Arterial Stiffness News and Research

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Arteries stiffen as a consequence of age and atherosclerosis. The two leading causes of death in the developed world, myocardial infarction and stroke, are both a direct consequence of atherosclerosis. Increased arterial stiffness is associated with an increased risk of cardiovascular events.

Elderly people with hardening of arteries are more likely to have beta-amyloid plaques in brain

Even for elderly people with no signs of dementia, those with hardening of the arteries are more likely to also have the beta-amyloid plaques in the brain that are a hallmark of Alzheimer's disease, according to a study published in the October 16, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology.

17 Oct 2013

Vitamin D supplementation does not improve blood pressure in hypertension patients

Vitamin D supplementation does not appear to improve blood pressure or markers of vascular health in older patients with isolated systolic hypertension (a common type of high blood pressure), according to a study by Miles D. Witham, Ph.D., of the University of Dundee, Scotland, United Kingdom, and colleagues.

13 Aug 2013

New study examines arterial stiffening in young, healthy population

Indiana University researchers found that people in their 20s already began to demonstrate arterial stiffening -- when arteries become less compliant as blood pumps through the body -- but their highly active peers did not.

1 Jun 2013

Aortic arch pulse wave velocity predicts disease of the vessels that supply blood to the brain

Aortic arch pulse wave velocity, a measure of arterial stiffness, is a strong independent predictor of disease of the vessels that supply blood to the brain, according to a new study published in the June issue the journal Radiology.

24 May 2013

Metabolic risk factors in overweight children linked with mild artery wall stiffness

Metabolic disorders, such as excess abdominal fat, raised blood pressure, higher levels of insulin, glucose and triglycerides and lower levels of the beneficial HDL cholesterol can be found in children as young as 6 to 8 years of age, according to a study carried out at the University of Eastern Finland.

26 Apr 2013

Omeros' GPCR platform unlocks new drug targets against multiple sclerosis

Omeros Corporation today announced positive data in the most commonly used model for studying the clinical and pathological features of multiple sclerosis (MS), further advancing its development program of GPR17-targeting compounds for the treatment of MS. Compounds previously discovered by Omeros that inhibit GPR17, an orphan G protein-coupled receptor (GPCR) unlocked by Omeros, significantly improved function from experimental autoimmune encephalomyelitis (EAE) in mice.

11 Apr 2013

Nutrisystem reduces arterial stiffness associated with menopause and obesity

Arturo Figueroa, a researcher in the Florida State University College of Human Sciences, has confirmed with a team of researchers that Nutrisystem, with or without low intense resistance exercise, improves arterial function in obese, postmenopausal women.

9 Jan 2013

Arterial elasticity link to lung function

People with reduced arterial elasticity may have impaired lung function, and vice versa, say US researchers.

8 Jan 2013

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Blocking the receptor for proteins that constrict blood vessels reduces markers of heart-related problems in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Patients with obstructive sleep apnea have same early cardiovascular damage as diabetics

Patients with obstructive sleep apnea have the same early cardiovascular damage as diabetics, according to research presented at EUROECHO and other Imaging Modalities 2012.

5 Dec 2012

Young vascular systems adapt to obesity

Researchers have identified physiologic changes in the vascular systems of children that appear to be an adaptive response to obesity.

27 Nov 2012

Study illuminates how Aldo and galectin-3 protein contribute to vascular remodeling, CHF

Cardiovascular disease will kill nearly 2.5 million people in the United States this year, according to the Centers for Disease Control. Over time, inflammation, collagen deposition and scar tissue formation can cause blood vessels to stiffen, a process called vascular fibrosis. Though researchers have known that the hormone aldosterone (Aldo) plays a role in this process, the precise mechanisms have been poorly understood.

17 Nov 2012

Workout in the catheter lab gives clues to ‘warm-up angina’

Improved coupling of vascular and ventricular circulation during exercise appears to underlie the phenomenon known as warm-up angina, a UK study shows.

6 Nov 2012

Anti-TNF-α therapy reduces CVD risk in patients with rheumatoid arthritis

Patients with rheumatoid arthritis exhibit a sub-clinical vasculitis that may underlie their increased risk for cardiovascular disease, shows research.

5 Nov 2012

Apolipoprotein E plays a major role in maintaining arterial softness

Arterial stiffening has long been considered a major risk factor for cardiovascular disease. Keeping arteries soft and supple might reduce disease risk, but the mechanisms of how arteries stave off hardening has remained elusive.

2 Nov 2012

Soccer scores hat-trick for hypertensive men

Soccer training can significantly reduce blood pressure and improve aerobic fitness in hypertensive middle-aged men, researchers say.

17 Oct 2012

Lonafarnib proves effective for children with progeria

Results of the first-ever clinical drug trial for children with Progeria, a rare, fatal "rapid-aging" disease, demonstrate the efficacy of a farnesyltransferase inhibitor (FTI), a drug originally developed to treat cancer. The clinical trial results, completed only six years after scientists identified the cause of Progeria, included significant improvements in weight gain, bone structure and, most importantly, the cardiovascular system, according to The Progeria Research Foundation (PRF) and Boston Children's Hospital.

25 Sep 2012

Renal denervation regenerates blood vessels and could reduce cardiovascular events

Renal denervation improves blood pressure and arterial stiffness in patients with therapy resistant hypertension, according to research presented at ESC Congress 2012 by Mr Klaas Franzen from the University Hospital of Schleswig-Holstein.

28 Aug 2012

DTU develops new computer model for AAA rupture risk evaluation

A new computer model is expected to assist the medical doctors in saving patients with this potential life threatening condition. Assistant Professor Marie Sand Enevoldsen at the Technical University of Denmark (DTU) has developed a prototype computer model for AAA rupture risk evaluation.

6 Jul 2012

Symposium at EuroPRevent 2012 highlights benefits of oily fish consumption

Most people, whether healthy or having cardiovascular disease (CVD), would benefit from regular consumption of oily fish, concluded speakers at the EuroPRevent 2012 meeting. While eating whole fish undoubtedly offers the optimum approach for increasing omega-3 intakes in both primary and secondary prevention, delegates heard, supplements have a major role to play in increasing omega-3 intakes for people who do not like fish.

3 May 2012