Cancer promoting gene identified

21. November 2009 03:08

Virginia Commonwealth University Massey Cancer Center and VCU Institute of Molecular Medicine researchers have identified a gene that may play a pivotal role in two processes that are essential for tumor development, growth and progression to metastasis. Scientists hope the finding could lead to an effective therapy to target and inhibit the expression of this gene resulting in inhibition of cancer growth. [More]

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Posted in: Medical Science News | Medical Condition News

Tags: Angiogenesis, Blood Vessel, Brain, Breast Cancer, Cancer, Cell, Education, Fibroblast, Genetics, Glioblastoma, Glioblastoma Multiforme, Glioma, Liver Cancer, Lung Cancer, Metastasis, Neuroblastoma, Prostate Cancer, Squamous Cell Carcinoma

Opiate-based painkillers can increase tumor-cell proliferation, says new study

19. November 2009 01:37

Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. [More]

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Posted in: Medical Condition News | Pharmaceutical News

Tags: Anesthesiology, Angiogenesis, Brain, Cancer, Cell, Cell Proliferation, Constipation, Life Expectancy, Lung Cancer, Metastasis, Morphine, Non-Small Cell Lung Cancer, Prostate Cancer, Small Cell Lung Cancer

Press conference highlights emerging treatments in pancreatic cancer

18. November 2009 03:30

As part of the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Thompson will moderate a press conference on emerging treatments in pancreatic cancer on Tuesday, Nov. 17, 2009, in Room 202 of the Hynes Convention Center in Boston, Mass., from 1:00 p.m. to 2:00 p.m. ET. [More]

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Posted in: Medical Condition News

Tags: Abraxane, Angiogenesis, Antibody, Avastin, Bevacizumab, Blood Vessel, Cancer, Cell, Chemotherapy, Dermatology, Gemcitabine, Gemzar, Gene Expression, Hospital, Liver Cancer, Metastasis, microRNA, Nanotechnology, Oncology, Paclitaxel, Pancreatic Cancer, Pathology, Photodynamic Therapy, Radiotherapy, VEGF

Study to test anti-tumor effects of AEOL 10150 initiated

18. November 2009 03:04

Aeolus Pharmaceuticals, Inc. announced today the initiation of a study to test the anti-tumor effects of AEOL 10150 when combined with radiation and chemotherapy in nude mice bearing human non-small cell lung cancer (NSCLC) xenografts. [More]

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Posted in: Medical Science News | Medical Condition News | Pharmaceutical News

Tags: Angiogenesis, Anti-Inflammatory, Antioxidant, Cancer, Cell, Chemotherapy, Epilepsy, Fibrosis, Hypoxia, Lung Cancer, Macrophage, Manganese, Non-Small Cell Lung Cancer, Oxidative Stress, Paclitaxel, Radiation Exposure, Radiation Therapy, Radiotherapy, Small Cell Lung Cancer, Stress, Toxicology, VEGF, Weight Loss

YM BioSciences presents preclinical results of its small molecule VDA at the AACR-NCI-EORTC conference

17. November 2009 07:55

YM BioSciences Inc., a life sciences product development company that identifies and advances a diverse portfolio of promising cancer-related products at various stages of development, announced that preclinical results for CYT997 were presented today in a poster by Cytopia Limited at the 2009 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics conference in Boston, Massachusetts. [More]

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Posted in: Drug Trial News | Medical Condition News

Tags: Analgesia, Angiogenesis, Antibody, Biotechnology, Cancer, Cisplatin, Dermatitis, Fentanyl, Immunology, Liposome, Monoclonal Antibody, Opioids, Xenograft

Bayer's NEXAVAR approved in over 70 countries for the treatment of liver cancer

17. November 2009 07:35

Bayer Inc. announced today that its international trial known as SHARP (Sorafenib HCC Assessment Randomized Protocol), led by Study Manager and Bayer Canada employee Tom Giannaris, has been selected as the winner in the 'Best International Trial' category for the Global Clinical Practice Journal Awards. [More]

