Autoimmune Disease News and Research

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Autoimmune Disease is a condition in which the body recognizes its own tissues as foreign and directs an immune response against them.

Research finds link between increased hygiene and higher rates of certain diseases in women

Little girls growing up in western society are expected to be neat and tidy - "all ribbon and curls" - and one researcher who studies science and gender differences thinks that emphasis may contribute to higher rates of certain diseases in adult women.

27 Jan 2011

Study: Low SES is linked to high risk of depression in patients with RA

Physical and Mental Health Disparities Found in Those with Low Socioeconomic Position. A recent study confirmed that low socioeconomic status is associated with higher risk of depressive symptoms in patients with rheumatoid arthritis.

26 Jan 2011

TU Delft receives EU grant to diagnose and monitor Crohn's disease using MRI scans

Colonoscopy is the standard intestinal examination for diagnosing and monitoring Crohn's disease. It is a stressful procedure in which a flexible tube fitted with a camera is passed into the large intestine. MRI scans are therefore often used as an alternative to monitor the course of the disease and how it is responding to treatment.

25 Jan 2011

EU awards 3 million euros for improving assessment of MRI scans for Crohn’s disease

24 Jan 2011

SuppreMol completes successful pre-IND meeting with U.S. FDA

SuppreMol GmbH, a privately held biopharmaceutical company developing innovative therapeutics for the treatment of autoimmune diseases, today announced that it has successfully completed a pre-Investigational New Drug Application (pre-IND) meeting with the U.S. Food and Drug Administration (FDA) for its lead compound SM101, which is being developed for the treatment of Primary Immune Thrombocytopenia (ITP) and Systemic Lupus Erythematosus (SLE).

24 Jan 2011

American Academy of Dermatology's position statement on vitamin D reflects IOM's findings

The American Academy of Dermatology (Academy) has updated its position statement on vitamin D based on the results of a review of the increasing body of scientific literature on this vitamin and its importance for optimal health recently conducted by the National Academy of Sciences Institute of Medicine (IOM).

20 Jan 2011

First-ever global definition of lupus flare

The Lupus Foundation of America (LFA) spearheaded a four-year worldwide initiative with more than 120 lupus experts from 11 countries, the pharmaceutical and biotechnology industries, and federal agencies, which resulted in the first-ever global definition of a lupus flare. The development of Lupus Foundation of America Flare Definition (LFA-Flare) helps to overcome long-standing barriers to the development of new, safe, and more tolerable treatments for lupus.

11 Jan 2011

Emergent BioSolutions estimates total revenue of $285 to $288 million for 2010

Emergent BioSolutions Inc. announced today preliminary, unaudited financial results for 2010 and guidance for 2011.

10 Jan 2011

Biomarker study yields diagnostic blood test candidate for detection of Alzheimer's disease

OPKO Health, Inc. today announced the publication of a biomarker study yielding its diagnostic blood test candidate for the detection of Alzheimer's disease.

7 Jan 2011

Seattle Genetics enters ADC collaboration agreement with Pfizer

Seattle Genetics, announced today that it has entered into a collaboration agreement with Pfizer under which Pfizer will pay an upfront fee of $8 million for rights to utilize Seattle Genetics' antibody-drug conjugate technology with antibodies to a single oncology target.

7 Jan 2011

Athersys completes patient enrollment in MultiStem Phase I study for leukemia

Athersys, Inc. today announced that it has completed patient enrollment of the single dose arm of a clinical study involving administration of MultiStem to patients being treated for leukemia or other blood born cancers.

7 Jan 2011

Amgen, Xencor collaborate to develop XmAb5871 for autoimmune disease

Amgen and Xencor, announced today that they will collaborate to develop XmAb®5871, an Fc- engineered monoclonal antibody dually targeting CD19 and CD32b. XmAb5871 is currently in late-stage preclinical development for the treatment of autoimmune diseases.

7 Jan 2011

MacroGenics commences MGAH22 Phase I trail for patients with HER2-positive cancer

MacroGenics, a privately held biotechnology company that develops immunotherapeutics to treat autoimmune disorders, cancer and infectious diseases, today announced that it had administered drug to the first cohort of patients in a Phase I clinical trial of MGAH22.

