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FDA mandate to limit the dosage of acetaminophen linked to reductions in serious liver injury

A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver injury, according to a study led by investigators at the University of Alabama and Weill Cornell Medicine.

7 Mar 2023

Novel multimodal analgesia protocol following total knee arthroplasty provides pain relief without opioids

A study led by Vinod Dasa, MD, Professor of Orthopaedics at LSU Health New Orleans School of Medicine, reports that a novel surgical pain management strategy following total knee arthroplasty (TKA), or total knee replacement, provided pain relief without opioids.

27 Feb 2023

Dangers of recreational/medical cannabis use

Researchers describe the wide range of neurological effects associated with cannabis use.

26 Oct 2022

Study determines the impact of withholding nitrous oxide for labor analgesia

Birthing women denied nitrous oxide ('laughing gas') to relieve labor pain during the COVID-19 pandemic have turned to opioids instead, without any adverse outcomes for mother or child, according to a new study by Australian clinicians.

16 Aug 2022

Researchers find neural circuitry supporting mindfulness-induced pain relief

For centuries, people have been using mindfulness meditation to try to relieve their pain, but neuroscientists have only recently been able to test if and how this actually works.

8 Jul 2022

Scientists uncover neural mechanisms through which sound blunts pain in mice

An international team of scientists has identified the neural mechanisms through which sound blunts pain in mice.

7 Jul 2022

2022 monkeypox presents with new symptoms

In a recent study published in The Lancet Infectious Diseases, researchers described the clinical and demographical characteristics of monkeypox virus infections among individuals attending sexual health centers in the United Kingdom (UK).

6 Jul 2022

Review of cannabis use on reproductive health, pregnancy, and fetal outcomes

A recent study reviewed cannabis use on reproductive health, pregnancy, and fetal outcomes.

8 Jun 2022

Anesthetists play an integral role in reducing preventable maternal mortality in the UK

In a session at this year's Euroanaesthesia, Obstetric Anaesthesia Expert Dr Nuala Lucas (Northwick Park Hospital, London, UK) will examine the key messages for anesthesia practice from the UK's Maternal Mortality Reports which are produced annually to provide robust information about the causes of maternal deaths to promote learning and further reduce preventable maternal mortality in the UK and beyond.

6 Jun 2022

Study shows how a non-opioid approach successfully manages women's pain after C-section

For years, women recovering from cesarean section (C-section) deliveries have been given devices that let them, with a button, control the flow of opioid painkillers into their IV line. But as researchers and policymakers push to curb the use of opioids, clinicians are developing new strategies for treating pain after C-sections.

3 May 2022

Study: More than two-thirds of the patients recover from knee replacement without opioids

A retrospective case series study led by Dr. Vinod Dasa, Professor of Clinical Orthopaedics at LSU Health New Orleans School of Medicine, reports that more than two-thirds of the patients who underwent total knee replacement did not need opioids for postoperative pain.

25 Mar 2022

15 medical societies establish seven guiding principles for perioperative treatment of acute pain

The American Society of Anesthesiologists and 14 leading medical specialty organizations established seven guiding principles to better address the perioperative treatment of acute pain in complex surgical patients.

8 Mar 2022

Study reveals the thalamocortical mechanism for nostalgia-induced analgesia

Ever noticed that looking at photos of good times with family or friends diminishes the pain of your headache? Nostalgia has already been shown to be helpful with pain relief, and a new study has now revealed the thalamocortical mechanism for nostalgia-induced analgesia.

28 Feb 2022

Labor neuraxial analgesia associated with reduced risk of severe maternal morbidity

In a study of vaginal births in New York State hospitals, labor neuraxial analgesia – having an epidural or combined spinal and epidural-; was associated with a decreased risk of severe maternal morbidity.

22 Feb 2022

Stomach emptying is slower during labor but faster in women who receive an epidural analgesia

Physician anesthesiologists prefer that laboring women have an empty stomach because of the lower risk for aspiration (inhaling) of food in case general anesthesia for cesarean section becomes necessary.

2 Feb 2022

Researchers explore how opioids may have become so widely abused

Researchers may have uncovered new answers on how to create safer opioids. Design a new opioid to bypass the part of brain that feels pleasure, but retain the analgesic properties, which make opioids one of the most effective pain relievers.

15 Oct 2021

Breakthrough discovery could pave the way for new non-opioid painkillers to treat neuropathic pain

Monash University researchers have made a breakthrough discovery that could pave the way for the development of novel non-opioid painkillers to safely and effectively treat neuropathic pain.

8 Sep 2021

Pain monitoring technology can reduce intraoperative opioid consumption

A new study has shown that effective opioid-sparing anaesthesia with dexmedetomidine can be guided with NOL pain monitoring technology (Medasense, Israel). The study showed that the NOL monitor is able to detect the effect of dexmedetomidine on the patient's pain response and enable administration of less intraoperative opioids.

26 May 2021

New peptides allow cannabis-derived drugs to fight pain in mice without side effects

An international team, led by researchers from Pompeu Fabra University (UPF) in Barcelona, Spain, David Andreu and Rafael Maldonado, has developed a peptides family that allows delta-9-tetrahydrocannabinol (THC), the main component of Cannabis sativa, to fight pain in mice without side effects.

20 May 2021

Researchers harness the body's own ability to block pain

Fentanyl, oxycodone, morphine--these substances are familiar to many as a source of both pain relief and the cause of a painful epidemic of addiction and death.

26 Apr 2021