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Asthma is a common inflammatory disease affecting the airways that leads to shortness of breath, coughing and wheezing. Symptoms range from mild to severe but are generally manageable with appropriate treatment.

When asthmatics come into contact with something that irritates their lungs, three main changes occur that prevent air from moving easily through the airways. The bands of muscle surrounding the airways tighten and narrow the airway (bronchospasm), the lining of the airways inflame, and the cells that line the airways produce more mucus. This bronchospasm, inflammation, and mucus production lead to wheezing, coughing and difficulty in breathing.

An asthma “attack” refers to when the onset of symptoms is severe. In rare cases, an asthma attack can be life threatening and hospitalization may be required to provide emergency treatment.
The exact cause of asthma is not yet clear, but examples of factors that are known to trigger the condition include allergens such as house dust mites or pollen, cigarette smoke, exercise, chest infections, and exposure to cold air.

Asthma cannot be cured but it can be controlled. One of the most important parts of asthma control is identifying asthma triggers so they can be avoided wherever possible. Medications that may be used include anti-inflammatories to reduce swelling and mucus production and bronchodilators to relax the muscles that tighten and narrow the airways.
FDA approves EYLEA Injection for treatment of Diabetic Macular Edema

FDA approves EYLEA Injection for treatment of Diabetic Macular Edema

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has approved EYLEA (aflibercept) Injection for the treatment of Diabetic Macular Edema (DME). [More]
Researchers working to develop new drugs for treating chronic inflammatory diseases

Researchers working to develop new drugs for treating chronic inflammatory diseases

Science and industry are collaborating to develop future pharmaceuticals for treating chronic inflammatory diseases. The medicines will combat immunological processes that have gone wrong. [More]
Iowa researchers develop vaccine to combat dust-mite allergies

Iowa researchers develop vaccine to combat dust-mite allergies

Researchers at the University of Iowa have developed a vaccine that can combat dust-mite allergies by naturally switching the body's immune response. [More]
New research reveals how expectations about odors can influence symptoms of asthma

New research reveals how expectations about odors can influence symptoms of asthma

New research from the Monell Center reveals that simply believing that an odor is potentially harmful can increase airway inflammation in asthmatics for at least 24 hours following exposure. The findings highlight the role that expectations can play in health-related outcomes. [More]
Exercise-induced wheezing risk increases with asthma severity

Exercise-induced wheezing risk increases with asthma severity

Exercise-induced wheezing is associated with the severity of asthma, according to the findings of a large, cross-sectional survey conducted in Japanese children. [More]
Surrogate marker identified for airway obstruction and asthma control

Surrogate marker identified for airway obstruction and asthma control

Researchers have identified a potential biomarker for airway obstruction in patients with asthma that not only reflects airflow limitation but also asthma control. [More]
Site of eosinophilic inflammation important in asthma control

Site of eosinophilic inflammation important in asthma control

The site of eosinophilic inflammation, whether local, systemic or both, has a significant effect on lung function, bronchial hyperresponsiveness and asthma control, study findings show. [More]
Viewpoints: Democrats' hypocrisy on suing Presidents; what's slowing health care costs?

Viewpoints: Democrats' hypocrisy on suing Presidents; what's slowing health care costs?

In the tiny House Rules Committee room in Congress on Wednesday, New York Democrat Louise Slaughter let roll her grievances against House Republicans' lawsuit against Barack Obama. It took a lot of coffee. [More]
Phase 3 VIVID-DME trial of EYLEA Injection for treatment of DME shows improvement in visual acuity

Phase 3 VIVID-DME trial of EYLEA Injection for treatment of DME shows improvement in visual acuity

Regeneron Pharmaceuticals, Inc. today announced that in the Phase 3 VIVID-DME trial of EYLEA® (aflibercept) Injection for the treatment of diabetic macular edema (DME), EYLEA 2 milligrams (mg) dosed monthly (2Q4) and EYLEA 2 mg dosed every two months (after 5 initial monthly injections, 2Q8) showed a sustained improvement from baseline in best corrected visual acuity (BCVA) at week 100 (2 years), compared to laser photocoagulation. [More]
Asthma inhalers may suppress children's growth

