Analgesia News and Research

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RFA causes less post-procedural pain in patients with varicose veins: Study

Patients who received radiofrequency ablation for varicose veins reported less post-procedural pain than those treated with endovenous laser ablation. However, both groups reported the same clinical and quality of life improvements at six weeks.

17 May 2010

Postpartum hemorrhage increases 28% between 1995 and 2004

A new study of U.S. maternal outcomes after vaginal and cesarean deliveries published in the May 2010 issue of Anesthesia & Analgesia, a peer-reviewed academic journal, shows that between 1995 and 2004, postpartum hemorrhage (excessive blood loss after delivery) increased 28% in prevalence. Postpartum hemorrhage is one of today's most common complications for delivering mothers that according to the study, "markedly increases the odds of in-hospital mortality" and causes 19% of in-hospital maternal deaths.

7 May 2010

Advances in genetic research could help develop personalized pain medications

In the not too distant future, it may be possible to discern an individual's genetic predisposition to chronic pain conditions and treat them proactively to prevent lifetime afflictions, according to research presented today at the American Pain Society's (www.ampainsoc.org) annual scientific meeting.

7 May 2010

Study reveals changes in brain activity in response to withdrawal of life support

At a time when "donation after cardiac death" (DCD) has become an important approach to increasing the number of transplant organ donors, a provocative new study shows changes in brain activity occurring in response to withdrawal of life support, reports the May issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

5 May 2010

Anesthesiologist identifies two changes to standard of care to protect developing brains

Doctors at Children's National Medical Center have found that carbon monoxide levels in the blood of young children increase during routine general anesthesia. Anesthesiologists have found for the first time that, under certain circumstances, infants and children may be exposed to carbon monoxide during routine anesthesia resulting in a rise in the carbon monoxide levels in the child's blood.

5 May 2010

Additional pivotal Phase 3 trial data for MoxDuo IR released

QRxPharma announced today the release of additional pivotal Phase 3 trial data for MoxDuo IR, an immediate-release Dual-Opioid pain therapy. Required for New Drug Application submission with the United States Food and Drug Administration, this "combination rule" study compared the efficacy and safety profiles of MoxDuo IR against component doses of morphine and oxycodone alone for the management of moderate to severe post-operative pain following bunionectomy surgery.

5 May 2010

Conservative therapies need to be recommended over routine use of OTC cough/cold products in children

Despite their widespread use by parents and caregivers, over-the-counter (OTC) cold and cough medicines have carried a warning by the FDA since 2008, and still have the potential to cause serious adverse events in infants and children. Conservative therapies, including nasal suctioning, humidification, and nasal saline, should be recommended over routine use of OTC cough/cold products in infants and children, according to a new commentary published in the May 2010 issue of Otolaryngology - Head and Neck Surgery.

4 May 2010

Conservative therapies recommended over routine use of OTC cough/cold products in children

Despite their widespread use by parents and caregivers, over-the-counter cold and cough medicines have carried a warning by the FDA since 2008, and still have the potential to cause serious adverse events in infants and children. Conservative therapies, including nasal suctioning, humidification, and nasal saline, should be recommended over routine use of OTC cough/cold products in infants and children, according to a new commentary published in the May 2010 issue of Otolaryngology - Head and Neck Surgery.

3 May 2010

Scientific validity of traditional Chinese medicine for pain treatment receives support

The scientific validity of traditional Chinese medicine for pain treatment of pain received a nod of support in the May issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

3 May 2010

Codeine containing preparations lose their OTC status

It will get more difficult to procure Codeine based pain killers, cough syrups etc. from the local pharmacists from now on. There have been new restrictions over codeine based drugs like Nurofen Plus, Panadeine and Mersyndol which were initially sold over the counter but lost this OTC status with effect from May 1st 2010. The National Drugs and Poisons Schedule Committee formulated the changes during meetings in June and October last year.

2 May 2010

Researchers show how analgesia should be carried out for children and adolescents

Properly performed analgesia protects children from pain and traumatization. In the current issue of Deutsches Ärzteblatt International, Christoph Neuhäuser and his colleagues show how analgesia for children and adolescents should be carried out.

