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Asthma is a common inflammatory disease affecting the airways that leads to shortness of breath, coughing and wheezing. Symptoms range from mild to severe but are generally manageable with appropriate treatment.

When asthmatics come into contact with something that irritates their lungs, three main changes occur that prevent air from moving easily through the airways. The bands of muscle surrounding the airways tighten and narrow the airway (bronchospasm), the lining of the airways inflame, and the cells that line the airways produce more mucus. This bronchospasm, inflammation, and mucus production lead to wheezing, coughing and difficulty in breathing.

An asthma “attack” refers to when the onset of symptoms is severe. In rare cases, an asthma attack can be life threatening and hospitalization may be required to provide emergency treatment.
The exact cause of asthma is not yet clear, but examples of factors that are known to trigger the condition include allergens such as house dust mites or pollen, cigarette smoke, exercise, chest infections, and exposure to cold air.

Asthma cannot be cured but it can be controlled. One of the most important parts of asthma control is identifying asthma triggers so they can be avoided wherever possible. Medications that may be used include anti-inflammatories to reduce swelling and mucus production and bronchodilators to relax the muscles that tighten and narrow the airways.
Physicians urge households to add 'clean my medicine cabinet' to Spring cleaning chores list

Physicians urge households to add 'clean my medicine cabinet' to Spring cleaning chores list

After marijuana and alcohol, the most commonly abused drugs by those over the age of 14 are prescription and over-the-counter medications. [More]
Genetic decanalization can lead to complex genetic diseases in humans

Genetic decanalization can lead to complex genetic diseases in humans

The information encoded in the DNA of an organism is not sufficient to determine the expression pattern of genes. This fact has been known even before the discovery of epigenetics, which refers to external modifications to the DNA that turn genes "on" or "off". [More]
Study finds racial disparities among children with Crohn's disease

Study finds racial disparities among children with Crohn's disease

A study published recently in the IBD Journal found significant differences in hospital readmissions, medication usage, and both medical and surgical complications of children with Crohn's disease related to race. In the study, black children had a 1.5 times higher frequency of hospital readmissions because of Crohn's disease compared to white children. [More]
Village Capital, Texas Medical Center to join for Health IT Venture Forum

Village Capital, Texas Medical Center to join for Health IT Venture Forum

Join Village Capital and the Texas Medical Center on March 4, 2015, for our Health IT Venture Forum showcasing 8 enterprises bridging the "health-wealth" gap. [More]
MIT researchers devise new way to make complex emulsions

MIT researchers devise new way to make complex emulsions

MIT researchers have devised a new way to make complex liquid mixtures, known as emulsions, that could have many applications in drug delivery, sensing, cleaning up pollutants, and performing chemical reactions. [More]
Regeneron announces EU approval of EYLEA (aflibercept) Injection for retinal vascular disease treatment

Regeneron announces EU approval of EYLEA (aflibercept) Injection for retinal vascular disease treatment

Regeneron Pharmaceuticals, Inc. today announced that EYLEA (aflibercept) Injection has been approved by the European Commission for the treatment of visual impairment due to Macular Edema secondary to Retinal Vein Occlusion (RVO). [More]
Reslizumab drug appears to reduce risk of severe asthma attacks

Reslizumab drug appears to reduce risk of severe asthma attacks

An investigational drug appears to cut the risk of severe asthma attacks in half for patients who have difficulty controlling the disorder with standard medications, according to results from two multicenter clinical trials. [More]
Indiana University study reveals connection between mussels and muscles

Indiana University study reveals connection between mussels and muscles

An Indiana University study has revealed that there may be a greater connection between mussels and muscles than previously thought. [More]
Teen girls from rural areas have undiagnosed asthma, face higher risk of depression

Teen girls from rural areas have undiagnosed asthma, face higher risk of depression

Teen girls who live in rural areas are more likely than their male counterparts to have undiagnosed asthma, and they often are at a higher risk of depression, according to researchers at the Medical College of Georgia at Georgia Regents University. [More]
PCDS AC system optimizes delivery of anticoagulation drugs, reduces adverse events

PCDS AC system optimizes delivery of anticoagulation drugs, reduces adverse events

