Apoptosis News and Research RSS Feed - Apoptosis News and Research

Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.
Enzyme that cleaves beta carotene may control testosterone levels

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found. [More]
Study highlights requirement of protein in initiation of apoptosis in uveal melanoma

Study highlights requirement of protein in initiation of apoptosis in uveal melanoma

New research from the University of Liverpool has identified the role of a specific protein in the human body that can help prevent the survival and spread of eye cancer, by initiating cancer 'cell-suicide'. [More]
Applying quantitative microscopy to live cells

Applying quantitative microscopy to live cells

Microscopy's got a long history. It was developed about 350 years ago for scientists to visualize things they could discern, but not describe. The two pioneers of microscopy were Antoine van Leeuwenhoek, who developed the first microscope and soon after the renowned scientist, Robert Hooke. [More]
UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

UC San Diego scientists reveal surprising role for Hippo pathway in subduing tumor immunogenicity

Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings, published in Cell on December 1, could have a clinical role in improving efficiency of immunotherapy drugs. [More]
Scientists discover unique genomic changes integral to testicular cancer development

Scientists discover unique genomic changes integral to testicular cancer development

Researchers led by scientists at Dana-Farber Cancer Institute say they have identified unique genomic changes that may be integral to testicular cancer development and explain why the great majority are highly curable with chemotherapy - unlike most solid tumors. [More]
Targeting metabolic function of breast cancer may help combat disease

Targeting metabolic function of breast cancer may help combat disease

How does a cancer cell burn calories? New research from Thomas Jefferson University shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells. [More]
TMDU researchers identify novel type of cell death in Huntington's disease

TMDU researchers identify novel type of cell death in Huntington's disease

In Huntington's disease (HD), the huntingtin gene is mutated, causing progressive neuronal death. [More]
BAG3 protein plays protective role by limiting reperfusion injury to the heart

BAG3 protein plays protective role by limiting reperfusion injury to the heart

The inability of cells to eliminate damaged proteins and organelles following the blockage of a coronary artery and its subsequent re-opening with angioplasty or medications - a sequence known as ischemia/reperfusion - often results in irreparable damage to the heart muscle. [More]
International scientists unravel mystery of newly discovered type of controlled cell death

International scientists unravel mystery of newly discovered type of controlled cell death

A multidisciplinary international team of scientists solved the mystery of a recently discovered type of controlled cell death, mapping the path to potential therapies for conditions ranging from radiation injury to cancer. [More]
Scientists show how key protein can be important driver of prostate cancer

Scientists show how key protein can be important driver of prostate cancer

Scientists at The Wistar Institute have demonstrated how a protein called TRAP1 - an important regulator of energy production in healthy and cancerous cells - is an important driver of prostate cancer and appears to be a valuable therapeutic target for the disease. [More]
Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter intestinal bacteria in a manner that promotes intestinal inflammation and colorectal cancer, according to a new study. [More]
New treatment with therapeutic short interfering RNA could help thwart cancer

New treatment with therapeutic short interfering RNA could help thwart cancer

In the fight against cancer, doctors dish out combination-blows of surgery, chemotherapy and other drugs to beat back a merciless foe. Now, scientists have taken early steps toward adding a stinging punch to clinicians' repertoire. [More]
Nano-biointeraction and nanopathology

Nano-biointeraction and nanopathology

Nanoparticles enter the organism in a number of ways. In most cases through inhalation and ingestion. When inhaled, the majority of them are expelled with the next breath. When ingested, most of them are gotten rid of through feces. [More]
Researchers take significant step forward in genetic sex reprogramming research

Researchers take significant step forward in genetic sex reprogramming research

An international team of researchers, led by the University of Granada, has taken a significant step forward on the research on 'genetic sex reprogramming', which is closer now, although it's still an utopia. [More]
New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase. [More]
TSRI scientists elucidate how Zika virus attacks the brains of newborns

TSRI scientists elucidate how Zika virus attacks the brains of newborns

In a study that could one day help eliminate the tragic birth defects caused by Zika virus, scientists from the Florida campus of The Scripps Research Institute have elucidated how the virus attacks the brains of newborns, information that could accelerate the development of treatments. [More]
Johns Hopkins researchers identify protein that triggers brain cell death from strokes and injuries

Johns Hopkins researchers identify protein that triggers brain cell death from strokes and injuries

Despite their different triggers, the same molecular chain of events appears to be responsible for brain cell death from strokes, injuries and even such neurodegenerative diseases as Alzheimer's. [More]
BUSM scientists map active human apoptosome to provide better understanding of cell death

BUSM scientists map active human apoptosome to provide better understanding of cell death

Programmed cell death, or apoptosis, plays a central role in the maintenance of human health by providing a line of defense against unrestricted cell growth that occurs in many cancers and AIDS as well as in neurodegenerative diseases and stroke. [More]
Researchers reveal how ultrasmall nanoparticles can kill cancer cells

Researchers reveal how ultrasmall nanoparticles can kill cancer cells

Nanoparticles known as Cornell dots, or C dots, have shown great promise as a therapeutic tool in the detection and treatment of cancer. [More]
Scientists discover new switch that coordinates DNA repair and cell death

Scientists discover new switch that coordinates DNA repair and cell death

The genetic information of every cell is encoded in the sequence of the DNA double helix. Double strand breaks in the DNA, which can be induced by radiation, are a dangerous threat to the cells, and if not properly repaired can lead to cancer. [More]
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