Angiotensin News and Research

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Angiotensin is an oligopeptide in the blood that causes vasoconstriction, increased blood pressure, and release of aldosterone from the adrenal cortex. It is a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.

VUMC-led trial demonstrates the inefficacy of two investigational drugs for treating severe COVID-19

Despite the success of vaccines for preventing COVID-19, and of drugs for treating the disease, outcomes for severely ill patients admitted to the hospital remains poor.

11 Apr 2023

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Researchers found antibodies that neutralize all current SARS-CoV-2 variants.

11 Apr 2023

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Researchers assess the efficacy of the human surfactant protein A against SARS-CoV-2 infectivity.

10 Apr 2023

Study highlights the potential long-term neurological effects post-COVID-19

Researchers studied the presence of the SARS-CoV-2 spike protein in the skull-meninges-brain (SMB) axis.

10 Apr 2023

Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission

A study investigating risk factors and vectors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) household transmission reveals that the presence of the virus on the hands of primary and secondary cases and on frequently-touched surfaces is associated with transmission risk. The study is published in the journal THE LANCET Microbe.

9 Apr 2023

Study reviews the diagnosis and treatment of acute myocarditis

Scientists have recently reviewed and summarized the evidence regarding diagnosing and treating acute myocarditis.

6 Apr 2023

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Researchers assessed the ability of spike proteins from 24 animal or human coronaviruses to utilize angiotensin-converting enzyme 2.

5 Apr 2023

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

Researchers assessed the extent of SARS-CoV-2 Omicron VOC BA.5 sub-VOC infection-associated brain infection and death.

5 Apr 2023

The association between neutralizing antibody response breadth and long COVID symptoms

Researchers assessed neutralizing antibody responses before and after severe acute respiratory syndrome coronavirus 2 Omicron.

5 Apr 2023

Drug used to treat liver disease may decrease SARS-CoV-2 infections and reduce COVID-19 severity

SARS-CoV-2, the virus that causes COVID-19, attaches to a cellular receptor called angiotensin-converting enzyme 2 (ACE2), and activation of the farnesoid X receptor increases ACE2 expression.

5 Apr 2023

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

In a recent study, researchers assessed serological and mucosal immunity among three differing cohorts.

4 Apr 2023

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Researchers discover a small molecule drug candidate that could provide immediate protection against infection with SARS-CoV-2.

4 Apr 2023

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

Researchers screened the circulating B lymphocyte repertoires of coronavirus disease 2019 convalescents and vaccines using multiplexed antigen panels.

3 Apr 2023

COVID-19 activates endogenous retroviruses within our genome

Researchers assess the impact of SARS-CoV-2 infection on endogenous retroviruses of the LTR69 subfamily.

28 Mar 2023

Study investigates the antigenic and viral receptor-binding properties of major Omicron BA.2.75 subvariants

Researchers in the US examined the neutralization evasion and receptor affinity properties of SARS-CoV-2 Omicron BA.2.75 sub-variants.

28 Mar 2023

New study re-examines the 'obesity paradox' in chronic heart failure patients

In a recent article published in the European Heart Journal, researchers revisited the ‘obesity paradox’ in patients with chronic heart failure (HF). Intriguingly, the theory that obesity increases the risk of HF encompasses many oddities.

27 Mar 2023

New study suggests broad neutralizing antibody could provide three years of COVID protection

In a recent article published in the journal Science Translational Medicine, researchers showed that a novel, lab-engineered monoclonal antibody (mAb), adintrevimab conferred up to 50% protection against symptomatic coronavirus disease 2019 (COVID-19). Furthermore, it demonstrated this exceptional efficacy in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–naïve individuals even at titers as low as 1:30.

27 Mar 2023

Epigenome reprogramming after SARS-CoV-2 infection

Researchers performed a 3D evaluation of SARS-CoV-2 infected human cells.

27 Mar 2023

Global search for sustainable protein sources: Turning to insects, weeds, and fungi to meet rising demand

Researchers explore novel foods such as unconventional legume crops, aquatic weeds, edible fungi, and insects as sources of proteins alternative to meat.

26 Mar 2023

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

Angiotensin News and Research

Further Reading

VUMC-led trial demonstrates the inefficacy of two investigational drugs for treating severe COVID-19

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Study highlights the potential long-term neurological effects post-COVID-19

Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission

Study reviews the diagnosis and treatment of acute myocarditis

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

The association between neutralizing antibody response breadth and long COVID symptoms

Drug used to treat liver disease may decrease SARS-CoV-2 infections and reduce COVID-19 severity

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Study identifies ultra-broad SARS-CoV-2 neutralizing antibodies that target various spike epitopes

COVID-19 activates endogenous retroviruses within our genome

Study investigates the antigenic and viral receptor-binding properties of major Omicron BA.2.75 subvariants

New study re-examines the 'obesity paradox' in chronic heart failure patients

New study suggests broad neutralizing antibody could provide three years of COVID protection

Epigenome reprogramming after SARS-CoV-2 infection

Global search for sustainable protein sources: Turning to insects, weeds, and fungi to meet rising demand

Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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