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A strategic collaboration to speed up the development of allogeneic cell therapies

The University of Texas MD Anderson Cancer Center and Allogene Therapeutics, Inc. today announced a strategic five-year collaboration agreement for the preclinical and clinical investigation of AlloCAR T candidates across Allogene's broad portfolio of hematologic and solid tumors.

16 Oct 2020

Sanofi Translate Bio MRT5500 COVID-19 vaccine shows promise in preclinical trials

The COVID-19 pandemic is threatening to come back in greater intensity during the winter and fall. Faced with this threat, vaccine development efforts are entering a phase of renewed focus, attempting to identify antigens capable of eliciting protective levels of neutralizing antibodies. A new study published on the preprint server bioRxiv* in October 2020 reports on a novel mRNA vaccine candidate's performance in two animal models.

16 Oct 2020

Rapid SARS‐CoV‐2 IgM‐IgG combined antibody test

A recent study published on the preprint server medRxiv in October 2020 reports a new diagnostic test for SARS-CoV-2 based on the detection of antibodies.

15 Oct 2020

Certain live-attenuated vaccines can prevent severe complications of COVID-19

COVID-19 continues to wreak havoc globally, with over one million deaths to date. Yet what if an existing vaccine could make COVID-19 less deadly? A study just published put the theory to test, with promising results.

15 Oct 2020

Army researchers team up to test alternative ways to measure COVID-19 antibody levels

Researchers with the U.S. Army Futures Command are part of a team that tested alternative ways to measure COVID-19 antibody levels, resulting in a process that is faster, easier and less expensive to use on a large scale.

14 Oct 2020

Research identifies antigen-specific peripheral T follicular helper cells in COVID-19 infected patients

Researchers have found peripheral T follicular helper cell responses to different structural proteins of SARS-CoV-2 and have studied how the response occurs over time.

14 Oct 2020

SARS-CoV-2 infection of carotid arteries may explain vascular involvement in COVID-19

A new study published on the preprint server bioRxiv in October 2020 shows that the virus causing COVID-19, namely, SARS-CoV-2, produces replicative infection in the carotid arteries and affects the vascular responses. This could have a profound bearing on the understanding of the disease and its clinical treatment.

14 Oct 2020

Children and teens can spread SARS-CoV-2 in their households

A team of researchers from the Georgia Department of Public Health and the U.S Centers for Disease Control and Prevention (CDC) aimed to determine the secondary attack rates (SAR) among household contacts of children and adolescents who contracted SARS-CoV-2 during an outbreak at an overnight camp in June.

13 Oct 2020

Cancer-killing T cells release chemicals to direct swarms towards tumors

When immune system T cells find and recognise a target, they release chemicals to attract more T cells which then swarm to help subdue the threat, shows a new study published today in eLife.

13 Oct 2020

Mothers transmit passive protection against SARS-CoV-2 to their newborns

A recent study published on the preprint server medRxiv in October 2020 shows that newborns may be protected from acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by antibodies in the mother’s blood that travels through the placenta.

13 Oct 2020

CAR NKT cells offer a promising approach to combat hard-to-treat solid tumors

Natural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have been developed into a novel form of immunotherapy to treat patients with cancer.

13 Oct 2020

COVID-19 vaccine candidate shows potent immune response

A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer shows potent preclinical immune responses -; including several that distinguish it from other COVID-19 vaccine approaches -; according to a preprint deposited in the BioRxiv repository this week.

13 Oct 2020

Why blood type O might lower risk for SARS-CoV-2 infection

The author hypothesizes that people with non-O blood groups may have highest contact with the SARS-CoV-2 virus via the formation of in intermediate structure, resulting in possibly higher infection rates and more severe symptoms.

12 Oct 2020

Scientists develop new type of precise therapeutic vaccine against leukemia

Exploration of new leukemia antigens and construction of appropriate delivery systems using FDA-approved material are important strategies for developing leukemia vaccines for clinic use.

12 Oct 2020

A new therapeutic approach for Epstein-Barr virus-associated tumors

A research team at LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that exosomes derived from Vδ2-T cells (Vδ2-T-Exos) can effectively control Epstein-Barr virus-associated tumours and induce T-cell anti-tumour immunity.

12 Oct 2020

Temporal predictors of SARS-CoV-2 antibodies

Researchers in a recent paper published as a preprint on the preprint medRxiv, study the clinical factors, the laboratory assays to streamline plasma donor selection, and the durability of nAb responses in adults.

11 Oct 2020

New study reports on extremely potent human monoclonal antibodies for SARS-CoV-2

Researchers have recovered and identified the various types of neutralizing antibodies for SARS-CoV-2 from convalescent COVID-19 patients. Of these, they identified three that are extremely potent and could be used to develop treatment therapies.

11 Oct 2020

Exciting findings on CD8 T cell response in recovered COVID patients

An international team of scientists has identified novel T cell-recognized epitopes spanning different proteins of severe acute respiratory syndrome coronavirus 2 in COVID-19 recovered patients. The scientists have also revealed phenotypical characteristics of the T cell population.

11 Oct 2020

Serum antibodies from SARS-CoV patients effectively neutralized SARS-CoV-2 in cultured cells

Antibodies in serum samples collected from patients infected with SARS-CoV during the 2003 outbreak effectively neutralized SARS-CoV-2 infection in cultured cells, according to a new study.

9 Oct 2020

Researchers develop hand-held device to measure cancer biomarker

Researchers at McMaster and Brock universities have created the prototype for a hand-held device to measure a biomarker for cancer, paving the way for home-based cancer monitoring and to improve access to diagnostic testing.

9 Oct 2020