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Scientists develop software that predicts leukemia-specific immune targets

University of North Carolina Lineberger Comprehensive Cancer Center scientists have developed a software program that can accurately predict which tumor-specific markers will show up on the surface of leukemia cells in patients who have received stem cell transplants.

11 Dec 2017

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

In a pair of clinical trials stretching from Philadelphia to Tokyo, the chimeric antigen receptor (CAR) T cell therapy Kymriah (formerly known as CTL019) demonstrated long-lasting remissions in non-Hodgkin's lymphoma (NHL) patients.

11 Dec 2017

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Results from a phase 2 clinical trial, presented by Seattle Children's Research Institute at the 59th American Society of Hematology Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.

11 Dec 2017

Two immunotherapy approaches for multiple myeloma show hope

Researchers from the University of Pennsylvania's Abramson Cancer Center have developed two experimental immunotherapy methods that include one chimeric antigen receptor (CAR) T cell therapy for the treatment of multiple myeloma patients who were not responding to other treatments.

11 Dec 2017

Researchers seek to understand role of novel protein in tumor metastasis

Metastasis, the process in which a tumor spreads to other parts of the body, is responsible for 90% of deaths from tumors. It is the greatest challenge to a cancer patient's survival. Metastatic spread occurs in several steps, these include that tumor cells become mobile and cross into and out of blood vessels.

8 Dec 2017

Researchers identify risk factor for drug-induced skin disease in diabetic patients

Researchers have identified a type of human leukocyte antigen (HLA) that is associated with the skin disease bullous pemphigoid (BP) in diabetic patients administered with DPP-4 inhibitory drugs.

6 Dec 2017

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

For prostate cancer patients who have rising levels of PSA (a cancer indicator) even after radical prostatectomy, early treatment makes a difference.

5 Dec 2017

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Children with an extremely deadly form of brain cancer might benefit from a new treatment that aims to direct an immune response against an abnormally shaped protein found exclusively on cancer cells, according to a new study led by UC San Francisco researchers.

4 Dec 2017

Scientists use computer analysis to complete antibody blueprint

Antibodies defend our bodies against intruders. These molecules consist of proteins with attached sugars. However, the blueprint directing the processing of these sugars on the protein was not well understood until now.

30 Nov 2017

New vaccine technique can effectively combat breast cancer, mice study shows

A new vaccine technique can fight a certain type of breast cancer in mice. So-called HER2-positive breast cancer accounts for between 20 and 30 per cent of all cases of breast cancer in humans.

30 Nov 2017

Study unveils new immunotherapeutic target against multiple myeloma

Osaka - In recent decades monoclonal antibody-based treatment of cancer has been established as one of the most successful therapeutic strategies for both solid tumors and blood cancers.

27 Nov 2017

UNC Lineberger professor receives The Leukemia & Lymphoma Society grant for immunotherapy research

UNC Lineberger Comprehensive Cancer Center researcher Barbara Savoldo, MD, PhD, was awarded a $600,000, three-year grant from The Leukemia & Lymphoma Society to support research into an immunotherapy treatment being developed with a "safety switch" to safeguard against potential side effects of the treatment.

21 Nov 2017

Use of Prostate Health Index cuts down need for uncomfortable biopsies

The Prostate Health Index is a cost-effective tool used by urologists to detect prostate cancer. It reduces the risk of over diagnosis, and cuts down on the need to send men for unnecessary and often uncomfortable biopsies.

20 Nov 2017

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate to all those different cell fates.

15 Nov 2017

Study identifies novel mechanism by which tumors can resist cancer immunotherapy

A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy.

10 Nov 2017

Texas Biomedical Research Institute tests promising new treatment for HBV infection

Research at the Southwest National Primate Research Center on the campus of Texas Biomedical Research Institute helped advance a new treatment now in human trials for chronic hepatitis B virus (HBV) infection.

7 Nov 2017

Collaborative research identifies broadly cross-protective vaccines for H3N2 influenza

A collaborative research and development partnership between researchers at the University of Georgia and Sanofi Pasteur, the largest influenza vaccine manufacturer in the world, has resulted in the identification of a vaccine candidate that protects against multiple co-circulating strains of H3N2 influenza isolated over five seasons following testing in mouse and ferret models.

2 Nov 2017

Gut bacteria can influence how cancer responds to immunotherapy

Bacteria that live in the human digestive tract can influence how cancer responds to immunotherapy, opening a new avenue for research to improve treatment, a team led by researchers at The University of Texas MD Anderson Cancer Center reports in the journal Science.

2 Nov 2017

Researchers develop new, three-step system to eliminate colorectal cancer

Researchers at Memorial Sloan Kettering Cancer Center in New York City and Massachusetts Institute of Technology in Boston have developed a new, three-step system that uses nuclear medicine to target and eliminate colorectal cancer.

2 Nov 2017

Common factors that could change your PSA test results

Most men in their 50s, who face an increasing risk of prostate cancer as they age, are familiar with the common screening exam known as the prostate specific antigen (PSA) test. But many are less familiar with how the test works and why different factors, such as prescription medications and infections, can influence the test results.

28 Oct 2017

Antigen News and Research

Scientists develop software that predicts leukemia-specific immune targets

CAR T cell therapy shows long-lasting remissions in non-Hodgkin's lymphoma patients

Drug improves disease-free, overall survival after hematopoietic stem cell transplants

Two immunotherapy approaches for multiple myeloma show hope

Researchers seek to understand role of novel protein in tumor metastasis

Researchers identify risk factor for drug-induced skin disease in diabetic patients

PET scans can predict prostate cancer patients’ response to salvage radiation treatment

New treatment aims to target abnormally shaped protein in deadly childhood brain cancer

Scientists use computer analysis to complete antibody blueprint

New vaccine technique can effectively combat breast cancer, mice study shows

Study unveils new immunotherapeutic target against multiple myeloma

UNC Lineberger professor receives The Leukemia & Lymphoma Society grant for immunotherapy research

Use of Prostate Health Index cuts down need for uncomfortable biopsies

Scientists find key that allows neural differentiation of microRNA-deficient pluripotent stem cells

Study identifies novel mechanism by which tumors can resist cancer immunotherapy

Texas Biomedical Research Institute tests promising new treatment for HBV infection

Collaborative research identifies broadly cross-protective vaccines for H3N2 influenza

Gut bacteria can influence how cancer responds to immunotherapy

Researchers develop new, three-step system to eliminate colorectal cancer

Common factors that could change your PSA test results

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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