Antigen News and Research

RSS

Obese men may have elevated risk of biochemical recurrence after radical prostatectomy

Among men with prostate cancer who underwent radical prostatectomy (RP), those who were obese had a higher risk of biochemical recurrence, according to data presented at the American Association for Cancer Research Special Conference Obesity and Cancer: Mechanisms Underlying Etiology and Outcomes, held Jan. 27-30.

27 Jan 2018

UTokyo enters into agreement for developing personalized cancer vaccine

The University of Tokyo entered an agreement for developing a personalized cancer vaccine using a novel method involving the body's immune response.

25 Jan 2018

Researchers report racial and ethnic differences in live donor kidney transplants

Despite efforts over the past two decades to increase the number of black and Hispanic patients receiving kidney transplants from related or unrelated living donors, these racial/ethnic minority patients are still much less likely to undergo such transplants than white patients, Johns Hopkins researchers report.

24 Jan 2018

Anti-inflammatory pill could help make vaccines more effective for the elderly

By identifying why skin immunity declines in old age, a UCL-led research team has found that an anti-inflammatory pill could help make vaccines more effective for elderly people.

22 Jan 2018

Novel gene expression analysis technique can accurately and quickly measure RNA

A University of Illinois and Mayo collaboration has demonstrated a novel gene expression analysis technique that can accurately measure levels of RNA quickly and directly from a cancerous tissue sample while preserving the spatial information across the tissue --something that conventional methods cannot do.

18 Jan 2018

Genetic study identifies six new gene regions associated with type 1 diabetes in children

This article outlines a recent study which identified six novel gene regions in children who are at risk of type 1 diabetes.

17 Jan 2018

Scientists identify six new gene regions that may help treat type 1 diabetes

Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating or even preventing it.

17 Jan 2018

Researchers use immune-mimicking biomaterial scaffolds to fast track T cell therapies

Immunologists and oncologists are harnessing the body's immune system to fight cancers and other diseases with adoptive cell transfer techniques. In a normal immune response, a type of white blood cell known as T cells are instructed by another kind of immune cell called an antigen-presenting cell (APC) to expand their numbers and stay alive.

15 Jan 2018

Researchers develop remote-controlled mechanogenetics system to target and kill cancer cells

A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells.

15 Jan 2018

Novel polygenic hazard score captures age variations of aggressive prostate cancer

An international team, led by researchers at the University of California San Diego School of Medicine, has developed and validated a genetic tool for predicting age of onset of aggressive prostate cancer, a disease that kills more than 26,000 American men annually.

12 Jan 2018

Deciphering Antibodies with Next-Generation Protein Sequencing Technology

Mr. Mingjie Xie, MSc, MBA, is the co-founder and CEO of Rapid Novor Inc. He is a computer scientist by training andreceived his MSc degree from Western University in the field of bioinformatics. He received his MBA degree from Richard Ivey School of Business to pursue his interests in business. Prior to co-founding Rapid Novor Inc, Mingjie is the COO of a bioinformatics software company.

From Rapid Novor Inc 9 Jan 2018

Scientists use artificial intelligence to create new ‘ImmunoMap’

Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical "antennas" on the surface of immune system T-cells.

8 Jan 2018

Gene therapy with CAR T-cells could create long-term immunity from HIV

Through gene therapy, researchers engineered blood-forming stem cells (hematopoietic stem/progenitor cells, or HSPCs) to carry chimeric antigen receptor (CAR) genes to make cells that can detect and destroy HIV-infected cells.

29 Dec 2017

New method sifts through millions of molecular targets to find precise tumor beacon

By screening millions of molecular targets, researchers have uncovered a tumor beacon detected by the immune cells of two patients with colorectal cancer.

22 Dec 2017

Clinical benefit of new cancer therapies may justify the expensive price

Researchers from the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, selected to estimate the cost-effectiveness of the newly approved CAR-T therapies, have found the clinical benefit may justify the expensive price.

20 Dec 2017

Research uncovers mechanism implicated in defective function of tumor-associated dendritic cells

A new study from The Wistar Institute revealed the mechanism implicated in the defective function of tumor-associated dendritic cells (DCs), a specialized type of immune cells that expose the antigens on their surface to activate the T cells.

15 Dec 2017

Cancer immunotherapy’s effectiveness may depend on patient’s genetic makeup

Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.

15 Dec 2017

Study: Living Lyme disease bacteria found months after antibiotic treatment

Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the US, today announced results of two papers published in the peer-reviewed journals PLOS ONE and American Journal of Pathology, that seem to support claims of lingering symptoms reported by many patients who have already received antibiotic treatment for the disease.

14 Dec 2017

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA specifically to cancer cells.

13 Dec 2017

Cellular self-digestion process plays role in development of autoimmune diseases

Autophagy allows cells to degrade and recycle their cellular components. Researchers at UZH have now demonstrated that the autophagy machinery in certain immune cells leads to the immune system attacking the central nervous system.