Artemisinin News and Research

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Artemisinin is a drug used to treat multi-drug resistant strains of falciparum malaria. The compound (a sesquiterpene lactone) is isolated from the plant Artemisia annua. Not all plants of this species contain artemisinin.

U.N. General Assembly passes resolution urging renewed efforts to fight malaria

Ahead of World Malaria Day on April 25, the U.N. General Assembly on Monday adopted a resolution urging governments, U.N. agencies, nongovernmental organizations (NGOs), and private foundations to accelerate their efforts and build upon established successes in the fight against the disease, particularly in Africa, Deutsche Presse-Agentur/M&C reports.

20 Apr 2011

iOWH's semisynthetic ART enters production, distribution phase to combat malaria

The Institute for OneWorld Health, a non-profit drug development organization, announced today that its development of an alternative source of artemisinin using pioneering synthetic biology technology has successfully entered the production and distribution phase.

18 Apr 2011

Artemisinin or high-pressure oxygen can boost natural cancer remedy

A technique Michael Jackson reportedly used to prolong his youth is showing promise as a way to boost the effectiveness of a natural cancer remedy.

5 Apr 2011

Government of Canada commits to contribute towards global effort to combat malaria

Canada is delivering on its commitment to help the world's most vulnerable, thanks to new developments which will provide an affordable, reliable, and stable treatment for malaria that will save millions of lives, especially those of women and children in Africa.

19 Mar 2011

Anacor Pharma, MMV enter agreement to develop AN3661 for malaria treatment

Anacor Pharmaceuticals announced today that it has entered into a development agreement with Medicines for Malaria Venture to develop Anacor's compound AN3661 for the treatment of malaria.

18 Mar 2011

Anacor and iOWH establish research agreement to identify new drugs for shigellosis

Anacor Pharmaceuticals (NASDAQ:ANAC) and the Institute for OneWorld Health (iOWH) today announced the establishment of a joint research agreement to discover antibacterial compounds for treating shigellosis.

8 Mar 2011

Tropical seaweed's antifungal chemical cues may have promising antimalarial properties for humans

A group of chemical compounds used by a species of tropical seaweed to ward off fungus attacks may have promising antimalarial properties for humans. The compounds are part of a unique chemical signaling system that seaweeds use to battle enemies - and that may provide a wealth of potential new pharmaceutical compounds.

22 Feb 2011

Advocates call for follow-through on decade-old pledge to remove tariffs on malaria treatments, prophylactics in Africa

"Malaria prevention advocates say many lives can be saved by removing taxes and tariffs from essential commodities used to fight the disease," VOA News reports. A decade ago, African leaders promised to remove tariffs on products used to fight malaria, but only six countries have actually done so, according to the Malaria Taxes and Tariffs Advocacy Project, which held a meeting in Geneva on Wednesday, Reuters reports.

14 Feb 2011

NBC News examines drug-resistant malaria along Thai-Cambodian border

NBC News' "World Blog" reports on the emergence of drug-resistant malaria along the border between Thailand and Cambodia. "The Pailin area [in Cambodia] is now the epicenter of a fight to contain a growing resistance to Artemisinin, which is the world's main anti-malarial drug," the blog writes before noting the global health community's efforts to contain the spread of drug-resistant malaria.

24 Jan 2011

News outlets examine reaction to WHO plan to contain drug-resistant malaria

In follow-up coverage of the WHO's announcement Wednesday of a plan to contain the spread of artemisinin-resistant malaria, news outlets examined the scope of the problem, reactions to the plan and speculations of how the anticipated $175 million annual cost would be funded.

14 Jan 2011

WHO, Roll Back Malaria partnership launch initiative to contain artemisinin-resistant malaria

The WHO and Roll Back Malaria partnership (RBM) on Wednesday launched an initiative to "stop a form of drug-resistant malaria from spreading from Southeast Asia to Africa, where millions of lives could be at risk," Reuters reports. "It would cost about $175 million a year to contain and prevent the global spread of the artemisinin-resistant parasite which first emerged along the Thai-Cambodian border in 2007, the United Nations agency said," according to the news agency (Nebehay, 1/12).

