Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

AAN calls on all neurology patients, caregivers to participate in 2012 Neuro Film Festival

The American Academy of Neurology Foundation is calling on all neurology patients and caregivers to submit a short video to its 2012 Neuro Film Festival, telling their story about why more research is needed into finding cures for brain disorders.

30 Aug 2011

UCLA program helps improve seniors' self-perceived memory

Who hasn't forgotten someone's name, misplaced their glasses or walked into a room and not remembered why they entered? Normal age-related memory decline affects more than half of all seniors, and those over 80 are the most vulnerable.

30 Aug 2011

New insights into Lafora disease

Short-term energy storage in animal cells is usually achieved through the accumulation of glucose, in the form of long and branched chains, known as glycogen. But when this accumulation happens in neurons it is fatal, causing them to degenerate. This neuronal deterioration and death associated with glycogen accumulation is the hallmark of an extremely rare and progressive type of epilepsy known as Lafora disease (LD).

29 Aug 2011

PREVENT licenses Amorfix's ProMIS to develop vaccines against misfolded prion diseases

The Pan-Provincial Vaccine Enterprise Inc. (PREVENT), a national Centre of Excellence for Commercialization and Research (CECR), has signed an exclusive license with Amorfix Life Sciences Ltd. of Missisauga, Ontario for the use of their proprietary ProMIS technology in developing vaccines (active immunotherapy) for the treatment of diseases caused by the formation of misfolded prion.

29 Aug 2011

HH&S, CDC announce eight finalists for 2011 Sentinel for Health Awards

Hollywood, Health & Society, a program of the Norman Lear Center at the University of Southern California (USC) Annenberg School for Communication & Journalism and the Centers for Disease Control and Prevention (CDC), are announcing eight finalists for the Sentinel for Health Awards.

29 Aug 2011

Researchers identify molecule that can stop the formation of amyloid fibrils

A molecule which can stop the formation of long protein strands, known as amyloid fibrils, that cause joint pain in kidney dialysis patients has been identified by researchers at the University of Leeds.

29 Aug 2011

Yale scientists synthesize huperzine A to combat Alzheimer's

Scientists at Yale University have developed the first practical method to create a compound called huperzine A in the lab.

26 Aug 2011

MR spectroscopy reveals biochemical changes in brains of people at risk for Alzheimer's

A brain imaging scan identifies biochemical changes in the brains of normal people who might be at risk for Alzheimer's disease, according to research published in the August 24, 2011, online issue of Neurology-, the medical journal of the American Academy of Neurology.

25 Aug 2011

Scientists discover genetic switch to prevent neurodegenerative diseases

Scientists at Northwestern University report a surprising discovery that offers a possible new route for the treatment of neurodegenerative diseases. In a study of the transparent roundworm C. elegans, they found that a genetic switch in master neurons inhibits the proper functioning of protective cell stress responses, leading to the accumulation of misfolded and damaged proteins.

25 Aug 2011

HHS selects Mayo Clinic physician to chair advisory council on Alzheimer's

Ronald Petersen, M.D., Cadieux Director of the Mayo Alzheimer's Disease Research Center and the Mayo Clinic Study of Aging, was selected to chair the Advisory Council on Alzheimer's Research, Care, and Services. The group was announced by Health and Human Services (HHS) Secretary Kathleen Sebelius.

25 Aug 2011

New mouse brain atlas provides insight into how genes work in cerebral cortex

A new atlas of gene expression in the mouse brain provides insight into how genes work in the outer part of the brain called the cerebral cortex. In humans, the cerebral cortex is the largest part of the brain, and the region responsible for memory, sensory perception and language.

25 Aug 2011

Free Alzheimer's disease conference to take place on Sept. 17

University of Louisville faculty researchers and clinicians with expertise in polypharmacy, caregiving and more will join with a Washington-based geriatric researcher at a free conference examining Alzheimer's disease.

25 Aug 2011

People with Down syndrome have diminished optokinetic, vestibular reflexes

A scientist investigating why those with Down syndrome often have poor balance and motor coordination has found that key eye reflexes are substantially altered.

25 Aug 2011

KFDA approves IND for DP-b99 Phase III MACSI stroke study in Korea

D-Pharm Ltd., announced today that the Korean Food & Drug Administration (KFDA) approved the Investigational New Drug application for the Phase III MACSI study of DP-b99 in Korea. The IND has been submitted by D-Pharm's co-development partner in South Korea, Yungjin Pharmaceutical Company Ltd..

24 Aug 2011

First international conference on developmental, translational and clinical pharmacogenomics

The first international conference hosted by the University of South Florida College of Pharmacy will focus on ways to improve health care by customizing drug prescribing and treatment based on an individual's genetic makeup.

24 Aug 2011

Seeing provides the big picture, but exploration burns it into memory

Seeing and exploring both are necessary for stability in a person's episodic memory when taking in a new experience, say University of Oregon researchers.

23 Aug 2011

Scientists identify molecular pathway that plays a key role in stress-related DNA damage

Working closely with a team of researchers from Duke University, scientists from the Florida campus of The Scripps Research Institute have helped identify a molecular pathway that plays a key role in stress-related damage to the genome, the entirety of an organism's hereditary information.

23 Aug 2011

New report: Molecular imaging market to reach $6 billion by 2015

By 2015, it is anticipated that the molecular imaging (MI) market will achieve a value of over $6 billion, according to a new report on companiesandmarkets.com.

23 Aug 2011

Risk of Parkinson's disease increases with traumatic brain injury and exposure to pesticide paraquat

Traumatic brain injury has entered the public's consciousness as the silent, signature wound brought back by many of our military warriors from Iraq and Afghanistan. But such injuries don't only happen in warfare, they happen to civilians too. Think car crashes, a slip and fall, two football players colliding helmet to helmet.

22 Aug 2011

Cellular pathology of Lou Gehrig’s disease discovered

Researchers claim to have found a common cause behind the mysterious and deadly affliction of amyotrophic lateral sclerosis, better known as Lou Gehrig’s disease. The discovery could pave the way to new treatments for the devastating disorder whose victims include top physicist Professor Stephen Hawking.

22 Aug 2011