Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Zika virus (ZIKV) infection is a potentially teratogenic illness, causing up to one in seven infants born to infected mothers to suffer neurodevelopmental deficits. A new study published in the journal Cell shows that some mothers escape injury to their babies because they develop a highly potent neutralizing antibody.

22 Nov 2022

PALS program effective in ensuring diverse representation in lupus clinical trials

The Lupus Research Alliance and its affiliate Lupus Therapeutics presented data at ACR Convergence 2022 with results showing the effectiveness of a pilot peer education program called the Patient Advocates for Lupus Studies (PALS), in increasing knowledge, perception, and willingness among people with Systemic Lupus Erythematosus (SLE) to participate in clinical trials.

14 Nov 2022

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

Type I interferon (IFN) is a powerful immune activator that is present at high levels in the majority of patients with lupus, an autoimmune disease. In Arthritis & Rheumatology, researchers report positive results from the first placebo-controlled long-term trial of anifrolumab-;a human monoclonal antibody that targets the type I IFN receptor-;in patients with lupus.

14 Nov 2022

Research reveals why stem cell transplants are so successful in MS patients

Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study led by the University of Zurich has now examined in detail the way in which the treatment curbs the autoimmune disease and how the immune system regenerates afterwards.

10 Nov 2022

TYK2 inhibitor identifies as a promising drug candidate for preventing type 1 diabetes

According to a study, type 1 diabetes could be prevented by inhibiting a gene associated with the onset of the disease.

10 Nov 2022

Skipping methotrexate for one week after flu vaccine provides the same seroprotection as a two-week hold in RA patients

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, showed that discontinuing methotrexate for one week after seasonal influenza vaccination provided the same seroprotection as a two-week discontinuation period in patients with rheumatoid arthritis.

8 Nov 2022

Spine disease in CRMO patients found to be more common than previously believed

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, shows that spine disease, once considered a rarity in chronic recurrent multifocal osteomyelitis, affects as many as 10-35% of patients and is asymptomatic in one-third.

8 Nov 2022

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Researchers identified a genetic association signal, via genome-wide association studies, between severe COVID-19 with systemic lupus erythematosus, an autoimmune disease.

7 Nov 2022

Rutgers physicians take newer approach in successfully treating a mysterious disease

The prognosis for the sick child, who hadn't responded to standard treatment, was dire. But a team of Rutgers physicians believed there might be hope despite the conventional wisdom against pursuing any further treatment.

27 Oct 2022

Unique gut bacteria could be responsible for triggering rheumatoid arthritis in at-risk people

Researchers at the University of Colorado School of Medicine have discovered that a unique bacteria found in the gut could be responsible for triggering rheumatoid arthritis (RA) in people already at risk for the autoimmune disease.

26 Oct 2022

RIT professor receives grant to investigate new therapeutic approaches for scleroderma

More collagen in the human body is not always good, and Karin Wuertz-Kozak is investigating how disease progresses because of the increase in this important protein.

25 Oct 2022

Scientists use systems biology approach to identify molecular players in rheumatoid arthritis

Using a novel systems biology approach, scientists at University of California San Diego School of Medicine have further parsed the cellular players and roles involved in rheumatoid arthritis (RA), a complex disease that affects more than one million Americans in ways that have defied development of uniform treatments.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders.

23 Oct 2022

Did the risk of severe COVID-19 in the immunodeficient population of the UK change following vaccination deployment?

Researchers evaluated the changing risk of severe COVID-19 outcomes in individuals with primary and secondary immunodeficiencies in the context of COVID-19 vaccinations.

17 Oct 2022

Researchers examine how fermented vegetables affect inflammation markers in women

Western females can consume 0.5 g of fermented vegetables each day for six weeks without experiencing any major side effects

16 Oct 2022

Study reveals why viral infections are less frequent but more severe in individuals with Down syndrome

Individuals with Down syndrome have less-frequent viral infections, but when present, these infections lead to more severe disease.

14 Oct 2022

Study may have solved a mystery surrounding Crohn’s disease

A new study may have solved a mystery surrounding Crohn's disease, a type of inflammatory bowel disease in which immune defenses meant to attack invading microbes instead mistakenly target the body's own digestive tract.

5 Oct 2022

Study reveals a testable hypothesis to explain the initiation of autoimmunity in T1D patients

Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively yet the mystery of what causes autoimmunity is unknown.

23 Sep 2022

Study shows 72% increase in new diagnoses of type 1 diabetes in young COVID-19 patients

Children who were infected with COVID-19 show a substantially higher risk of developing type 1 diabetes (T1D), according to a new study that analyzed electronic health records of more than 1 million patients ages 18 and younger.