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Alzheimer’s disease specific brain deposits photographed for the first time in vivid detail

Scientists from the Britain's Medical Research Council Laboratory of Molecular Biology have for the first time, clearly pictured what the deposits typically seen in a person with Alzheimer’s disease look like. This is a breakthrough in neurodegenerative diseases. The latest study showing the structure of tau protein was published in the journal Nature.

5 Jul 2017

Research provides insight into role of APP gene variant in Alzheimer’s disease

New research from the University of Eastern Finland shows that the APP gene variant protecting against Alzheimer's disease significantly decreases plasma beta-amyloid levels in a population cohort.

20 Jun 2017

Study provides new insight into cells that rejuvenate the brain

Alzheimer's disease is a neurodegenerative disease manifested by various neuronal pathological processes and a significant decline in brain function.

9 Jun 2017

UT Southwestern research shows potential of new DNA vaccine in preventing Alzheimer’s disease

A new DNA vaccine when delivered to the skin prompts an immune response that produces antibodies to protect against toxic proteins associated with Alzheimer's disease – without triggering severe brain swelling that earlier antibody treatments caused in some patients.

23 May 2017

Newly identified biomarkers could help predict cognitive deficits in Parkinson's disease patients

New biomarkers identified by a research team in the Perelman School of Medicine at the University of Pennsylvania could help predict which Parkinson's disease patients will suffer significant cognitive deficits within the first three years of their diagnosis.

18 May 2017

Study reveals critical role of omega-3 fatty acids in preserving integrity of the blood-brain barrier

Already extolled for their health benefits as a food compound, omega-3 fatty acids now appear to also play a critical role in preserving the integrity of the blood-brain barrier, which protects the central nervous system from blood-borne bacteria, toxins and other pathogens, according to new research from Harvard Medical School.

5 May 2017

Gene mutation may accelerate loss of memory and thinking skills in people with Alzheimer's risk

A gene mutation may accelerate the loss of memory and thinking skills in people who are at risk for Alzheimer's disease, according to a study published in the May 3, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology. The gene mutation is called the BDNF Val66Met allele, or just the Met allele.

4 May 2017

Greebles may prove to be valuable tools in detecting early signs of Alzheimer's disease

Unique graphic characters called Greebles may prove to be valuable tools in detecting signs of Alzheimer's disease decades before symptoms become apparent.

11 Apr 2017

Changes in the vascular system could play role in initiating Alzheimer’s disease

As the average age of Americans increases, so too does the problem of Alzheimer's, one of the world's most common neurological diseases. In recent years, scientists have explored many new approaches to clear the plaques and tangles in the brain that characterize the condition, but the new drugs have largely turned out to be disappointing.

22 Mar 2017

Researchers produce images that predate formation of beta-amyloid plaques in Alzheimer’s disease

Researchers at Lund University in Sweden have used the MAX IV synchrotron in Lund - the strongest of its kind in the world - to produce images that predate the formation of toxic clumps of beta-amyloid, the protein believed to be at the root of Alzheimer's disease.

13 Mar 2017

Disappointing Merck drug news provides new blueprint for moving towards cure for Alzheimer's

The recent announcement that Merck is halting a Phase II/III study for a promising Alzheimer's treatment (verubecestat) was another setback in the continued and intensive effort to deliver an innovative therapy by 2020.

17 Feb 2017

MDI Biological Laboratory scientist sheds light on molecular mechanisms underlying aging

Scientists have known for decades that drastically restricting certain nutrients without causing malnutrition prolongs health and lifespan in a wide range of species, but the molecular mechanisms underlying this effect have remained a mystery.

17 Feb 2017

Study opens door to new opportunities for preventing and treating Alzheimer's disease

New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer's disease.

11 Feb 2017

Gut bacteria can accelerate development of Alzheimer’s disease, research shows

New research from Lund University in Sweden has shown that intestinal bacteria can accelerate the development of Alzheimer's disease. According to the researchers behind the study, the results open up the door to new opportunities for preventing and treating the disease.

10 Feb 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

Mediterranean plants may become source for 'elixir of life'

The Mediterranean is a haven for lovers of crystal-clear seas and sun-kissed landscapes. Now, thanks to the work of scientists from the University of Malta and the Centre National de la Recherche Scientifique, it has the added appeal of being an actual fountain of youth.

9 Jan 2017

Penn study finds evidence of AD neuropathology in post-mortem brains of LBD patients

Patients who had a diagnosis of Parkinson's disease (PD) with dementia (PDD) or dementia with Lewy bodies (DLB) and had higher levels of Alzheimer's disease (AD) pathology in their donated post-mortem brains also had more severe symptoms of these Lewy body diseases (LBD) during their lives, compared to those whose brains had less AD pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2017

Penn researchers pinpoint some effective HIV drugs in causing neuronal damage

Antiretroviral drugs have been life-changing therapies for HIV patients, but they can have significant side effects.

16 Dec 2016

Common anti-cholesterol drugs show promise for reducing Alzheimer's disease risk

Common anti-cholesterol drugs show promise for reducing the risk of Alzheimer's disease, a University of Southern California-led study of Medicare data reveals.

14 Dec 2016

Brain atrophy patterns linked to loss of specific cognitive abilities in patients with Alzheimer's disease

Mathematical modeling of the brain scans of patients with Alzheimer's disease and others at risk for the devastating neurodegenerative disorder has identified specific patterns of brain atrophy that appear to be related to the loss of particular cognitive abilities.

8 Oct 2016