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Posted in: Medical Condition News | Pharmaceutical News

Tags: Angiogenesis, Cancer, Cell, Cell Proliferation, Hepatitis B, Hepatocellular Carcinoma, Kidney Cancer, Kinase Inhibitor, Liver Cancer, Multiple Sclerosis, Nexavar, Oncology, Sorafenib

Scientists solve 50-year-old thalidomide puzzle

17. November 2009 06:13

Research into the controversial drug thalidomide reveals that the mechanism through which the drug causes limb defects is the same process which causes it to damage internal organs and other tissues. The article, published in Bio-Essays, outlines the challenges surrounding thalidomide research and claims that confirmation of a 'common mechanism' could lead to new treatments for Leprosy, Crohn's Disease, AIDS and some forms of cancer.. [More]

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Posted in: Pharmaceutical News

Tags: Angiogenesis, Cancer, Crohn's Disease, Leprosy, Multiple Myeloma, Thalidomide

AACR-NCI-EORTC conference highlights major expansion in cancer drug pipeline

17. November 2009 05:02

To highlight results of more recent research, the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics International Conference will host a press briefing on "Drugs in the Pipeline." Sara A. Courtneidge, Ph.D., D.Sc., professor and director of the Tumor Microenvironment Program, and director of academic affairs at the Burnham Institute for Medical Research, will moderate this press briefing. [More]

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Posted in: Medical Condition News | Pharmaceutical News

Tags: Acetylation, Adenosine, Amino Acid, Anemia, Angiogenesis, Autophagy, Blood Pressure, Breast Cancer, Cancer, Cediranib, Cell, Chemotherapy, Colorectal Cancer, Diarrhea, DNA, Gene Expression, Hematology, Leukemia, Myeloid Leukemia, Nausea, Oncology, Ovarian Cancer, Radiotherapy, Stem Cell, Stress, Vomiting

Genentech submits sBLAs to the FDA for Avastin

17. November 2009 03:36

Genentech, Inc., a wholly-owned member of the Roche Group, today announced that the company submitted two supplemental Biologics License Applications (sBLAs) to the U.S. Food and Drug Administration (FDA) for Avastin® (bevacizumab) for the treatment of women who have not received chemotherapy for advanced (metastatic) HER2-negative breast cancer (first-line treatment). One sBLA is based on the Phase III study AVADO that investigated Avastin in combination with docetaxel chemotherapy. [More]

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Posted in: Women's Health News | Pharmaceutical News

Tags: Abdominal Pain, Angiogenesis, Anthracycline, Antibody, Avastin, Back Pain, Bevacizumab, Biotechnology, Birth Control, Blood Pressure, Blood Vessel, Bone, Brain, Breast Cancer, Cancer, Capecitabine, Cell, Chemotherapy, Congestive Heart Failure, Dehydration, Dermatitis, Diarrhea, Docetaxel, Fertility, Fistula, Headache, Heart Failure, Low Blood Pressure, Nausea, Nervous System, Paclitaxel, Pregnancy, Stroke, VEGF, Vomiting, Wound Healing

ThromboGenics and BioInvent International present phase I results of novel anti-cancer monoclonal antibody

17. November 2009 03:30

ThromboGenics NV and BioInvent International AB today announced positive results from a Phase I trial of their novel anti-cancer monoclonal antibody TB-403 in patients with advanced solid tumours. The results were presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in Boston, U.S. TB-403 was well tolerated with no reported dose limiting toxicity. These positive data support progression of TB-403 and further development. [More]

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Posted in: Drug Trial News | Medical Condition News

Tags: Angiogenesis, Antibody, Atherosclerosis, Biotechnology, Cancer, Metastasis, Monoclonal Antibody, Thrombosis

Targeting normal cells that surround cancer cells increases the effectiveness of traditional anti-cancer treatments

17. November 2009 01:58

Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute. [More]

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Posted in: Medical Science News | Medical Condition News