6 Jan 2011

Lexicon Pharmaceuticals announces clinical trial, mechanistic study results of LX4211

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering breakthrough treatments for human disease, announced data from a recently completed clinical trial and mechanistic study of a solid oral dose formulation for LX4211, a dual inhibitor of sodium-glucose co-transporters 1 and 2 (SGLT1 and SGLT2).

6 Jan 2011

Symphogen closes €100 million stock to a group of investors

Symphogen, a private biopharmaceutical company developing superior antibody therapeutics to treat cancer, infectious and autoimmune diseases, announced today that it closed a €100 million placement of Preferred Stock to a group of investors.

6 Jan 2011

Mayo Clinic researchers estimate lifetime risk of developing rheumatoid arthritis in men and women

Mayo Clinic researchers have determined the lifetime risk of developing rheumatoid arthritis and six other autoimmune rheumatic diseases for both men and women. The findings appear online in Arthritis and Rheumatism.

6 Jan 2011

Past smoking history does not affect RA patient's response to treatments

Patients with early rheumatoid arthritis (RA) who are current smokers were less likely to achieve good response to methotrexate (MTX) and tumor necrosis factor (TNF) inhibitors than those who never smoked. The study by researchers from Sweden also found that RA patients who smoked in the past did not experience a lower response to these therapies. Results of the 10-year study appear in the January 2011 issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR).

4 Jan 2011

New research finds pattern for detecting 'false-positive' ANA results

The presence of antinuclear antibodies (ANA) indicates the possibility of autoimmunity and the indirect immunofluorescence (IIF) assay on HEp-2 cells is the standard blood test (ANA-HEp-2) used to detect ANA. However, studies have shown that a "false-positive" ANA test occurs in up to 13% of healthy individuals. In such cases the test detects the presence of autoantibodies that apparently are not associated with autoimmunity.

4 Jan 2011

Embryome Sciences announces $4M equity financing, changes name to ReCyte Therapeutics

BioTime, Inc. today announced a $4 million equity financing by its subsidiary, Embryome Sciences, Inc. Concurrent with the financing, Embryome Sciences will be renamed ReCyte Therapeutics, Inc. and will develop therapeutic products for cardiovascular and blood diseases. The new equity financing is being led by a $2.5 million investment by private investors and a $1.5 million investment from BioTime that valued ReCyte Therapeutics at a post money valuation of $60 million on a fully diluted basis.

4 Jan 2011

Vitamin D deficiency could be linked to development of certain autoimmune lung diseases

A new study shows that vitamin D deficiency could be linked to the development and severity of certain autoimmune lung diseases.

4 Jan 2011

Autoimmune Disease News and Research

Further Reading

Research finds link between increased hygiene and higher rates of certain diseases in women

Study: Low SES is linked to high risk of depression in patients with RA

TU Delft receives EU grant to diagnose and monitor Crohn's disease using MRI scans

EU awards 3 million euros for improving assessment of MRI scans for Crohn’s disease

SuppreMol completes successful pre-IND meeting with U.S. FDA

American Academy of Dermatology's position statement on vitamin D reflects IOM's findings

First-ever global definition of lupus flare

Emergent BioSolutions estimates total revenue of $285 to $288 million for 2010

Biomarker study yields diagnostic blood test candidate for detection of Alzheimer's disease

Seattle Genetics enters ADC collaboration agreement with Pfizer

Athersys completes patient enrollment in MultiStem Phase I study for leukemia

Amgen, Xencor collaborate to develop XmAb5871 for autoimmune disease

MacroGenics commences MGAH22 Phase I trail for patients with HER2-positive cancer

Lexicon Pharmaceuticals announces clinical trial, mechanistic study results of LX4211

Symphogen closes €100 million stock to a group of investors

Mayo Clinic researchers estimate lifetime risk of developing rheumatoid arthritis in men and women

Past smoking history does not affect RA patient's response to treatments

New research finds pattern for detecting 'false-positive' ANA results

Embryome Sciences announces $4M equity financing, changes name to ReCyte Therapeutics

Vitamin D deficiency could be linked to development of certain autoimmune lung diseases

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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