Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

Statins lessen heart attack risk

For patients with undiagnosed heart disease, taking medications known as statins and beta-blockers may mean the difference between suffering a heart attack as a first symptom versus experiencing mild chest pain.

24 Feb 2006

Genetic variations help predict risk for salt-induced high blood pressure

Researchers led by UVa Health System pathologist Robin Felder, Ph.D., have demonstrated that looking for several variations of genes that control blood pressure can predict the risk for high blood pressure caused by high levels of salt.

23 Feb 2006

New treatment trials for autosomal dominant polycystic kidney disease

The National Institutes of Health (NIH) and the PKD Foundation have launched two treatment trials for autosomal dominant polycystic kidney disease (ADPKD).

25 Jan 2006

Coronary artery disease patients consistently fail to take life saving drugs

Nearly half the coronary artery disease (CAD) patients in a seven-year study admitted they don’t consistently take beta blockers, cholesterol-lowering drugs and other medications that could extend their lives, researchers report in Circulation: Journal of the American Heart Association.

10 Jan 2006

Rates for new cases of kidney failure have stabilized

After 20 years of annual increases from 5 to 10 percent, rates for new cases of kidney failure have stabilized, according to new research from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). At the same time, dramatic racial disparities persist.

11 Oct 2005

GRK5 protein plays important role in hypertension

Researchers at Jefferson Medical College have implicated a protein called GRK5 as having an important role behind essential hypertension, which affects more than 65 million Americans.

5 Oct 2005

Governments considering reclassifying some drugs from prescription to over-the-counter status

Governments in several countries with public Pharmacare and in a few provinces in Canada are considering reclassifying some drugs from prescription to over-the-counter status. In a Canadian Medical Association Journal essay, Lynd and colleagues comment on the economic effects of such changes.

27 Sep 2005

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection.

19 Sep 2005

Part of largest randomised international trial program ever conducted in atrial fibrillation (AF) discontinued

Study treatments for the ACTIVE W trial of the ACTIVE (Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events) program have been discontinued due to a significant difference in efficacy, in favour of the standard oral anticoagulation (OAC) over antiplatelet therapy (clopidogrel plus aspirin).

6 Sep 2005

Nurse-led multidisciplinary programme can help coronary patients and their families to reduce their risk of major cardiovascular disease

Early results from the EuroAction hospital project, announced today at the European Society of Cardiology, demonstrate how a nurse-led multidisciplinary programme, organised in busy general hospitals, can help coronary patients and their families to reduce their risk of major cardiovascular disease (CVD).

5 Sep 2005

Chronic heart failure (CHF) is common, deadly, disabling, costly but fortunately - treatable

During the last ten to 15 years, treatment of CHF has been dramatically improved by pharmacological therapy and devices. Treatment also has become more complicated.

5 Sep 2005

GenoMed has announced that it successfully treated its thirteenth patient with presumed West Nile virus encephalitis

The patient is a previously healthy man from Aberdeen, South Dakota who developed fever and headache and was diagnosed by his physician as having West Nile virus on Monday of this week. South Dakota has about 50 times higher incidence of West Nile virus this summer than California.

1 Sep 2005

Designer molecules that combine metals such as copper with natural organic materials could treat diseases in the body

That's the finding of chemists at Ohio State University, who have successfully tested such molecules against portions of HIV and Hepatitis C virus RNA in the laboratory. They've also created molecules that act like ACE, or angiotensin-converting enzyme, inhibitors - drugs that are used to lower blood pressure.

30 Aug 2005

Genes interact with behavior to affect how well people move

Genes can keep elderly people from benefiting equally from exercise, no matter how much effort they expend, according to research findings published in today's (Aug. 10) Journal of the American Medical Association.

11 Aug 2005

Certain gene variation associated with better mobility for older individuals who exercise

Older individuals with a certain gene variation who exercise are less likely to develop mobility limitations than individuals without the gene variation, according to a study in the August 10 issue of JAMA: The Journal of the American Medical Association.

10 Aug 2005

Enzyme involved in blood pressure regulation may also influence how the body responds to exercise

New research suggests why some older adults who exercise have better physical function than others. Surprisingly, researchers found that an enzyme involved in blood pressure regulation may also influence how the body responds to exercise.

9 Aug 2005

FDA approval for Diovan (Valsartan)

Novartis Pharmaceuticals Corporation announced today that the US Food and Drug Administration (FDA) approved Diovan (valsartan), the most prescribed ARB (angiotensin receptor blocker) in the US and worldwide, for a new indication to reduce cardiovascular death in patients at high risk (with left ventricular failure or left ventricular dysfunction) following a heart attack.

4 Aug 2005

GenoMed submits 50th provisional patent application

GenoMed announced today that the Company has submitted its 50th provisional patent application, a major milestone in any development stage company. GenoMed has so far been awarded two patents, one for treating acute kidney failure without dialysis, and another for hastening lung maturation in prematurely born infants.

26 Jul 2005

Study compares four standard measures for heart failure treatment

UCLA investigators found large gaps and marked variation in U.S. hospitals' heart failure treatment based on adherence to four standard quality measures. The study points to the need for hospitals to establish education programs and systems to improve quality of care for this patient population.

11 Jul 2005

Blood pressure enzyme linked to SARS virus, could help fight diseases that cause lung failure

Researchers in Austria say that an enzyme that regulates blood pressure is also involved in the SARS virus, and the discovery could lead to new ways of treating diseases that cause lung failure.