Tags: Angiogenesis, Avastin, Blood Vessel, Cancer, Cell, Collagen, Colon Cancer, Fibroblast, Lung Cancer, Vaccine

Pro-Pharmaceuticals announces financial results for the third quarter and first nine months of fiscal 2009

13. November 2009 09:14

Pro-Pharmaceuticals, Inc., a developer of galectin-targeted, carbohydrate therapeutic compounds to treat cancer and fibrosis, today reported its financial results for the third quarter and first nine months of fiscal 2009. These results are included in the Company’s Quarterly Report on Form 10-Q for the three- and nine-month periods ended September 30, 2009, which has been filed with the SEC. [More]

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Posted in: Business / Finance

Tags: Angiogenesis, Biotechnology, Cancer, Carbohydrate, Cell, Chemotherapy, Colorectal Cancer, Fibrosis, Galectins, Metastasis, New Drug Application

Researchers identify a new mechanism that inhibits the formation of new blood vessels

12. November 2009 02:00

Researchers at Uppsala University, in collaboration with colleagues in Sweden and abroad, have identified an entirely new mechanism by which a specific protein in the body inhibits formation of new blood vessels. Inhibiting the formation of new blood vessels is an important aspect of, for example, cancer treatment. The study is published in the November issue of the journal Molecular Cancer Research. [More]

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Posted in: Medical Science News

Tags: Angiogenesis, Biochemistry, Cancer

Acceleron Pharma commences Phase 1 clinical study of its novel angiogenesis inhibitor

4. November 2009 08:40

Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth of cells and tissues including red blood cells, bone, muscle, fat, and the vasculature, today announced the initiation of a Phase 1 clinical study of ACE-041, a novel angiogenesis inhibitor that binds to and prevents members of the TGF-β superfamily from signaling through the activin receptor-like kinase 1 (ALK1) receptor. [More]

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Posted in: Drug Trial News | Medical Condition News

Tags: Anemia, Angiogenesis, Blood Vessel, Bone, Cancer, Neuromuscular Disease, VEGF

Study: Short-term use of COX-2 inhibitors may help prevent gastric cancer

29. October 2009 03:17

Elevated expression of COX-2 is observed in a wide variety of human malignancies, including gastric cancer. Long-term high dose COX-2 inhibitors can inhibit gastric carcinogenesis in animal models, but the possible life-threatening cardiovascular adverse events limit its popular application. Therefore, it is important to evaluate the optimal intervention point of COX-2 inhibitors for inhibiting H. pylori-associated gastric carcinogenesis. [More]

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Posted in: Medical Science News | Medical Condition News

Tags: Angiogenesis, Cancer, Colorectal Cancer, Cox-2 Inhibitor, Esophageal Cancer, Gastritis, Gastroenterology, Hepatology, Hospital, Liver Cancer, Metastasis, Peptic Ulcer, Ulcer

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Angiogenesis News and Research

Cancer promoting gene identified

Opiate-based painkillers can increase tumor-cell proliferation, says new study

Press conference highlights emerging treatments in pancreatic cancer

Study to test anti-tumor effects of AEOL 10150 initiated

YM BioSciences presents preclinical results of its small molecule VDA at the AACR-NCI-EORTC conference

Bayer's NEXAVAR approved in over 70 countries for the treatment of liver cancer

Scientists solve 50-year-old thalidomide puzzle

AACR-NCI-EORTC conference highlights major expansion in cancer drug pipeline

Genentech submits sBLAs to the FDA for Avastin

ThromboGenics and BioInvent International present phase I results of novel anti-cancer monoclonal antibody

Targeting normal cells that surround cancer cells increases the effectiveness of traditional anti-cancer treatments

Pro-Pharmaceuticals announces financial results for the third quarter and first nine months of fiscal 2009

Researchers identify a new mechanism that inhibits the formation of new blood vessels

Acceleron Pharma commences Phase 1 clinical study of its novel angiogenesis inhibitor

Study: Short-term use of COX-2 inhibitors may help prevent gastric cancer

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