Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Damaging effects of blue light exposure worsen with age

The damaging effects of daily, lifelong exposure to the blue light emanating from phones, computers and household fixtures worsen as a person ages, new research by Oregon State University suggests.

27 Jul 2022

Scientists explore SARS-CoV-2 spike protein and platelet-activating factor

Researchers assessed the association between platelet-activating factor (PAF) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein.

25 Jul 2022

Study reveals new mechanism that regulates auditory sensitivity

A new study published in PNAS highlights a newly identified mechanism of how auditory sensitivity is regulated that could temporarily reduce sensitivity of the auditory system to protect itself from loud sounds that can cause irreversible damage.

22 Jul 2022

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Researchers studied open and closed conformations of the C-terminal of SARS-CoV-2 nucleocapsid (N) protein termed the NCTD.

19 Jul 2022

The global succinylation and protein abundance in SARS-CoV-2–infected cells

Researchers assessed the global succinylation of SARS-CoV-2-infected host cells.

14 Jul 2022

Bacterial infections cause sperm dysfunction via their outer membrane vesicles

A new study discusses the impact of Escherichia coli (E. coli) infection on sperm parameters.

13 Jul 2022

New approach could pave the way for development of pan-coronavirus antivirals

To put the COVID-19 pandemic in the rearview mirror and prevent other coronaviruses from causing havoc, the world needs an arsenal of measures to prevent and treat these infections.

13 Jul 2022

What are the biological features, prevention and control strategies against monkeypox?

Researchers elucidated the epidemiology and clinical presentation, biological features, pathogenicity and prevention and control strategies for monkeypox virus (MPXV) infections.

13 Jul 2022

Impaired cardiac metabolism linked to increased risk of fatal arrhythmias or sudden cardiac death

Adults with abnormal heart metabolism are up to three times more likely to experience life-threatening arrhythmias (an irregular heart rhythm), and MRI techniques could be used to detect the condition and predict future sudden cardiac death (SCD), according to a small, but rigorous study led by Johns Hopkins Medicine researchers.

11 Jul 2022

How does obesity affect the immune system?

A new study summarizes new findings on the immunoregulatory effects of excessive fat stores or malnutrition through Th2 cells.

4 Jul 2022

Identification of potent SARS-CoV-2 macrodomain inhibitors

A recent study posted to the bioRxiv* preprint server illustrated the optimization of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein 3 (NSP3) macrodomain (Mac) inhibitor based on structure.

30 Jun 2022

Novel nanoparticle therapeutics shows promise to fight solid tumors

Researchers from Wake Forest University School of Medicine have discovered a possible new approach to treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer.

14 Jun 2022

First-of-its-kind platform generates antitumor immunity and improves responses to checkpoint inhibitors

Researchers at The University of Texas MD Anderson Cancer Center have developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade.

30 May 2022

Scientists discover how immune proteins defend plants against invading microorganisms

Scientists from the Max Planck Institute for Plant Breeding Research and the University of Cologne, Germany, have discovered a novel biochemical mechanism explaining how immune proteins defend plants against invading microorganisms.

20 May 2022

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

A new study has revealed that ATV006, which is a 5′-hydroxyl-isobutyryl prodrug, possesses extraordinary oral pharmaco-kinetic (PK) profiles in rats and cynomolgus monkeys and exhibited significant antiviral activity against ancestral SARS-COV-2 strain as well as VOCs.

20 May 2022

Blood adenosine levels positively correlate to the white matter lesions in very low birth weight premature infants

Prematurity affects about 10% of pregnancies worldwide each year. In about 20% of very low birth weight (VLBW) premature infants, punctate white matter lesions (PWML) can be diagnosed at MRI at term equivalent age.

13 May 2022

Personalized text messaging program improves healthy lifestyle measures in heart attack survivors

A text messaging program successfully supported, informed and motivated people after a heart attack on how to prevent a second heart attack, according to new research published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

9 May 2022

Adenosine News and Research

Further Reading

Damaging effects of blue light exposure worsen with age

Scientists explore SARS-CoV-2 spike protein and platelet-activating factor

Study reveals new mechanism that regulates auditory sensitivity

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

The global succinylation and protein abundance in SARS-CoV-2–infected cells

Bacterial infections cause sperm dysfunction via their outer membrane vesicles

New approach could pave the way for development of pan-coronavirus antivirals

What are the biological features, prevention and control strategies against monkeypox?

Impaired cardiac metabolism linked to increased risk of fatal arrhythmias or sudden cardiac death

How does obesity affect the immune system?

Identification of potent SARS-CoV-2 macrodomain inhibitors

Novel nanoparticle therapeutics shows promise to fight solid tumors

First-of-its-kind platform generates antitumor immunity and improves responses to checkpoint inhibitors

Scientists discover how immune proteins defend plants against invading microorganisms

Study demonstrates that ATV006 is orally bioavailable and has potent efficacy against SARS-CoV-2

Blood adenosine levels positively correlate to the white matter lesions in very low birth weight premature infants

Personalized text messaging program improves healthy lifestyle measures in heart attack survivors

Proximity labeling to identify high-confidence SARS-CoV-2 interactors

Understanding sex differences in the pathophysiology of SARS-CoV-2 infection

Intranasal nanoparticle STING agonist with immunoantiviral activity against SARS-CoV-2 variants

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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