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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.
Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced positive topline safety and tolerability results from a Phase 1b clinical trial of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent Clostridium difficile (C. difficile) infection, antibiotic-associated diarrhea and secondary antibiotic-resistant infections in patients receiving intravenous (IV) beta-lactam antibiotic therapy. [More]
IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

The alarming increase of antibiotic-resistant bacteria poses health and economic threats worldwide, with more than 2 million Americans infected by the bacteria each year. Now, a team of Indiana University chemists and biologists has been awarded a major grant to develop and use a chemical tagging method to better understand how bacteria build their cell wall, which is still the best target for new antibiotics. [More]
Risks and benefits of fecal microbiota transplant

Risks and benefits of fecal microbiota transplant

A woman successfully treated for a recurrent Clostridium difficile infection with stool from an overweight donor rapidly gained weight herself afterwards, becoming obese, according to a case report published in the new journal Open Forum Infectious Diseases. [More]
Investigators develop microbiome map of New York City subway system

Investigators develop microbiome map of New York City subway system

The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs -- and even DNA fragments associated with anthrax and Bubonic plague -- according to a citywide microbiome map published today by Weill Cornell Medical College investigators. [More]
Researchers assess causes of febrile illnesses in Tanzanian children

Researchers assess causes of febrile illnesses in Tanzanian children

Valérie D'Acremont led the research team from the Swiss Tropical and Public Health Institute in Basel and the Policlinique Médicale Universitaire in Lausanne, who systematically assessed the causes of febrile illnesses in Tanzanian children. According to the published paper, in most cases a treatment with antimalarials or antibiotics is not required. [More]
Study: Lyme disease costs the U.S. health care system up to $1.3 billion a year

Study: Lyme disease costs the U.S. health care system up to $1.3 billion a year

Lyme disease, transmitted by a bite from a tick infected by the Borrelia burgdorferi bacteria, had long been considered easy to treat, usually requiring a single doctor's visit and a few weeks of antibiotics for most people. [More]
Study: 45% of RTI patients inappropriately prescribed antibiotics in outpatient settings

Study: 45% of RTI patients inappropriately prescribed antibiotics in outpatient settings

A new study found 45 percent of patients with respiratory tract infections (RTIs) were inappropriately prescribed antibiotics in an outpatient practice of general internal medicine and family medicine. [More]
COMBACTE-MAGNET project launched to study new treatment options for infections caused by MDR-GNB

COMBACTE-MAGNET project launched to study new treatment options for infections caused by MDR-GNB

Today 33 European academic partners and 5 pharmaceutical companies are launching a new project, COMBACTE-MAGNET, under the IMI antimicrobial resistance research programme New Drugs 4 Bad Bugs (ND4BB). [More]
Trust for America's Health supports President's proposal to end sequestration

Trust for America's Health supports President's proposal to end sequestration

The following is a statement from Jeffrey Levi, PhD, executive director of the Trust for America's Health (TFAH) and chair of the Advisory Group on Prevention, Health Promotion, and Integrative and Public Health. [More]
PPDC awards grants to three companies developing new medical devices for children

PPDC awards grants to three companies developing new medical devices for children

The Philadelphia Pediatric Medical Device Consortium announces its first three awards to companies developing new medical devices for children. [More]
Theravance Biopharma, Mylan partner to develop and commercialize TD-4208 for COPD treatment

Theravance Biopharma, Mylan partner to develop and commercialize TD-4208 for COPD treatment

Theravance Biopharma, Inc. and Mylan Inc. today announced that the two companies will partner on the development and, subject to FDA approval, commercialization of TD-4208, a novel investigational once-daily nebulized long-acting muscarinic antagonist (LAMA) for chronic obstructive pulmonary disease (COPD) and other respiratory diseases. [More]
TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Antibiotic-resistant infections are on the rise, foiling efforts to reduce death rates in developing countries where uncontrolled use of antibiotics and poor sanitation run amok. The epidemic of "superbugs," bacteria resistant to antibiotics, knows no borders -- presenting a clear and present danger around the globe. [More]
Synthetic compound shows antibiotic action against MRSA

Synthetic compound shows antibiotic action against MRSA

Microbiologists and chemists at the University of South Florida have developed and patented a synthetic compound that has shown antibiotic action against methicillin resistant Staphylococcus aureus, also known as MRSA, which can cause many serious infections and deaths. [More]
Manchester researcher discover novel way to eradicate cancer stem cells

Manchester researcher discover novel way to eradicate cancer stem cells

A way to eradicate cancer stem cells, using the side-effects of commonly used antibiotics, has been discovered by a University of Manchester researcher following a conversation with his young daughter. [More]
Antibiotic use by travellers may promote spread of drug-resistant 'super-bacteria'

Antibiotic use by travellers may promote spread of drug-resistant 'super-bacteria'

Treating travellers' diarrhoea with antibiotics can promote the spread of drug-resistant "super-bacteria". [More]
SLU researcher discovers new information about how antibiotics stop staph infections

SLU researcher discovers new information about how antibiotics stop staph infections

In research published in Proceedings of the National Academy of Sciences, assistant professor of biochemistry and molecular biology at Saint Louis University Mee-Ngan F. Yap, Ph.D., discovered new information about how antibiotics like azithromycin stop staph infections, and why staph sometimes becomes resistant to drugs. [More]
Taking antibiotics for diarrhea may put travelers at increased risk for contracting superbugs

Taking antibiotics for diarrhea may put travelers at increased risk for contracting superbugs

Taking antibiotics for diarrhea may put travelers visiting developing parts of the world at higher risk for contracting superbugs and spreading these daunting drug-resistant bacteria to their home countries, according to a new study published in Clinical Infectious Diseases and now available online. [More]
Study suggests that common gut microbe may control risk of developing MS

Study suggests that common gut microbe may control risk of developing MS

A common gut microbe might curb the risk of developing multiple sclerosis--at least in women--suggests the largest study of its kind published online in the Journal of Neurology Neurosurgery & Psychiatry. [More]
Study suggests that antibiotics may help fight norovirus

Study suggests that antibiotics may help fight norovirus

Antibiotics aren't supposed to be effective against viruses. But new evidence in mice suggests antibiotics may help fight norovirus, a highly contagious gastrointestinal virus, report scientists at Washington University School of Medicine in St. Louis. [More]
Antibiotic resistance remains a serious health problem in Australia, warns NPS MedicineWise

Antibiotic resistance remains a serious health problem in Australia, warns NPS MedicineWise

In light of a major breakthrough in the quest to find new antibiotics with the discovery of teixobactin, NPS MedicineWise warns that antibiotic resistance in Australia remains a serious health problem we all need to work to address. [More]