Angiotensin Converting Enzyme 2 News and Research

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Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

A new study investigates whether SARS-CoV-2 can enter and replicate in macrophages and whether ACE2 is involved in these mechanisms.

4 May 2023

Neurological phenotypes induced by SARS-CoV-2 spike protein in neurons

Researchers explored the association between SARS-CoV-2 spike protein and burst activities in neurons.

27 Apr 2023

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Researchers explored the protective systemic and mucosal immunity provided by a single dose of a live-attenuated SARS-CoV-2 vaccine candidate.

20 Apr 2023

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Research explains how the SARS-CoV-2 virus spreads efficiently by directly infecting neighboring cells through a process called cell-to-cell transmission. The virus uses a protein called occludin (OCLN) to enter the cells and causes syncytium formation, which leads to viral spread.

20 Apr 2023

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Researchers investigated the tropism of SC2r-CoVs infecting Rhinolophus bats.

18 Apr 2023

Is there an association between COVID-19 and the risk of developing an autoimmune disease?

Researchers reviewed data on the incidence of autoimmune diseases in the post-acute coronavirus disease 2019 period.

17 Apr 2023

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Researchers developed a novel intranasal vaccine candidate for coronavirus disease 2019 (COVID-19).

14 Apr 2023

The virological characteristics of XBB.1.16

Researchers perform extensive multiscale investigations to explore virological characteristics of the SARS-CoV-2 Omicron XBB subvariant, XBB.1.16.

12 Apr 2023

VUMC-led trial demonstrates the inefficacy of two investigational drugs for treating severe COVID-19

Despite the success of vaccines for preventing COVID-19, and of drugs for treating the disease, outcomes for severely ill patients admitted to the hospital remains poor.

11 Apr 2023

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Researchers found antibodies that neutralize all current SARS-CoV-2 variants.

11 Apr 2023

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Researchers assess the efficacy of the human surfactant protein A against SARS-CoV-2 infectivity.

10 Apr 2023

Study highlights the potential long-term neurological effects post-COVID-19

Researchers studied the presence of the SARS-CoV-2 spike protein in the skull-meninges-brain (SMB) axis.

10 Apr 2023

Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission

A study investigating risk factors and vectors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) household transmission reveals that the presence of the virus on the hands of primary and secondary cases and on frequently-touched surfaces is associated with transmission risk. The study is published in the journal THE LANCET Microbe.

9 Apr 2023

Angiotensin Converting Enzyme 2 News and Research

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

Neurological phenotypes induced by SARS-CoV-2 spike protein in neurons

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Protein OCLN found to play crucial role in SARS-CoV-2 cell-to-cell transmission

Unravelling the factors influencing host tropism of SARS-CoV-2-related bat coronaviruses

Is there an association between COVID-19 and the risk of developing an autoimmune disease?

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

The virological characteristics of XBB.1.16

VUMC-led trial demonstrates the inefficacy of two investigational drugs for treating severe COVID-19

Scientists isolate two antibodies that neutralize all current SARS-CoV-2 variants of concern

Study finds human surfactant protein A can inhibit SARS-CoV-2 infectivity

Study highlights the potential long-term neurological effects post-COVID-19

Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Omicron BA.5 variant demonstrates increased neuroinvasiveness and pathogenicity in mice

The association between neutralizing antibody response breadth and long COVID symptoms

Drug used to treat liver disease may decrease SARS-CoV-2 infections and reduce COVID-19 severity

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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