFs could help improve the delivery of genetic cargo into target cells

Hybrid material helps ferry genetic cargo to target cells. An emerging type of material called a metal-organic framework(MOF) could help improve the delivery of genetic material for treating disease.

10 Apr 2022

Researchers discover a cell plasticity and inflammation driving druggable copper-signaling pathway

A new study identified mechanisms regulating immune cell plasticity to develop new therapeutics.

31 Mar 2022

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

High-grade serous carcinoma is the most aggressive form of ovarian cancer and accounts for the majority of advanced-stage cases.

16 Mar 2022

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Researchers studied how the mRNA-based BNT162b2 COVID-19 vaccine altered the biochemical composition of glial and glioma brain cells in vitro.

8 Mar 2022

Nicotinamide riboside supplement shows promise as a potential therapy for Parkinson’s disease

Nicotinamide riboside (NR) is amember of the vitamin B3 family, which can be found in foods like fruits, vegetables, meat, and milk. It is also used as a nutritional supplement to boost cellular levels of NAD (nicotinamide adenine dinucleotide).

2 Mar 2022

Peripubertal stress leads to increase in adipose tissue and reduces sociability

Between the end of childhood and the beginning of adolescence, there is a critical window of time referred to as "peripuberty".

2 Mar 2022

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Researchers from different countries performed a meta-analysis of real-world cross-cohorts and provided an association of the gut microbiome with immune checkpoint inhibitors response in patients with advanced melanomas.

2 Mar 2022

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Researchers demonstrated that the SARS-CoV-2 viroporins precipitate cytokine storm via the alteration of mitochondrial physiology in severe COVID-19.

24 Feb 2022

Study uses Promega LMR MSI Analysis System to detect microsatellite instability in multiple cancers

Researchers from Johns Hopkins University have shown that a new panel of long mononucleotide repeats might offer advantages over traditional microsatellite instability detection methods in certain types of solid tumors.

7 Feb 2022

New method may be effective at quantifying DNA adenine methylation in complex organisms

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.

3 Feb 2022

Adenine News and Research

The link between androgens and COVID-19

Characterizing SARS-CoV-2 non-structural protein 15 endoribonuclease variants

Researchers find gene that shapes mutation rate in mice

Study identifies a protein in Mycobacterium tuberculosis that contributes to drug tolerance

Researchers develop new platform capable of mitochondrial DNA editing

MOFs could help improve the delivery of genetic cargo into target cells

Researchers discover a cell plasticity and inflammation driving druggable copper-signaling pathway

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

Effect of COVID-19 mRNA vaccine on in vitro glial cells of the brain studied by Raman spectroscopy and imaging

Nicotinamide riboside supplement shows promise as a potential therapy for Parkinson’s disease

Peripubertal stress leads to increase in adipose tissue and reduces sociability

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

SARS-CoV-2 viroporins mediate cytokine storm via mitochondrial permeability transition pore

Study uses Promega LMR MSI Analysis System to detect microsatellite instability in multiple cancers

New method may be effective at quantifying DNA adenine methylation in complex organisms

Virus-like particles as delivery vehicles for gene-editing

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Long-read RNA sequencing identifies important host immune responses during SARS-CoV-2 infection

Genomic study of furin cleavage sites validates the natural evolutionary origin of SARS-CoV-2 in bats

Nucleoside modifications suppress the potential of RNA to activate dendritic cells

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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