Asthma inhalers may suppress children's growth

Corticosteroid drugs that are given by inhalers to children with asthma may suppress their growth, evidence suggests. Two new systematic reviews published in The Cochrane Library focus on the effects of inhaled corticosteroid drugs (ICS) on growth rates. [More]
New online tool launched to help asthmatics breathe easier

New online tool launched to help asthmatics breathe easier

Incorrect asthma inhaler technique is one of the leading causes of poorly-controlled asthma. Despite receiving adequate treatment, poor adherence and using asthma inhalers incorrectly contributes to people not getting the most out of their medicines. [More]
Glenmark plans to set up new manufacturing facility at Monroe Corporate Center, USA

Glenmark plans to set up new manufacturing facility at Monroe Corporate Center, USA

Glenmark Pharmaceuticals Ltd, a research-driven, global, integrated pharmaceutical company, plans to set up a new manufacturing facility in the US. [More]
New book addresses safe and effective exercises for overweight children

New book addresses safe and effective exercises for overweight children

Safe and Effective Exercise for Overweight Youth by Melinda Sothern, PhD, Director of Behavioral & Community Health Sciences and Professor of Research at the LSU Health Sciences Center New Orleans School of Public Health, provides exercise recommendations and guidelines specifically designed for overweight youth. [More]
Scientists launch project on northern Front Range of Colorado to track harmful pollutant

Scientists launch project on northern Front Range of Colorado to track harmful pollutant

Scientists at the National Center for Atmospheric Research (NCAR) and partner organizations from across the country are launching a major field project on the northern Front Range of Colorado this month to track the origins of summertime ozone, an invisible but harmful pollutant. [More]
Localised inflammation found in eosinophilic otitis media

Localised inflammation found in eosinophilic otitis media

Antigen-specific immunoglobulin E is produced locally in the middle ear mucosa of patients with eosinophilic otitis media, clinical research indicates. [More]
Interaction between 2 proteins can be responsible for allergic asthma after eating infected fruit

Interaction between 2 proteins can be responsible for allergic asthma after eating infected fruit

Researchers at the UPM suggest that the interaction between two proteins can be the responsible for the allergic asthma episodes after eating an infected fruit. [More]
Acupuncture can affect severity of hot flashes for women in natural menopause

Acupuncture can affect severity of hot flashes for women in natural menopause

In the 2,500+ years that have passed since acupuncture was first used by the ancient Chinese, it has been used to treat a number of physical, mental and emotional conditions including nausea and vomiting, stroke rehabilitation, headaches, menstrual cramps, asthma, carpal tunnel, fibromyalgia and osteoarthritis, to name just a few. [More]
Researchers create combination drug that controls both tumor growth and metastasis

Researchers create combination drug that controls both tumor growth and metastasis

Researchers at UC Davis, University of Massachusetts and Harvard Medical School have created a combination drug that controls both tumor growth and metastasis. By combining a COX-2 inhibitor, similar to Celebrex, and an epoxide hydrolase (sEH) inhibitor, the drug controls angiogenesis (blood vessel formation), limiting a tumor's ability to grow and spread. [More]
New research opens up potential new therapeutic targets for hard-to-treat food allergy

New research opens up potential new therapeutic targets for hard-to-treat food allergy

New research in Nature Genetics identifies a novel genetic and molecular pathway in the esophagus that causes eosinophillic esophagitis (EoE), opening up potential new therapeutic strategies for an enigmatic and hard-to-treat food allergy. [More]

People who grow up farm with livestock better protected against inflammatory bowel diseases

New research conducted at Aarhus University has revealed that people who have grown up on a farm with livestock are only half as likely as their urban counterparts to develop the most common inflammatory bowel diseases: ulcerative colitis and Crohn's disease. [More]