26 Apr 2010

Covidien launches EXALGO Extended-Release Tablets in the US

Covidien, a leading global provider of healthcare products, today introduced EXALGO™ (hydromorphone HCI) Extended-Release Tablets, (CII), the only extended-release hydromorphone treatment available in the United States. This proven therapy, combined with an innovative delivery system, provides opioid-tolerant patients suffering from moderate-to-severe chronic pain relief for 24 hours per dose.

26 Apr 2010

Techniques to protect organs during bypass surgery impair autoregulation, increase risk of stroke: Study

The standard practice of cooling and then rewarming a patient to prevent organ damage during cardiac bypass surgery may impair the body's mechanism that controls blood flow to the brain, potentially increasing the patient's risk of stroke, new research from Johns Hopkins suggests.

23 Apr 2010

CryoSTAT cold therapy for hemorrhoids

Revolutionary new CryoSTAT is here to put the fire out when it comes to hemorrhoids by treating them on contact with cold therapy which has a proven track record of providing instant relief with no mess.

20 Apr 2010

Pivotal preclinical data of YM BioSciences' CYT387 JAK1/2 inhibitor pre-published in Blood

YM BioSciences Inc., announced the pre-publication of pivotal preclinical data for CYT387, the company's highly selective and potent JAK1/2 inhibitor, currently in a Phase I/II trial for myelofibrosis.

19 Apr 2010

Alkermes submits VIVITROL sNDA for opioid dependence

Alkermes, Inc. today announced that it has submitted a supplemental New Drug Application (sNDA) for VIVITROL® (naltrexone for extended-release injectable suspension) to the U.S. Food and Drug Administration (FDA) for approval as a treatment for opioid dependence. The company requested a priority review for its sNDA and if granted by the FDA, it would mean a six month review timeline.

13 Apr 2010

New head-mounted display system lets anesthesiologists focus on monitoring data during surgery

A new head-mounted display system lets anesthesiologists keep an eye on critical monitoring data during surgery—without having to turn their attention away from the patient, reports a study in the April issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

6 Apr 2010

New formulation of controlled-release drug OxyContin approved

The U.S. Food and Drug Administration today approved a new formulation of the controlled-release drug OxyContin that has been designed to help discourage misuse and abuse of the medication.

6 Apr 2010

Hospira reaches legal settlement with Sanofi-Aventis over oxaliplatin injection patent litigation

Hospira, Inc., the world leader in generic injectable pharmaceuticals, today announced it has reached a legal settlement with Sanofi-Aventis to resolve patent litigation concerning Hospira's U.S. sales of its oxaliplatin injection, a generic version of Sanofi-Aventis' oncolytic agent, Eloxatin®.

2 Apr 2010

Conventional analgesics to drive acute pain market over the next decade

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, through 2018, the launches and uptake of reformulations of conventional analgesics will drive annual three percent growth in the acute pain drug market in the United States, France, Germany, Italy, Spain, the United Kingdom and Japan.

1 Apr 2010

Analgesia News and Research

RFA causes less post-procedural pain in patients with varicose veins: Study

Postpartum hemorrhage increases 28% between 1995 and 2004

Advances in genetic research could help develop personalized pain medications

Study reveals changes in brain activity in response to withdrawal of life support

Anesthesiologist identifies two changes to standard of care to protect developing brains

Additional pivotal Phase 3 trial data for MoxDuo IR released

Conservative therapies need to be recommended over routine use of OTC cough/cold products in children

Conservative therapies recommended over routine use of OTC cough/cold products in children

Scientific validity of traditional Chinese medicine for pain treatment receives support

Codeine containing preparations lose their OTC status

Researchers show how analgesia should be carried out for children and adolescents

Covidien launches EXALGO Extended-Release Tablets in the US

Techniques to protect organs during bypass surgery impair autoregulation, increase risk of stroke: Study

CryoSTAT cold therapy for hemorrhoids

Pivotal preclinical data of YM BioSciences' CYT387 JAK1/2 inhibitor pre-published in Blood

Alkermes submits VIVITROL sNDA for opioid dependence

New head-mounted display system lets anesthesiologists focus on monitoring data during surgery

New formulation of controlled-release drug OxyContin approved

Hospira reaches legal settlement with Sanofi-Aventis over oxaliplatin injection patent litigation

Conventional analgesics to drive acute pain market over the next decade

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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