Adenosine News and Research

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Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a ß-N9-glycosidic bond.

Caffeine prevents multiple sclerosis-like disease in mice

Mice given caffeine equivalent to a human drinking six to eight cups of coffee a day were protected from developing experimental autoimmune encephalomyelitis (EAE), the animal model for the human disease Multiple Sclerosis (MS), according to researchers at Cornell University.

8 Apr 2008

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection

As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease.

7 Apr 2008

Rare genetic syndrome may hold key to cure for heat stroke

A genetic disorder that can cause a fatal rise in body temperature in some patients undergoing general anesthesia may hold the key to a cure for heat stroke, according to research published in the April 4 edition of the journal Cell.

4 Apr 2008

A biosensing nanodevice to revolutionize health screenings

One day soon a biosensing nanodevice developed by Arizona State University researcher Wayne Frasch may eliminate long lines at airport security checkpoints and revolutionize health screenings for diseases like anthrax, cancer and antibiotic resistant Staphylococcus aureus (MRSA).

26 Mar 2008

Study explains fundamental process of tumor growth

Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

14 Mar 2008

Cause of prolonged penile erection

Priapism (prolonged penile erection in the absence of sexual interest) is common in male individuals with sickle cell disease (SCD), a blood disorder characterized by abnormally shaped red blood cells.

14 Mar 2008

Study helps explain how tumor cells rapidly grow and proliferate

Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

13 Mar 2008

New insights into what happens on a molecular level during photosynthesis

In a technical advance that could allow researchers to watch cells as they act during the process of photosynthesis, scientists have developed a method that extends the power of fluorescence-mediated bio-imaging to see discrete pigments inside live cells of bacteria.

6 Mar 2008

Diabetes is rapidly increasing globally, and Asian Indians have the highest prevalence

The incidence of type 2 diabetes is rising, especially in urbanized parts of the world where sedentary lifestyles and obesity abound.

1 Mar 2008

Copy number variation may stem from replication misstep

Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic "template," said researchers at Baylor College of Medicine in Houston in a report that appears today in the journal Cell.

28 Dec 2007

New research alters concept of how circadian clock functions

Scientists from the University of Cambridge have identified a molecule that may govern how the circadian clock in plants responds to environmental changes.

14 Dec 2007

Neurofibromatosis 1 gene drives pivotal decision in early brain development

A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers at Washington University School of Medicine in St. Louis have found.

14 Nov 2007

Lungs' pressure needn't threaten heart transplant survival

Heart surgeons at Johns Hopkins say people who need heart transplants can largely avoid transplant failure due to elevated blood pressure in their lungs with the help of proper drug treatment.

6 Nov 2007

Adenoscan patent lawsuits settled

Astellas Pharma Inc., King Pharmaceuticals, Inc. and Teva Pharmaceutical Industries Ltd. have announced that U.S. subsidiaries of Astellas, along with Item Development AB and King have executed settlement agreements with one of Teva's subsidiaries on lawsuits filed in the United States against Teva's subsidiaries regarding their submission of an abbreviated new drug application (ANDA) for a generic version of Adenoscan (adenosine injection), a pharmacologic stress agent.

22 Oct 2007

Existing drugs may be useful in treating brain tumors

Scientists have shown how developing brain tumors can turn an encounter with a signaling molecule from a fatal experience for the tumor cells into a cue for their own growth and multiplication.

17 Oct 2007

Picking the right stress test for heart disease risk analysis

Stress tests are good front-line tests indicators of heart disease, but just how good depends on ordering the right one, researchers say.

12 Oct 2007

Researchers track how a single molecule of RNA or DNA unwinds

The process by which genes are duplicated is mysterious and complex, involving a cast of characters with diverse talents and the ability to play well with others in extremely close quarters.

27 Jul 2007

Schering-Plough announces licensing of Acadesine

Schering-Plough Corporation has announced the worldwide licensing of acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA), from PeriCor Therapeutics, Inc., a privately held, specialty biopharmaceutical company.

20 Jul 2007

Coffee protects against involuntary eye spasm

People who drink coffee are less likely to develop an involuntary eye spasm called primary late onset blepharospasm, which makes them blink uncontrollably and can leave them effectively ‘blind', according to a study published online ahead of print in the Journal of Neurology Neurosurgery and Psychiatry .

20 Jun 2007

Theophylline offers relief for unexplained chest pain

The discomfort caused by esophageal (non-cardiac) chest pain is often severe, driving many patients to emergency rooms and physicians' offices despite the fact that the ailment has no definable pathology.

10 May 2007