Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Researchers demystify interdomain communication pathway in Hsp70 protein

Using a combination of computational and experimental techniques, a research team at the University of Massachusetts Amherst led by molecular biologist Lila Gierasch has demystified the pathway of interdomain communication in a family of proteins known as Hsp70s - a top target of dozens of research laboratories trying to develop new anti-cancer drugs, antibiotics and treatments for Alzheimer's and Parkinson's diseases.

30 Aug 2017

LSU Health New Orleans to receive $735,000 for improving heart attack recovery

LSU Health New Orleans will receive $735,000 over two years to study the effectiveness of the first patented drug-eluting guidewire in preventing a complication that can occur following treatment of heart attacks with angioplasty.

28 Aug 2017

Adequate sleep and caffeine could help reduce postoperative pain

Sleep is essential for good mental and physical health, and chronic insufficient sleep increases the risk for several chronic health problems.

18 Aug 2017

Study elucidates how aerobic exercise protects the sick heart

Regular exercise is considered an important form of treatment for heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs.

18 Aug 2017

Scientists show that human heart's sinoatrial node is hardwired with backup system

There's good news when it comes to our heart's sinoatrial node (SAN), the body's natural pacemaker. Scientists at The Ohio State University Wexner Medical Center have shown the human SAN is hardwired with a backup system -- three diverse regions of pacemakers acting as batteries and up to five conduction pathways that act as wires to connect the signal to the atria.

27 Jul 2017

Novel model predicts single heart cell's response to dwindling supplies of oxygen

Time is of the essence when treating a patient undergoing a heart attack. Cardiac surgeons attempt to quickly stabilize the heart by applying reperfusion, a technique that restores oxygen to the heart by opening up blocked vessels with balloons and stents.

21 Jul 2017

Sterilization and cleaning methods leave residual contamination on ureteroscopes

The techniques used to clean and sterilize flexible ureteroscopes leave behind contamination including debris, residue, and bacteria, according to a new study being presented at the 44th Annual Conference of the Association for Professionals in Infection Control and Epidemiology.

14 Jun 2017

Clinical study tests 100-year-old drug in children with autism spectrum disorder

In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

26 May 2017

Georgia State researchers renew $2.3 million federal grant for diabetic vascular disease research

Dr. Ming-Hui Zou, director of the Center for Molecular & Translational Medicine and a Georgia Research Alliance Eminent Scholar in Molecular Medicine, has renewed a four-year, $2.3 million federal grant to study the role of an enzyme in causing diabetic vascular diseases and the molecular mechanism that leads to these diseases.

25 May 2017

Rat study reveals new treatment approach that could potentially prevent osteoarthritis

Maintaining the supply of a molecule that helps to nourish cartilage prevented osteoarthritis in animal models of the disease, according to a report published in Nature Communications online May 11.

11 May 2017

Contrary behavior by blood vessels in the brainstem is what keeps us breathing, research suggests

Certain blood vessels in the brainstem constrict when blood vessels elsewhere in the body would dilate. And that contrary behavior is what keeps us breathing, according to a new paper by UConn researchers published May 8 in eLife.

9 May 2017

X-ray study sheds new light on promising drug target

Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins adorning cell surfaces, which are the targets of the majority of pharmaceutical drugs.

5 Apr 2017

Research helps elucidate mechanisms behind low-level laser therapy in treating neuropathic pain

Low-level laser therapy has been shown by recent studies to be a non-invasive and effective alternative for treating neuropathic pain, a chronic condition caused by nerve damage, spinal cord injury or diseases such as diabetes.

28 Mar 2017

New stenting tool found to be less painful and cheaper than current methods

A new tool for assessing the narrowing of the heart's arteries was found to be as effective as current methods and less painful for patients.

21 Mar 2017

High-resolution images of protein complex performing first step in genome-replication dance captured

It's a good thing we don't have to think about putting all the necessary pieces in place when one of our trillions of cells needs to duplicate its DNA and then divide to produce identical daughter cells.

17 Mar 2017

Study identifies new role of cholesterol in regulating brain proteins

A study led by researchers at the Hospital del Mar Medical Research Institute and the Institute of Medical Physics and Biophysics at the Faculty of Medicine in Charité Hospital, Berlin, published in the journal Nature Communications, demonstrates that the cholesterol present in cell membranes can interfere with the function of an important brain membrane protein, through a previously unknown mode of interaction.

23 Feb 2017

Caffeine cannot prevent memory deficits linked to alcohol consumption, study finds

A study recently published in Frontiers in Behavioral Neuroscience indicates that despite its impact on alertness and concentration, caffeine cannot counteract the memory deficits that result from alcohol consumption.

20 Feb 2017

SLU scientist examines potential biomarkers for pain linked to debilitating health conditions

With new funding from The Mayday Fund, a Saint Louis University researcher will leverage her discovery of a pain pathway to determine if either of two key molecules can be used as biomarkers for pain associated with four debilitating health conditions: chemotherapy-induced peripheral neuropathy, endometriosis, interstitial cystitis and vulvodynia.

16 Feb 2017

Sleep helps recalibrate brain cells responsible for learning and memory, mice study shows

Studying mice, scientists at Johns Hopkins have fortified evidence that a key purpose of sleep is to recalibrate the brain cells responsible for learning and memory so the animals can "solidify" lessons learned and use them when they awaken -- in the case of nocturnal mice, the next evening.

3 Feb 2017

Current reprocessing techniques of endoscopes not consistently effective, study suggests

Current techniques used to clean endoscopes for reuse are not consistently effective, according to a study published in the February issue of the American Journal of Infection Control, the official journal of the Association for Professionals in Infection Control and Epidemiology.

1 Feb 2017