13 Jan 2011

Drug resistant malaria on the prowl

Experts have warned that drug-resistant malaria could spread from Southeast Asia to Africa within months, putting millions of children’s lives at risk. Nicholas White, professor of tropical medicine at Mahidol University in Bangkok warned that a malaria strain resistant to the drug artemisinin that first emerged along the Thai-Cambodian border in 2007.

12 Jan 2011

The Scientist examines how nonprofit, for-profit pharma groups are working together to make drugs more affordable for developing countries

"With philanthropists funneling billions of dollars into biomedical research and traditional drug discovery efforts producing fewer and fewer therapies, the line between for-profit and nonprofit life science companies is beginning to blur as both sides of the divide look for new options," The Scientist magazine writes in an article that examines the rise in collaborations between nonprofit pharmaceutical companies and for-profit groups.

4 Jan 2011

WHO report shows significant progress in global malaria fight, highlights need for continued funding

Since 2008, global malaria control efforts have "helped reduce infections across Africa and [eliminate] the disease in Morocco and Turkmenistan, but a slowdown in funding risks undoing those achievements," according to the WHO's annual malaria report, which was released on Tuesday, Reuters reports (Nebehay, 12/14).

16 Dec 2010

Global Fund to draw up action plan against drug theft, invites stakeholders to participate

The Global Fund to Fight AIDS, Tuberculosis and Malaria on Friday appealed to international donors to join them in an effort to fight medicine theft, SAPA/News24 reports.

15 Dec 2010

Emergency artesunate suppositories are cost-effective intervention for children with suspected severe malaria

Giving emergency artesunate suppositories to children with suspected severe malaria before referring them for treatment is a cost-effective intervention that can substantially improve the management of childhood malaria in remote African settings, according to a new study led by Boston University School of Public Health [BUSPH] researcher Yesim Tozan, PhD.

30 Nov 2010

One-third of malaria-endemic countries are complying with WHO malaria drug efficacy monitoring standards, report says

Thirty-four percent of malaria-endemic countries are complying with WHO guidelines to monitor artemisinin resistance within their borders, the agency said in a report on Thursday, CBS News reports (11/18). Reuters reports that artemisinin "is the best drug available against malaria, especially when used in artemisinin combination therapy (ACT), which combines it with other drugs that finish off the [malaria] parasite" (Nebehay, 11/18).

20 Nov 2010

National monitoring essential for preventing emergence of malaria drug resistance

WHO is calling on countries to be increasingly vigilant in monitoring antimalarial drug efficacy in order to allow for early detection of artemisinin resistance.1 This is one among several conclusions of the Global report on antimalarial drug efficacy and drug resistance: 2000-2010, released today. The report is based on 1100 studies conducted by national malaria control programs and research institutes over the ten-year period.

19 Nov 2010

New malaria drug can save millions of lives: Study

A landmark trial showed that the replacement of the standard malaria drug Quinine with the newer drug Artesunate for children with severe malaria could save 100,000 lives a year. The World Health Organisation (WHO) recommended that artesunate derived from a Chinese plant called sweet wormwood, replace the four-century-old remedy of quinine for treating severe malaria in adults in 2006. Similar recommendations were not made for children with further trial results pending.

8 Nov 2010

NBER project identifies and analyzes African successes

Conventional wisdom has long been negative on Africa. Historically, it has been seen as a failing continent, plagued by deep-rooted problems - poverty, corruption, war, and disease. But after four decades of relative stagnation, Africa has been growing rapidly. Since the 1990s, many African countries have seen economic and political improvements, more transparent elections, increased democracy and freedom of press. But these successes are not well understood.

21 Oct 2010