Autoantibodies News and Research

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CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

New research at ACR Convergence 2023, the American College of Rheumatology's annual meeting, demonstrates that CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus while maintaining a robust response to vaccines.

7 Nov 2023

Experts develop equitable quality measures to improve lupus care by 2030

Leaders of a project to develop and implement equitable new quality measures for lupus care by the end of the decade will present their work at ACR Convergence 2023, the American College of Rheumatology's annual meeting.

7 Nov 2023

Positive antiphospholipid antibodies linked to increased cardiovascular risk in lupus patients

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, describes a link between positive antiphospholipid antibodies and an increased risk of future cardiovascular disease in patients with systemic lupus erythematosus (SLE).

7 Nov 2023

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, shows that ultrasound-detected salivary gland abnormalities in primary Sjögren's become more severe over time and that the slow-to-progress disease likely starts long before it is first detected.

7 Nov 2023

Cutting-edge 'precision medicine' shows great potential to improve diabetes care

Cutting-edge “precision medicine” has great potential to advance the diagnosis, treatment and ultimate prevention of different forms of diabetes, an international coalition of scientists reports in a sweeping assessment of the state of the field around the world.

6 Nov 2023

Linking perinatal events to juvenile idiopathic arthritis-uveitis

Researchers investigate perinatal events associated with the manifestation of juvenile idiopathic arthritis and the development of JIA-uveitis.

20 Oct 2023

Early eating habits shape celiac disease risk in young kids, study shows

This long-term study reveals that dietary patterns in the first two years of life can significantly influence the risk of developing celiac disease autoimmunity (CDA) and celiac disease in genetically predisposed children. High intake of vegetable fats and milk at 9 months reduced CDA risk, while at 24 months, certain foods like wheat and vegetable fats increased the risk, emphasizing the role of non-gluten dietary factors.

17 Oct 2023

Falling folate levels sound alarm for urgent UK food fortification

A study from the University of Cambridge used UK National Diet and Nutrition Survey data from 2008-2019 to examine folate levels, particularly in females of reproductive age. The study found a significant decline in both RBC and serum folate concentrations across all age groups, emphasizing the need for mandatory folic acid fortification in the UK.

16 Oct 2023

International report paves way for precision diabetes medicine breakthrough

Precision medicine for prevention, diagnosis, treatment, and prognosis for Diabetes.

9 Oct 2023

Universal screening: A game-changer in early detection and management of type 1 diabetes

Dr. Emily K. Sims discusses the crucial role of universal type 1 diabetes (T1D) screening in early detection, especially in individuals without a family history, at the EASD Annual Meeting. This proactive approach, aligned with disease-modifying therapies, aims to prevent severe diabetic ketoacidosis episodes, marking a stride towards better management of T1D.

3 Oct 2023

Long COVID's biological blueprint: new study offers promising insights

Researchers designed a cross-sectional study to investigate the biological underpinnings of “Long COVID”, the post-acute infection syndrome triggered by SARS-CoV-2.

27 Sep 2023

COVID-19 doubles risk of early type 1 diabetes signs in high-risk children

New research in JAMA finds a temporal association between SARS-CoV-2 infections and the onset of islet autoimmunity, a precursor to type 1 diabetes, in genetically predisposed infants. The study underscores COVID-19 as a potential risk factor for the development of this form of diabetes in young children.

13 Sep 2023

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

An article published in NPJ Aging, a Springer Nature journal, reveals that natural production of auto-antibodies increases with age and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19.

12 Sep 2023

Study reports an increase in incidence of islet autoimmunity after SARS-CoV-2 infection in young children

Type 1 diabetes is an autoimmune disease leading to an impaired glucose metabolism and requires life-long administration of insulin.

8 Sep 2023

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

COVID-19 can increase the risk of various autoimmune diseases; however, this risk appears to be mitigated by vaccination against COVID-19.

21 Aug 2023

Study shows that anti-PTM antibodies are often present in autoimmune mediated liver disease

A recent study published in Frontiers in Medicine described anti-post-translational modification (PTM) antibodies in patients with autoimmune-mediated and cholestatic liver diseases (AILD).

31 Jul 2023

DFG funds new clinical research unit to study autoimmune-mediated neurological diseases

How do neurological disorders arise that are caused, triggered, or influenced by antibodies? What better possibilities are there for diagnosis – and above all for treatment? These are the questions addressed by the new Clinical Research Unit "BecauseY" headed by Charité – Universitätsmedizin Berlin. Innovative treatment options will especially benefit patients who at first glance are not suspected of having an antibody-mediated neurological disease.

14 Jul 2023

Autoantibodies News and Research

CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus

Experts develop equitable quality measures to improve lupus care by 2030

Positive antiphospholipid antibodies linked to increased cardiovascular risk in lupus patients

Salivary gland abnormalities in primary Sjögren's become more severe over time, study shows

Cutting-edge 'precision medicine' shows great potential to improve diabetes care

Linking perinatal events to juvenile idiopathic arthritis-uveitis

Early eating habits shape celiac disease risk in young kids, study shows

Falling folate levels sound alarm for urgent UK food fortification

International report paves way for precision diabetes medicine breakthrough

Universal screening: A game-changer in early detection and management of type 1 diabetes

Long COVID's biological blueprint: new study offers promising insights

COVID-19 doubles risk of early type 1 diabetes signs in high-risk children

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

Study reports an increase in incidence of islet autoimmunity after SARS-CoV-2 infection in young children

COVID-19 associated with increased risk of developing various autoimmune diseases and risk could be attenuated by vaccination

Study shows that anti-PTM antibodies are often present in autoimmune mediated liver disease

DFG funds new clinical research unit to study autoimmune-mediated neurological diseases

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

How B-cells and androgens contribute to the development of PCOS

Beyond the lungs: SARS-CoV-2's multi-organ impact revealed

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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