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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.
Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers develop computer model to reveal how antibiotic-resistant microbes develop and spread

Researchers from the Scientific Research Institute of Physical-Chemical Medicine, MIPT, the company M&S Decisions and the research department of Yandex have built a computer model of the interaction between different bacteria, and between bacteria and the gut wall. [More]
Researchers highlight how BSI infecting pathogens become more resilient

Researchers highlight how BSI infecting pathogens become more resilient

A recently published special issue of Virulence, "Bloodstream Infections", focuses on the resilience of bloodstream infections (BSI) and is endorsed by the European Study Group for Infections in Compromised Hosts of the European Society of Clinical Microbiology and Infectious Diseases. [More]
Michigan researchers use 'kidney on a chip' device to measure effect of drug doses on kidney cells

Michigan researchers use 'kidney on a chip' device to measure effect of drug doses on kidney cells

University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells. [More]
Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

An estimated 30 percent of outpatient oral antibiotic prescriptions in the U.S. in 2010-2011 may have been inappropriate, findings that support the need for establishing a goal for outpatient antibiotic stewardship, according to a study appearing in the May 3 issue of JAMA. [More]
Scientists identify novel way of synthesising promising new antibiotic

Scientists identify novel way of synthesising promising new antibiotic

A novel way of synthesising a promising new antibiotic has been identified by scientists at the University of Bristol. By expressing the genes involved in the production of pleuromutilin in a different type of fungus, the researchers were able to increase production by more than 2,000 per cent. [More]
Antibiotic treatment may allow bad bugs to flourish

Antibiotic treatment may allow bad bugs to flourish

Antibiotics are essential for fighting bacterial infection, but, paradoxically, they can also make the body more prone to infection and diarrhea. [More]
Promising method may help identify new antimicrobials to target CRE infection

Promising method may help identify new antimicrobials to target CRE infection

In recent years, hospitals have reported dramatic increases in the number of cases of the highly contagious, difficult-to-treat, and often deadly antibiotic-resistant bacteria carbapenem-resistant Enterobacteriaceae (CRE). Now, investigators at Beth Israel Deaconess Medical Center have developed a promising method of identifying new antimicrobials that target these organisms. The research is published in April issue of the journal ASSAY and Drug Development Technologies. [More]
Gut bacteria linked to risk of bloodstream infections after chemotherapy

Gut bacteria linked to risk of bloodstream infections after chemotherapy

A new study led by researchers at the University of Minnesota and Nantes University Hospital in France shows that the bacteria in people's gut may predict their risk of life-threatening blood infections following high-dose chemotherapy. [More]
Existing non-antibiotic therapeutic drugs could help combat antibiotic-resistant pathogens

Existing non-antibiotic therapeutic drugs could help combat antibiotic-resistant pathogens

The rise of antibiotic resistant bacterial pathogens is an increasingly global threat to public health. In the United States alone antibiotic resistant bacterial pathogens kill thousands every year. [More]
Study shows canine AD shares significant features of human version

Study shows canine AD shares significant features of human version

Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical estimates also show that approximately 10 percent of dogs have atopic dermatitis. [More]
Borrelia infection can cause scleratrophic skin lesions in certain countries

Borrelia infection can cause scleratrophic skin lesions in certain countries

This review summarizes the literature on scleratrophic skin lesions as a manifestation of a Borrelia infection. An association of morphea with Lyme borreliosis LB was mainly reported from Middle-European Countries, Japan and South America. B. afzelii has been identified predominantly from the chronic skin lesions of acrodermatitis chronica atrophicans (ACA) and has been cultivated from morphea lesions in isolated cases. [More]
New photo-switchable molecule for PDT could help treat rapidly growing tumors

New photo-switchable molecule for PDT could help treat rapidly growing tumors

Photoswitchable agents might reduce side effects of a chemotherapy. So far, photodynamic therapies have been dependent on oxygen in the tissue. But hardly any oxygen exists in malignant, rapidly growing tumors. [More]
BGU researchers develop innovative anti-biofilm coating for medical, industrial applications

BGU researchers develop innovative anti-biofilm coating for medical, industrial applications

Researchers at Ben-Gurion University of the Negev have developed an innovative anti-biofilm coating, which has significant anti-adhesive potential for a variety of medical and industrial applications. [More]
Immunology experts aim to develop point-of-care test for early detection of Lyme disease

Immunology experts aim to develop point-of-care test for early detection of Lyme disease

As part of the EU "ID Lyme" project, the infection immunology working group at the Institute for Hygiene and Applied Immunology at the Center for Pathophysiology, Infectiology and Immunology at the Medical University of Vienna is working on developing of a new test for early detection of Lyme disease (borreliosis). [More]
Researchers determine 3-D structure of RlmN protein from bacteria

Researchers determine 3-D structure of RlmN protein from bacteria

The structure of a bacterial RNA-binding protein has been determined in the act of modifying a molecule of RNA -- an achievement that provides researchers with a unique view of the protein's function in action and could lead to clues that would help in the fight against the development of antibiotic-resistant infections. [More]
Scientists map core genes involved during DNA uptake in strep bacteria

Scientists map core genes involved during DNA uptake in strep bacteria

Bacteria possess the ability to take up DNA from their environment, a skill that enables them to acquire new genes for antibiotic resistance or to escape the immune response. Scientists have now mapped the core set of genes that are consistently controlled during DNA uptake in strep bacteria, and they hope the finding will allow them to cut off the microbes' ability to survive what doctors and nature can throw at them. [More]
NPS MedicineWise reminds Australians to prevent overuse and misuse of antibiotics

NPS MedicineWise reminds Australians to prevent overuse and misuse of antibiotics

Following from last night’s Catalyst episode, ‘Antibiotic Resistance’ on ABC TV examining Australia’s profligate use of antibiotics, NPS MedicineWise is reminding Australians to preserve the miracle of antibiotics by avoiding antibiotics when they’re not needed. [More]
Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

Scientists evaluate phage-based therapy to battle antibiotic-resistant bacterial superbug infections

Flinders University scientists are looking to bacteriophages – highly specific viruses - as the as the best way to attack antibiotic-resistant bacterial superbug infections. [More]
Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Researchers develop new mathematical model to evaluate best treatment protocol to clear infection

Antibiotic resistance is one of the most challenging problems in modern medicine. A new study by Erida Gjini and Patricia H. Brito from the Instituto Gulbenkian de Ciência, provides a new mathematical model to evaluate the best treatment protocol to clear an infection, by taking into account the role of the host immune system. [More]

Researchers focus on novel target to treat bacterial infection

Bacterial infection takes hold in the body when a pathogenic microorganism delivers toxins to healthy cells. One way bacteria accomplish this is by releasing vesicles, which act as tiny envelopes transporting toxins and other virulence factors to host cells. These toxins allow the bacteria to "make themselves at home" in cells. [More]
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