Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Food for thought: South European Atlantic diet shows promising link to lower depression risk

Researchers evaluate the effects of the Southern European Atlantic Diet on depression.

27 Jun 2023

World-renowned researcher receives top award for contributions to clinical psychopharmacology

Dennis Charney, MD, the Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai and President for Academic Affairs of the Mount Sinai Health System, has received the prestigious Donald Klein Lifetime Achievement Award from the American Society for Clinical Psychopharmacology (ASCP).

26 Jun 2023

Study links poor sense of smell with increased risk of depression in older adults

In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers at Johns Hopkins Medicine say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.

26 Jun 2023

Antidepressant prescriptions may reduce the risk of testing positive for COVID-19

New research led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has found that community mental health patients who were prescribed antidepressants were significantly less likely to test positive for COVID-19 when admitted to inpatient care.

20 Jun 2023

Common laxative prucalopride may be useful as a pro-cognitive treatment in psychiatric conditions

Cognitive deficits accompany mood disorders and other psychiatric conditions, often with debilitating effects.

13 Jun 2023

Leucine deficient diet has antidepressant effects on chronic restraint stress-induced depression-like behaviors

Depression is a leading cause of disability around the world and contributes greatly to the global burden of disease.

6 Jun 2023

Is having a new child associated with increased antidepressant treatment in men?

Study determines whether recent fatherhood was associated with increased antidepressant treatment.

2 Jun 2023

Research finds more depressed patients with activated immune systems than previously estimated

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has used an assessment of gene expression involved in the immune response to show that there could be more patients with MDD with activated immune systems than research has previously estimated.

30 May 2023

Study reports a shared genetic basis for cannabis use and psychiatric disorders

A new study from the University of Oslo published in the Lancet Psychiatry, reported a shared genetic basis for cannabis use and psychiatric disorders, including schizophrenia and bipolar disorder.

19 May 2023

Neuropathic pain study uncovers pathophysiological mechanism and promising therapeutic target

Neuropathic pain -; abnormal hypersensitivity to stimuli -; is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV.

5 May 2023

The association between breastfeeding, drug exposure, and infant outcomes: more research is needed

Researchers explored the data linking breastfeeding, infant outcomes, and drug exposure.

28 Apr 2023

Pain, hope, and science collide as athletes turn to magic mushrooms

The boxer felt broken. Every day, he was waking up in pain. Some days, it was debilitating headaches. Other times, it was his back. Or his fists. His ribs. His nose. On top of that, he had mood swings. Depression. Anxiety.

24 Apr 2023

Study sheds light on the mechanisms of brain plasticity induced by fluoxetine

A recent study, published in Neuropsychopharmacology, conducted by researchers from the University of Helsinki and the University of Eastern Finland, sheds light on the mechanisms of neural plasticity induced by the antidepressant fluoxetine.

5 Apr 2023

The intercommunication between the central nervous system and the digestive system and its contribution to mental health status

Researchers presented a comprehensive analysis of the correlation between gut microbiota and neurological as well as psychiatric disorders.

3 Apr 2023

Gut microbiomes and mental health: how do they interact?

A new study published in the journal Frontiers in Medicine reviewed recent literature on the link between gut microbiota, the brain, and neurological disorders.

19 Mar 2023

Smoking cessation drug may help people stop using cocaine while in treatment for OUD

For some people receiving methadone for treatment of opioid use disorder (OUD), the co-use of opioids and stimulants such as cocaine is an issue.

15 Mar 2023

Rapid shift to virtual behavioral health care during the pandemic helped adhere to depression treatment

The rapid transition from in-person to care to telemedicine visits at the start of the COVID‑19 pandemic did not adversely affect the quality of care – and even improved some aspects of care – for patients with major depression in a major integrated health system, according to a new report.

10 Mar 2023

Augmenting an antidepressant with aripiprazole may help some older adults with treatment-resistant depression

For older adults with clinical depression that has not responded to standard treatments, adding the drug aripiprazole (brand name Abilify) to an antidepressant they're already taking is more effective than switching from one antidepressant to another, according to a new multicenter study led by Washington University School of Medicine in St. Louis.

3 Mar 2023

Leucine deprivation results in antidepressant effects, study shows