Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

UC researchers open Phase 2 clinical trial to test new combination treatment for glioblastomas

A multidisciplinary team of University of Cincinnati Cancer Center researchers have opened a Phase 2 clinical trial to test a new combination treatment for glioblastomas (GBM), the most deadly form of brain tumors.

26 Mar 2024

Researchers shed light on proteins controlling the development of ovaries in mice

Researchers at the Francis Crick Institute have shed light on the proteins controlling the development of ovaries in mice before and after birth.

22 Mar 2024

Researchers design new bioinformatics tool to identify chromosomal alterations in cancer cells

A team of the University of Barcelona and the Biomedical Research Institute of Barcelona (IRB Barcelona) has designed a new bioinformatics tool to identify the chromosomal alterations that are characteristic of cancer cells.

21 Mar 2024

Severity of current SARS-CoV-2 variants is not linked to the number of mutations

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two most prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to previous variants.

19 Mar 2024

Gut bacteria and tryptophan diet can play a protective role against pathogenic E. coli

Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure, according to a study published March 13 in Nature.

14 Mar 2024

"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

By dissecting the genetic diversity of the most deadly human malaria parasite – Plasmodium falciparum – researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) have identified a mechanism of 'copy-paste' genetics that increases the genetic diversity of the parasite at accelerated time scales.

7 Mar 2024

New test rapidly detects dangerous germ in baby formula

Cronobacter sakazakii is a harmful germ that can be found in powdered baby formula. It can cause very serious health problems in infants, such as meningitis and septicemia.

5 Mar 2024

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

Scientists have developed a new screening tool to uncover how genetic changes affect gene activity and can lead to diseases such as cancer, autoimmunity, neurodegeneration and cardiovascular disease. This new tool enables the investigation of thousands of DNA mutations identified by genetic studies in one experiment, guiding the development of advanced diagnostics and treatments.

4 Mar 2024

New approach detects T cells in "cold" tumors, paves way for broader immunotherapy

Most cancers are thought to evade the immune system. These cancers don't carry very many mutations, and they aren't infiltrated by cancer-fighting immune cells. Scientists call these cancers immunologically "cold."

29 Feb 2024

New tool can streamline the analysis of complex epigenome and epitranscriptome data

Scientists have extensively researched the structure and sequence of genetic material and its interactions with proteins in the hope of understanding how our genetics and environment interact in diseases.

28 Feb 2024

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

28 Feb 2024

Harnessing multi-omics and AI for atherosclerotic cardiovascular disease management

Despite considerable life-saving progress, cardiovascular diseases (CVDs) remain the leading cause of death globally, claiming an estimated 17.9 million lives each year.

26 Feb 2024

Study reveals unexpected link between cell membrane damage and cellular senescence

Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap bubble. Cells are easily damaged by physiological activities, including muscle contraction and tissue injury.

22 Feb 2024

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

The University of Texas MD Anderson Cancer Center today was awarded 16 grants totaling over $25.5 million from the Cancer Prevention and Research Institute of Texas (CPRIT) in support of cancer screening, early detection and prevention programs, faculty recruitment, and groundbreaking cancer research across all areas of the institution.

21 Feb 2024

Researchers discover protein key to toxoplasmosis pathogen multiplication

Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.

16 Feb 2024

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects."

15 Feb 2024

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

Researchers from the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium of the National Institutes of Health, The University of Texas MD Anderson Cancer Center, Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and others, have unveiled a detailed understanding of immune responses in cancer, marking a significant development in the field.

14 Feb 2024

Bioinformatics News and Research

Further Reading

UC researchers open Phase 2 clinical trial to test new combination treatment for glioblastomas

Researchers shed light on proteins controlling the development of ovaries in mice

Researchers design new bioinformatics tool to identify chromosomal alterations in cancer cells

Severity of current SARS-CoV-2 variants is not linked to the number of mutations

Gut bacteria and tryptophan diet can play a protective role against pathogenic E. coli

"Copy-paste" genetic mechanism increases the genetic diversity of malaria parasite

New test rapidly detects dangerous germ in baby formula

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

New approach detects T cells in "cold" tumors, paves way for broader immunotherapy

New tool can streamline the analysis of complex epigenome and epitranscriptome data

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

Harnessing multi-omics and AI for atherosclerotic cardiovascular disease management

Study reveals unexpected link between cell membrane damage and cellular senescence

CPRIT awards MD Anderson 16 grants to support cancer research and prevention

Researchers discover protein key to toxoplasmosis pathogen multiplication

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

Phosphoproteomic profiling reveals the complex interplay of immune cells in tumors

New AI tool revolutionizes protein function prediction

Novel assay enhances pediatric cancer treatment by identifying clinically relevant gene fusions

Gene editing gets a boost with new CRISPR-COPIES

Lab Diagnostics and Automation - Second Edition eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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