Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.
A potentially life-saving treatment for sepsis has been under our noses for decades in the non-steroidal anti-inflammatory drugs most people have in their medicine cabinets, a new University of Colorado Boulder study suggests.
Many of us have noted how our hands and feet swell after eating too much salt. Now scientists are exploring how high salt intake can also make cells throughout the body of females swell, rupture, dump their contents and die, triggering an immune reaction that contributes to chronic high blood pressure.
Programmed cell death is an integral part of embryonic development. Exploring the regulation of the process, Ludwig-Maximilians-Universitaet in Munich researchers have shown that so-called microRNAs protect the precursors of neurons from 'precocious' elimination.
In the outpatient clinic and in the laboratory our current research studies aim at understanding the mechanisms of release and clearance and the biological functions of exosomes and membrane particles in the plasma of individuals who develop emphysema, a form of chronic obstructive pulmonary disease characterized by enlargement of airspaces and loss of alveoli.
Mycobacterium tuberculosis has been called "the perfect pathogen." These bacteria hijack human macrophages, persist inside the cells to evade immune destruction, and then prevent the macrophage from undergoing programmed cell death.
Throughout the world, many medicinal compounds are being discovered. Scientists have learnt to modify the chemical structures of active compounds so that they can improved therapeutic activity and reduced the toxicity.
Researchers have grown heart tissue by seeding a mix of human cells onto a 1-micron-resolution scaffold made with a 3-D printer.
The University Complutense of Madrid (UCM), one of the oldest Universities in the world, presents the results of its latest research confirming the irreversible damage to animals’ eyes caused by light emitted from digital screens.
Researchers from the Centre for Cancer Biology at the University of South Australia have found that a deficiency of caspase-2 enzymes place people at a higher risk of developing tumours.
Scientists from the Florida campus of The Scripps Research Institute have been awarded approximately $1.8 million from the National Institute of General Medical Sciences of the National Institutes of Health to develop a series of drug candidates for a number of diseases, including heart disease, rheumatoid arthritis and several neurodegenerative disorders.
In a study to be presented Saturday, Jan. 28, in the oral concurrent session at 8:45 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, researchers evaluated a possible regenerative patch by using human umbilical cord in two studies titled Cryopreserved Human Umbilical Cord (HUC) vs Acellular Dermal Matrix (ADM) for In-Utero Spina Bifida Repair and the study Conventional vs cryopreserved human umbilical cord (HUC) patch based on repair for in-utero spina bifida in a sheep model.
An enzyme identified in Saccharomyces cerevisiae, commonly known as brewer's or baker's yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL) cells.
The IncuCyte live-cell analysis platform from Essen BioScience has been cited in more than 1000 peer-reviewed publications since its introduction.
New research published in the Journal of Leukocyte Biology, shows that a high-fiber diet likely inhibits gout-related inflammation caused by monosodium urate (MSU) crystals.
Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body.
An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study.
AMSBIO offers an extensive range of proteins, antibodies, assays and kits covering every single target of major cellular metabolic pathways including folate metabolism, pyruvate metabolism (with and without oxygen), citrate metabolism, O2 consumption and toxicity, oxidative stress and fatty acid oxygen measurement.
One of the most significant ways in which the human brain is unique is the size and structure of the cerebral cortex. But what drives the growth of the human cortex, likely the foundation for our unique intellectual abilities?
A new active pharmaceutical ingredient may help against severe forms of testicular cancer, which only respond inadequately to other therapies.
Despite many successes in treating pediatric cancer, young children remain at high risk for developing severe, long-lasting impairments in their brain, heart, and other vital organs from chemotherapy and radiation treatments. In adults, however, these tissues are relatively spared.