Point of Care Anticoagulation software (PCDS AC) optimizes delivery of anticoagulation drugs and reduces adverse events associated with anticoagulation therapy. The software was designed and developed in collaboration with leading clinical thrombosis experts, and is a decision support tool that takes the complexity out of AC management by providing a real-time AC dashboard. With intuitive, predictive clinical decision support, PCDS AC transforms evidence-based guidelines into intelligent tools that measure and improve AC therapy outcomes. [More]
Two Glenmark manufacturing facilities in India win Greentech Environment Gold Award - 2015

Two Glenmark manufacturing facilities in India win Greentech Environment Gold Award - 2015

Two manufacturing facilities of Glenmark located in Goa and Nashik bagged the prestigious 'Greentech Environment Gold Award - 2015' for Excellence in Environment Management at a ceremony in Kolkata recently. Greentech Environment Awards are presented ever year to companies/units in India demonstrating the highest level of commitment to Environmental Management across different sectors. [More]
Shire announces acquisition of Meritage Pharma

Shire announces acquisition of Meritage Pharma

Shire plc and Meritage Pharma, Inc. announced today that Shire has acquired Meritage, a privately-held company, for an upfront fee of $70 million and additional contingent payments based on the achievement of development and regulatory milestones. [More]
Boehringer Ingelheim presents Phase III data for tiotropium at 2015 AAAAI Annual Meeting

Boehringer Ingelheim presents Phase III data for tiotropium at 2015 AAAAI Annual Meeting

Boehringer Ingelheim today presented data on investigational tiotropium delivered via Respimat inhaler from five Phase III trials from the UniTinA-asthma program at the 2015 American Academy of Allergy, Asthma & Immunology Annual Meeting in Houston, Texas. [More]
Rigel, Bristol-Myers Squibb partner to develop, commercialize TGF beta receptor kinase inhibitors

Rigel, Bristol-Myers Squibb partner to develop, commercialize TGF beta receptor kinase inhibitors

Rigel Pharmaceuticals, Inc. and Bristol-Myers Squibb Company today announced that they have entered into a collaboration agreement for the discovery, development and commercialization of cancer immunotherapies based on Rigel's extensive portfolio of small molecule TGF beta receptor kinase inhibitors. [More]
Henry Ford researchers say that breastfeeding influences baby's immune system development

Henry Ford researchers say that breastfeeding influences baby's immune system development

Henry Ford Hospital researchers say that breastfeeding and other factors influence a baby's immune system development and susceptibility to allergies and asthma by what's in their gut. [More]
Epigenome-wide association study helps discover genes linked to allergies and asthma

Epigenome-wide association study helps discover genes linked to allergies and asthma

Researchers from Canada, the UK, Sweden and the US have discovered more than 30 genes that strongly affect an antibody involved in allergies and asthma. Some of the genes could provide targets for drugs to treat those conditions, according to the international team's study, published online in Nature on Feb. 18. [More]
Researchers demonstrate clinical efficacy of gallopamil in severe asthma patients

Researchers demonstrate clinical efficacy of gallopamil in severe asthma patients

A team of Inserm researchers from the Cardio-Thoracic Research Centre of Bordeaux (Inserm/University of Bordeaux and Bordeaux University Hospital) has demonstrated the clinical efficacy of gallopamil in 31 patients with severe asthma. This chronic disease is characterised by remodelling of the bronchi, which exacerbates the obstruction of the airways already seen in "classic" asthma. [More]
New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

New study turns to epigenetics to look for new therapeutic targets to treat allergic diseases

Scientists have discovered over 30 new genes that predispose people to allergies and asthma, some of which could be targets for new drugs. [More]
Researchers find potential new target to treat asthma patients

Researchers find potential new target to treat asthma patients

Researchers have found a potential new target for treating asthma, according to a study led by researchers at the University of Colorado School of Medicine at the Anschutz Medical Campus and published in the journal Nature Communications. [More]
Study findings could lead to new potential drug targets for allergic diseases

Study findings could lead to new potential drug targets for allergic diseases

Scientists have discovered over 30 new genes that predispose people to allergies and asthma, some of which could be targets for new drugs. [More]